Author: Maik J. Jornitz
Publisher: CRC Press
ISBN: 0849379547
Category : Medical
Languages : en
Pages : 816
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Book Description
Filtration and Purification in the Biopharmaceutical Industry, First Edition greatly expands its focus with extensive new material on the critical role of purification and the significant advances in filtration science and technology. This new edition provides state-of-the-science information on all aspects of filtration and purification, in
Author: Maik W. Jornitz
Publisher: CRC Press
ISBN: 1351675699
Category : Business & Economics
Languages : en
Pages : 673
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Book Description
Since sterile filtration and purification steps are becoming more prevalent and critical within medicinal drug manufacturing, the third edition of Filtration and Purification in the Biopharmaceutical Industry greatly expands its focus with extensive new material on the critical role of purification and advances in filtration science and technology. It provides state-of-the-science information on all aspects of bioprocessing including the current methods, processes, technologies and equipment. It also covers industry standards and regulatory requirements for the pharmaceutical and biopharmaceutical industries. The book is an essential, comprehensive source for all involved in filtration and purification practices, training and compliance. It describes such technologies as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration. Features: Addresses recent biotechnology-related processes and advanced technologies such as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration of medium, buffer and end product Presents detailed updates on the latest FDA and EMA regulatory requirements involving filtration and purification practices, as well as discussions on best practises in filter integrity testing Describes current industry quality standards and validation requirements and provides guidance for compliance, not just from an end-user perspective, but also supplier requirement It discusses the advantages of single-use process technologies and the qualification needs Sterilizing grade filtration qualification and process validation is presented in detail to gain the understanding of the regulatory needs The book has been compilated by highly experienced contributors in the field of pharmaceutical and biopharmaceutical processing. Each specific topic has been thoroughly examined by a subject matter expert.
Author: Kurt Brorson
Publisher:
ISBN: 9780939459230
Category :
Languages : en
Pages : 62
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Book Description
Author: C. Ray
Publisher: Springer Science & Business Media
ISBN: 940100479X
Category : Science
Languages : en
Pages : 262
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Book Description
Riverbank filtration is widely used in Europe and to some extent in the United States for the public water supply. It is a cost-effective and realisable treatment technology in which horizontal and vertical wells pump a mixture of ground water and induced surface water from a river. This book describes the biogeochemical issues involved in contaminant removal from surface water and the mechanisms of pathogen removal. Specifically, the following three points are considered: *The role of hydrogeological and well construction factors in the development of redox zones at bank filtration sites and the resulting impacts on contaminant removal. *The mechanisms of pathogen removal, including the processes, colloid filtration, die-away, decay, and predation. *The status of riverbank filtration processes in NATO partner countries.
Author:
Publisher: DIANE Publishing
ISBN: 1428900136
Category : Drinking water
Languages : en
Pages : 321
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Book Description
Author: Saurabh Gautam
Publisher: Springer Nature
ISBN: 3031284895
Category : Medical
Languages : en
Pages : 448
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Book Description
This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology.
Author: J. Brock McEwen
Publisher: American Water Works Association
ISBN: 0898678870
Category : Water
Languages : en
Pages : 392
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Book Description
Author: H. Murakami
Publisher: Springer Science & Business Media
ISBN: 9780792318828
Category : Science
Languages : en
Pages : 608
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Book Description
New data on animal cell technology are brought together in this volume, with emphasis given to the basic characterization of cell lines. The merits of different cell culture systems are examined and investigations into the factors influencing cell growth and productivity are presented. A special section deals with the biological properties of proteins produced by engineered animal cells. All those involved in the culture of animal cells will find this volume invaluable.
Author: Uwe Gottschalk
Publisher: John Wiley & Sons
ISBN: 1119126924
Category : Medical
Languages : en
Pages : 755
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Book Description
Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing
Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527340637
Category : Science
Languages : en
Pages : 628
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Book Description
This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.
