Natural Products in Chemical Biology PDF Download
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Author: Natanya Civjan
Publisher: John Wiley & Sons
ISBN: 1118101170
Category : Science
Languages : en
Pages : 437
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Book Description
Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.
Author: Natanya Civjan
Publisher: John Wiley & Sons
ISBN: 1118101170
Category : Science
Languages : en
Pages : 437
Get Book Here
Book Description
Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.
Author: Natanya Civjan
Publisher: John Wiley & Sons
ISBN: 1118434501
Category : Science
Languages : en
Pages : 657
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Book Description
An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
Author: Tadhg P. Begley
Publisher: Wiley-Blackwell
ISBN:
Category : Science
Languages : en
Pages : 756
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Book Description
The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.
Author: Ian W. Hamley
Publisher: John Wiley & Sons
ISBN: 1119698189
Category : Science
Languages : en
Pages : 238
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Book Description
Provides an interdisciplinary introduction to peptide science, covering their properties and synthesis, as well as many contemporary applications Peptides are biomolecules comprised of amino acids which play an important role in modulating many physiological processes in our body. This book presents an interdisciplinary approach and general introduction to peptide science, covering contemporary topics including their applicability in therapeutics, peptide hormones, amyloid structures, self-assembled structures, hydrogels, and peptide conjugates including lipopeptides and polymer-peptide conjugates. In addition, it discusses basic properties and synthesis clearly and concisely. Taking a logical approach to the subject, Introduction to Peptide Science gives readers the fundamental knowledge that is required to understand the cutting-edge material which comes later in the book. It offers readers in-depth chapter coverage of the basic properties of peptides; synthesis; amyloid and peptide aggregate structures; antimicrobial peptides and cell-penetrating peptides; and peptide therapeutics and peptide hormones. Introduces readers to peptide science, including synthesis and properties Provides unique content covering properties, synthesis, self-assembly, aggregation, and applications Summarizes contemporary topics in an accessible fashion including applications in therapeutics, peptide hormones, amyloid structures, self-assembled structures, hydrogels, and peptide conjugates including lipopeptides Presented at an introductory level for the benefit of students and researchers who are new to the subject Introduction to Peptide Science is an ideal text for undergraduate students of chemistry, biochemistry, and other related biological subjects, and will be a valuable resource for postgraduate students and researchers involved in peptide science and its applications.
Author: Gunter Meister
Publisher: Wiley-VCH
ISBN: 9783527322787
Category : Science
Languages : en
Pages : 0
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Book Description
Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998. Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope. The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.
Author: Augustin Ostace
Publisher: Alpha & Omega Sapiens - Uppublishing Being / Augustin Ostace
ISBN:
Category : Medical
Languages : en
Pages : 68
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Book Description
How could be changed out of classical concept of ANATOMY (ana-tomos = to cut off in small pieces) which is one of the strongest imprinted scientific concept within the minds of all biologic scientists still by centuries, with the philosophical concept as ANATOMOLOGY? i.e. the Science of Anatomy, the Philosophical Science of the Anatomy, which in turn, could be synthesized by anatomists and philosophers alike!... Our endeavor is to find out a road between the two basic forms of human knowledge, an aurea mediocritas of dreaming pathway of any metaphysical living system… Anatomologist
Author: Augustin Ostace
Publisher: Alpha & Omega Sapiens - Uppublishing Being / Augustin Ostace
ISBN:
Category : Philosophy
Languages : en
Pages : 71
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Book Description
…Sapiens – the Species to whom every human being belongs to, being considered a wise, a bipedal and a sapience intelligence Species… …Sapientology – the logos, the reason, the philosophy of the Sapiens, i.e., a philosophy of the sapience, a phylo-sophos of the wise… …Sapientologist – the one who’s trying to overcome the common view of the Species Sapiens, through a sapiential philosophy, psychology and theology, by rethinking primarily the prejudices which covers the obscure origins of the Sapiens, its becoming, or its possible development through a speciation (anagenesis) within the same Species, as Up-sapiens or Down-sapiens, or to another Species Sapiens (cladogenesis) as Post-sapiens or, the worst of all of them, the Anti-sapiens… …In this way, our topic within the book of the Sapientology & Sapientologist, will be a fierce debating between the individuality of the Species Sapiens seen as Human Being, having as front-man or front-being the Master of Being, and a beginner of this kind of sapientological philosophy, seen as a Schoolboy of Being… Sapientologist
