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Author: James Sneyd
Publisher: Springer Science & Business Media
ISBN: 9783540254393
Category : Mathematics
Languages : en
Pages : 228
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Book Description
This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of cell types. Calcium plays a crucial role in cell physiology, and the study of its dynamics lends insight into many different cellular processes. In particular, calcium plays a central role in muscular contraction, olfactory transduction and synaptic communication, three of the topics to be addressed in detail in this book. In addition to the models, much of the underlying physiology is presented, so that readers may learn both the mathematics and the physiology, and see how the models are applied to specific biological questions. It is intended primarily as a graduate text or a research reference. It will serve as a concise and up-to-date introduction to all those who wish to learn about the state of calcium dynamics modeling, and how such models are applied to physiological questions.
Author: James Sneyd
Publisher: Springer Science & Business Media
ISBN: 9783540254393
Category : Mathematics
Languages : en
Pages : 228
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Book Description
This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of cell types. Calcium plays a crucial role in cell physiology, and the study of its dynamics lends insight into many different cellular processes. In particular, calcium plays a central role in muscular contraction, olfactory transduction and synaptic communication, three of the topics to be addressed in detail in this book. In addition to the models, much of the underlying physiology is presented, so that readers may learn both the mathematics and the physiology, and see how the models are applied to specific biological questions. It is intended primarily as a graduate text or a research reference. It will serve as a concise and up-to-date introduction to all those who wish to learn about the state of calcium dynamics modeling, and how such models are applied to physiological questions.
Author: Avner Friedman
Publisher: Springer
ISBN: 3540324151
Category : Mathematics
Languages : en
Pages : 254
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Book Description
This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretes growth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models the interaction between a tumor and the immune system. Chapter 5 is concerned with chemotherapy; it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6 reviews mathematical results for various cancer models.
Author:
Publisher:
ISBN:
Category : Biomathematics
Languages : en
Pages : 232
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Book Description
Author: Alla Borisyuk
Publisher: Springer Science & Business Media
ISBN: 9783540238584
Category : Mathematics
Languages : en
Pages : 184
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Book Description
This volume introduces some basic theories on computational neuroscience. Chapter 1 is a brief introduction to neurons, tailored to the subsequent chapters. Chapter 2 is a self-contained introduction to dynamical systems and bifurcation theory, oriented towards neuronal dynamics. The theory is illustrated with a model of Parkinson's disease. Chapter 3 reviews the theory of coupled neural oscillators observed throughout the nervous systems at all levels; it describes how oscillations arise, what pattern they take, and how they depend on excitory or inhibitory synaptic connections. Chapter 4 specializes to one particular neuronal system, namely, the auditory system. It includes a self-contained introduction, from the anatomy and physiology of the inner ear to the neuronal network that connects the hair cells to the cortex, and describes various models of subsystems.
Author:
Publisher:
ISBN:
Category : Biomathematics
Languages : en
Pages :
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Book Description
Author: Brian P. Ingalls
Publisher: MIT Press
ISBN: 0262545829
Category : Science
Languages : en
Pages : 423
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Book Description
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Avner Friedman
Publisher: Springer
ISBN: 3540743316
Category : Mathematics
Languages : en
Pages : 215
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Book Description
This book offers an introduction to fast growing research areas in evolution of species, population genetics, ecological models, and population dynamics. It reviews the concept and methodologies of phylogenetic trees, introduces ecological models, examines a broad range of ongoing research in population dynamics, and deals with gene frequencies under the action of migration and selection. The book features computational schemes, illustrations, and mathematical theorems.
Author: Bei Hu
Publisher: Springer Science & Business Media
ISBN: 3642184596
Category : Mathematics
Languages : en
Pages : 137
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Book Description
There is an enormous amount of work in the literature about the blow-up behavior of evolution equations. It is our intention to introduce the theory by emphasizing the methods while seeking to avoid massive technical computations. To reach this goal, we use the simplest equation to illustrate the methods; these methods very often apply to more general equations.
Author: Katharina Habermann
Publisher: Springer
ISBN: 3540334211
Category : Mathematics
Languages : en
Pages : 131
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Book Description
This volume is the first one that gives a systematic and self-contained introduction to the theory of symplectic Dirac operators and reflects the current state of the subject. At the same time, it is intended to establish the idea that symplectic spin geometry and symplectic Dirac operators may give valuable tools in symplectic geometry and symplectic topology, which have become important fields and very active areas of mathematical research.
