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Author: Henri Merle
Publisher:
ISBN:
Category :
Languages : fr
Pages : 251
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Author: Henri Merle
Publisher:
ISBN:
Category :
Languages : fr
Pages : 251
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Book Description
Author: Thomas Liehr
Publisher: Academic Press
ISBN: 0128235802
Category : Science
Languages : en
Pages : 430
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Book Description
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book's second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. - Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies - Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease - Features chapter contributions from international leaders in the field
Author: Jean-Jacques Kupiec
Publisher: World Scientific
ISBN: 981270499X
Category : Science
Languages : en
Pages : 274
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Book Description
In the 17th century, Descartes put forth the metaphor of the machine to explain the functioning of living beings. In the 18th century, La Mettrie extended the metaphor to man. The clock was then used as the paradigm of the machine. In the 20th century, this metaphor still held but the clock was replaced by a computer. Nowadays, the organism is viewed as a robot obeying signals emanating from a computer program controlled by genetic information. This book shows that such a conception leads to contradictions not only in the theory of biology but also in its experimental research program, thereby impeding its development. The analysis of this problem is based on the most recent experimental data obtained in molecular biology as well as the history and philosophy of biology. It shows that the machine theory did not succeed in breaking with Aristotle's finalism. The book presents a new approach to biological systems based on cellular Darwinism. Genes are ruled by probabilistic mechanisms allowing cells to differentiate stochastically. Embryo development is not governed by a determinist genetic program but by natural selection occurring among cell populations inside the organism. This theory has considerable philosophical consequences. Man may be a machine but he is a random one.
Author: Robert Lynn Carroll
Publisher: Cambridge University Press
ISBN: 9780521478090
Category : Science
Languages : en
Pages : 442
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Book Description
The factors that influenced the evolution of the vertebrates are compared with the importance of variation and selection that Darwin emphasised in this broad study of the patterns and forces of evolutionary change.
Author: Francis Rouessac
Publisher: John Wiley & Sons
ISBN: 1118681878
Category : Science
Languages : en
Pages : 494
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Book Description
Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail. Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques Maintains a careful balance between depth and breadth of coverage Includes examples, problems and their solutions Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis
Author: Janine M. Benyus
Publisher: Harper Collins
ISBN: 0061958921
Category : Science
Languages : en
Pages : 324
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Book Description
Repackaged with a new afterword, this "valuable and entertaining" (New York Times Book Review) book explores how scientists are adapting nature's best ideas to solve tough 21st century problems. Biomimicry is rapidly transforming life on earth. Biomimics study nature's most successful ideas over the past 3.5 million years, and adapt them for human use. The results are revolutionizing how materials are invented and how we compute, heal ourselves, repair the environment, and feed the world. Janine Benyus takes readers into the lab and in the field with maverick thinkers as they: discover miracle drugs by watching what chimps eat when they're sick; learn how to create by watching spiders weave fibers; harness energy by examining how a leaf converts sunlight into fuel in trillionths of a second; and many more examples. Composed of stories of vision and invention, personalities and pipe dreams, Biomimicry is must reading for anyone interested in the shape of our future.
Author: James K. Boyce
Publisher: John Wiley & Sons
ISBN: 1509526587
Category : Political Science
Languages : en
Pages : 71
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Book Description
The supreme challenge of our time is tackling climate change. We urgently need to curtail our use of fossil fuels – but how can we do so in a just and feasible way? In this compelling book, leading economist James Boyce shows that the key to solving this conundrum is to put a limit on carbon emissions, thereby raising the price of fossil fuels and generating strong incentives for clean energy. But there is a formidable hurdle: how do we secure broad public support for a policy that increases fuel costs for consumers? Boyce powerfully argues that carbon pricing can be made just and politically durable only if linked to returning the revenue to the public as carbon dividends. Founded on the principle that the gifts of nature belong to us all, not to corporations or governments, this bold reform could spark a twenty-first-century clean energy revolution. Essential reading for all concerned citizens, policy-makers, and students of public policy and environmental economics, this book will be a transformative contribution to one of the most important policy debates of our era.
Author:
Publisher: Academic Press
ISBN: 0124172016
Category : Science
Languages : en
Pages : 434
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Book Description
Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue. - Covers the area of genes and evolution - Contains invaluable contributions from an international board of authors - Provides a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes and epithelial tissue
Author: Ross J. MacIntyre
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 640
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Book Description
This volume in the Monographs in Evolutionary Biology series addresses issues that are part of an emerging area of research loosely called "mo lecular evolution. " Its practitioners include both molecular biologists cu rious about the evolutionary implications of their data and evolutionary biologists pushing their analyses to the molecular level. The union of these fields of molecular and organismal biology has been turbulent at times, and, as shall be seen, this dialectic has led to some very serious challenges to long-held notions about the role of natural selection in evolution and the economy of genome organization in eukaryotes. As an inevitable outgrowth of molecular biology, molecular evolution is necessarily a young discipline, but it can already point proudly to two major discoveries. The first, is the molecular clock, a concept that has emerged from the analysis of at least four data sets-amino acid sequences, immunologic data, DNA renaturation studies, and, recently, analyses of DNA sequences. The reality of a strong stochastic component in the evolution of nucleotide sequences can no longer be doubted, although the accuracy of the clock with regard to particular sequences and within particular groups of or ganisms should be independently measured each time it is used. Never theless, molecular clocks will assume increasingly important roles in phy logenetic reconstructions, especially since the fossil record is so fragmentary. The second major discovery of molecular evolution has been the incredible complexity of the eukaryotic genome.
Author: Joel Cracraft
Publisher:
ISBN: 9780231046923
Category : Evolution
Languages : en
Pages : 233
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Book Description