Author: Augustin Ostace
Publisher: Alpha & Omega Sapiens - Uppublishing Being / Augustin Ostace
ISBN:
Category : Philosophy
Languages : en
Pages : 110
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Book Description
…European Union has been plagued by many crisis since its beginning (during the fifties and sixties as the periods following the ruins of the World War Two in Europe, then, during the seventies and eighties the raising of the Euro–Communism in founding countries as Germany and Italy, through terrorist organizations as “RAF” in Germany and “Brigate Rosse” in Italy, then, in the nineties with the falling of Communism in Eastern Europe with millions migrations from Eastern Europe towards Western Europe, adding another millions of refugees out of Africa and Asia, particularly out of Islam poor world within Europe Union… …Our book LEX SAPIENS is trying to reiterate the battlefields of the author with the remnants of communist regime in Eastern Europe, which instead of being condemned by the European Institutions (Council, Parliament, Commission), is further protected through many irrationalities done by the Europe Union as whole (regretfully, to many failures and mistakes within Europe Union, throughout of its 62 years of existence)… LEX SAPIENTOLOGIST
Author: Augustin Ostace
Publisher: Alpha & Omega Sapiens - Uppublishing Being / Augustin Ostace
ISBN:
Category : Philosophy
Languages : en
Pages : 82
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Book Description
…We are under pressure in re-thinking and um-thinking of the whole of the European Union history, after big waves of union’s earthquakes, by mentioning here the big financial crisis between 2008-2010, or Brexit of Great Britain in 2020, an embittered fought inside of the European Union between the years of 2016 and the present 2021… …It is not mentioned here the waves of migrants in the last ten years towards European Union, through which a world of social pathology is accompanied and enhanced by a dramatic pandemic’s world of biologic pathology, this worst issues of viral disease, out-breaking in the year 2019, ravaging uninterrupted the world ever since, till the present days of May 2021… …We will remake another configuration of the initial CONSTITUTION OF EUROPE, written and published with about 15 years ago, resembling a parallel dialectical becoming between a finisher and a re-finisher in constitution or between an influencer and re-influencer in social sciences… Terminology of different constitutions will be different in their substance and their semantics, reflecting the difference in temporality and creativity of the author, but the basic principles of ethics and morality are into the both constitutions, the sameness … If European Union needs a constitution, then, European Union must know the history of Europe, must know the inhabitants, the native, the people and citizens of Europe, the science and technology of Europe, the art and religions of Europe, the geography and demography of Europe, since the oldest times of Upper Paleolithic, of Neolithic, of Antiquity, of Middle Age, of Renaissance, of Enlightenment, of Modern Times and of present Third Millennium, all in detail, in reality, in morality and rationality… More than that, our Constitution of European Union is desired to be and to become, a pilot project in searching and researching in anthropo-sapientology, a vector of axiological and epistemological substance in knowledge and discoveries… Constitutionalist of European Union
Author: Augustin Ostace
Publisher: Alpha & Omega Sapiens - Uppublishing Being / Augustin Ostace
ISBN:
Category : Philosophy
Languages : en
Pages : 76
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Book Description
No one is an island entire of itself, whoever she or he is… Everyone out of Species Sapiens has been involved into Mankind, in the last of ca. about 50.000 years of the supposed age of our Species Sapiens, belonging to Genus Homo Anthropos, then to Hominid Family, Order Primate, Class Mammals, Phylum Vertebrata and Kingdom Animals… Ultimately, what is known, what is uncertain and what is unknown in our relationship Subconscious – Consciousness, could be a strong investigation through a synthesis between philosophy, theology and psychology, by trying to explain, at least in part, in which way the instinct of the ancestors of Species Sapiens (direct line through Primate – Hominids – Homo), had been changed in reason, while the ancestors biology of the surviving was changed into human technology of conquering… Reason and Technology (condensed within the concept of culture) both towards the creative conscious of human, through the mystery of neo-cortex, by preserving in the same time, all the basic instinct, and survival ability, which is primarily the basic function of the paleo-cortex, considered to be the location of the sub-consciousness… Neocortexologist
