When Good Drugs Go Bad

When Good Drugs Go Bad PDF Author: Dan Malleck
Publisher: UBC Press
ISBN: 0774829222
Category : History
Languages : en
Pages : 321

Get Book Here

Book Description
Throughout the 1800s, opium and cocaine could be easily obtained to treat a range of ailments in Canada. Dependency, when it occurred, was considered a matter of personal vice. Near the end of the century, attitudes shifted and access to drugs became more restricted. How did this happen? Dan Malleck examines the conditions that led to Canada’s current drug laws. Drawing on newspaper accounts, medical and pharmacy journals, professional association files, asylum documents, physicians’ case books, and pharmacy records, Malleck demonstrates how a number of social, economic, and cultural forces converged in the early 1900s to influence lawmakers and criminalize addiction. His research exposes how social concerns about drug addiction had less to do with the long pipe and shadowy den than with lobbying by medical professionals, a growing pharmaceutical industry, and concern about the morality and future of the nation.

When Good Drugs Go Bad

When Good Drugs Go Bad PDF Author: Dan Malleck
Publisher: UBC Press
ISBN: 0774829222
Category : History
Languages : en
Pages : 321

Get Book Here

Book Description
Throughout the 1800s, opium and cocaine could be easily obtained to treat a range of ailments in Canada. Dependency, when it occurred, was considered a matter of personal vice. Near the end of the century, attitudes shifted and access to drugs became more restricted. How did this happen? Dan Malleck examines the conditions that led to Canada’s current drug laws. Drawing on newspaper accounts, medical and pharmacy journals, professional association files, asylum documents, physicians’ case books, and pharmacy records, Malleck demonstrates how a number of social, economic, and cultural forces converged in the early 1900s to influence lawmakers and criminalize addiction. His research exposes how social concerns about drug addiction had less to do with the long pipe and shadowy den than with lobbying by medical professionals, a growing pharmaceutical industry, and concern about the morality and future of the nation.

When Good Drugs Go Bad

When Good Drugs Go Bad PDF Author: Dan Malleck
Publisher: UBC Press
ISBN: 9780774829212
Category : History
Languages : en
Pages : 320

Get Book Here

Book Description
In the 1800s, opium and cocaine could be easily obtained to treat a range of ailments. Drug dependency, when it occurred, was considered a matter of personal vice. Near the end of the century, attitudes shifted and access to drugs became more restricted. Dan Malleck reveals how different forces converged in the early 1900s to influence lawmakers and set the course for the drug laws that exist today. As this book shows, social concerns about drug addiction had less to do with the long pipe and shadowy den than with lobbying by medical professionals, concern about the morality and future of the nation, and a burgeoning pharmaceutical industry.

Drugs, Alcohol and Addiction in the Long Nineteenth Century

Drugs, Alcohol and Addiction in the Long Nineteenth Century PDF Author: Daniel Malleck
Publisher: Routledge
ISBN: 0429791313
Category : History
Languages : en
Pages : 2053

Get Book Here

Book Description
This collection captures key themes and issues in the broad history of addiction and vice in the Anglo-American world. Focusing on the long nineteenth-century, the volumes consider how scientific, social, and cultural experiences with drugs, alcohol, addiction, gambling, and prostitution varied around the world. What might be considered vice, or addiction could be interpreted in various ways, through various lenses, and such activities were interpreted differently depending upon the observer: the medical practitioner; the evangelical missionary; the thrill seeking bon-vivant, and the concerned government commissioner, to name but a few. For example, opium addiction in middle class households resulting from medical treatment was judged much differently than Chinese opium smoking by those in poverty or poor living conditions in North American work camps on the west coast, or on the streets of East London. This collection will assemble key documents representing both the official and general view of these various activities, providing readers with a cross section of interpretations and a solid grounding in the material that shaped policy change, cultural interpretation, and social action.

Corporatizing Canada

Corporatizing Canada PDF Author: Jamie Brownlee
Publisher: Between the Lines
ISBN: 1771133597
Category : Political Science
Languages : en
Pages : 421

Get Book Here

Book Description


Pleasure and Panic

Pleasure and Panic PDF Author: Dan Malleck
Publisher: UBC Press
ISBN: 077486754X
Category : History
Languages : en
Pages : 322

Get Book Here

Book Description
Booze, dope, smokes, and weed. Mind-altering, mood-changing substances have been part of human society for millennia. Pleasure and Panic reveals how attitudes toward drug and alcohol consumption have always been deeply embedded in cultural fears and social, political, and economic disparities. Contributors to this collection explore how drugs and alcohol intersect with diverse histories, including gender, medicine, popular culture, and business. Pleasure and Panic brings a dispassionate voice to current debates about liberalizing drug and alcohol laws and challenges existing ideas about how to deal with the so-called problems of drug and alcohol use.

Strange Trips

Strange Trips PDF Author: Lucas Richert
Publisher: McGill-Queen's Press - MQUP
ISBN: 0773556524
Category : Medical
Languages : en
Pages :

Get Book Here

Book Description
Examining the boundaries between recreational and medicinal drugs in the eyes of the public and the law.

Good Genes Gone Bad

Good Genes Gone Bad PDF Author: Narendra Chirmule
Publisher: Ebury Press
ISBN: 9780670096039
Category : Medical
Languages : en
Pages : 304

Get Book Here

Book Description
The field of biotechnology has evolved over the past four decades, developing medicines which are curing diseases. But this journey of success has been tough and arduous, built upon the shoulders of major failures. Good Genes Gone Bad highlights seven such colossal failures in drug development-all of which culminated in the development of novel drugs-weaving together various analogies through the stories and thus allowing the reader to understand complex biological phenomena. These stories include treatment of medical conditions such as genetic clotting disorder (haemophilia), childhood-diarrhoea (rotavirus vaccine), preventing HIV infection, activation of the immune systems to treat cancer, gene therapy for treatment of diseases caused by gene-defects/mutations, cell therapy for treatment of leukaemias, and finally the success of Biocon's approval of the first biologic drug for breast cancer. Written by the former R&D head of Biocon, India's largest pharmaceutical company, Good Genes Gone Bad is a fascinating look at the complex world of medicine and drug development, providing the readers with a sense of magnitude of challenges and the extent of difficulty that it takes to make novel medicines.

Adverse Drug Reactions

Adverse Drug Reactions PDF Author: Jack Uetrecht
Publisher: Springer Science & Business Media
ISBN: 3642006639
Category : Medical
Languages : en
Pages : 552

Get Book Here

Book Description
This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.

Pharmaceutical Data Mining

Pharmaceutical Data Mining PDF Author: Konstantin V. Balakin
Publisher: John Wiley & Sons
ISBN: 0470567619
Category : Medical
Languages : en
Pages : 584

Get Book Here

Book Description
Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.

Pharmacogenetics

Pharmacogenetics PDF Author: Wendell Weber
Publisher: Oxford University Press
ISBN: 0195341511
Category : Medical
Languages : en
Pages : 448

Get Book Here

Book Description
Genes are important modifiers of the human response to drugs, hormones, and toxins. Medical patients and healthy individuals alike display significant differences in response and suffer adverse effects as a result of exposure to many therapeutic agents and occupational chemicals. In this substantially revised second edition, highly regarded authority Wendell Weber brings together laboratory methods and epidemiologic studies in defining the role of heredity in human drug response. The book is divided into two major sections, one covering pharmacognetic concepts and the second the application of those concepts.