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Author: Y. W. Loke
Publisher: Cambridge University Press
ISBN: 9780521441933
Category : Medical
Languages : en
Pages : 332
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Book Description
This book explains and reviews some of the significant events involved in human implantation and the establishment of the placenta in the uterus. This critical phase in human reproduction has proved to be an elusive and challenging area of research, not least because of the immunological and genetic interactions between the mother and fetus. The volume focuses on the most recent advances in our understanding of the basic mechanisms involved, with a particular emphasis on cell biology and immunology. This lucid volume will benefit all those studying and undertaking research in reproductive biology and immunology, perinatal pathology, fetal medicine and obstetrics.
Author: Y. W. Loke
Publisher: Cambridge University Press
ISBN: 9780521441933
Category : Medical
Languages : en
Pages : 332
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Book Description
This book explains and reviews some of the significant events involved in human implantation and the establishment of the placenta in the uterus. This critical phase in human reproduction has proved to be an elusive and challenging area of research, not least because of the immunological and genetic interactions between the mother and fetus. The volume focuses on the most recent advances in our understanding of the basic mechanisms involved, with a particular emphasis on cell biology and immunology. This lucid volume will benefit all those studying and undertaking research in reproductive biology and immunology, perinatal pathology, fetal medicine and obstetrics.
Author: Gernot Desoye
Publisher:
ISBN:
Category : Placenta
Languages : en
Pages : 122
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Book Description
Author: H.W. Denker
Publisher: Springer Science & Business Media
ISBN: 1461306159
Category : Medical
Languages : en
Pages : 455
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Book Description
Interest in mechanisms of embryo implantation is increasing, particularly with the realization that failure of implantation after in vitro fertilization and embryo transfer places significant limits on the success of treatment. In addition, there is a need to provide hypotheses, and ultimately mechanisms, for the high rates of embryonic loss in women in the population at large. Traditionally, implantation research has concentrated on genetics and endocrinology without providing many therapeutic benefits. A new era is now beginning with the application of modem cellular and molecular approaches to the investigation of the relationship between trophoblast and endometrium. At the same time, older data can be reevaluated in the light of current research into cell cell and cell-matrix interactions. The feeling that new avenues of research are open was apparent when an international group of scientists came together at a workshop on "The Cell Biology of Trophoblast Invasion In Vivo and In Vitro" held during the XXIV Annual Meeting of the Cell, Tissue and Organ Culture Study Group (C.T.O.C.) at Heidelberg in 1986. What was unusual about this Conference was the interdisciplinary dialogue between implantation researchers and tumor biologists, highlighting aspects common to invasion of trophoblast and tumor cells.
Author: Michael J. Soares
Publisher: Springer Science & Business Media
ISBN: 1592599893
Category : Medical
Languages : en
Pages : 457
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Book Description
The aim of the two-volume set of Placenta and Trophoblast: Methods and Protocols is to offer contemporary approaches for studying the biology of the placenta. The chapters contained herein also address critical features of the female organ within which the embryo is housed, the uterus, and some aspects of the embryo–fetus itself, particularly those of common experimental animal models. In keeping with the organization used effectively in other volumes in this series, each chapter has a brief introduction followed by a list of required items, protocols, and notes designed to help the reader perform the expe- ments without difficulty. In both volumes, sources of supplies are given and illustrations highlight particular techniques as well as expected outcomes. A key aspect of these volumes is that the contributors are at the forefronts of their disciplines, thus ensuring the accuracy and usefulness of the chapters. Placenta research has progressed rapidly over the past several decades by taking advantage of the technical advances made in other fields. For example, the reader will note that many techniques, such as reverse transcriptase po- merase chain reaction, northern and western blotting, microarray analyses and in situ hybridization experiments, are routinely used for dissecting a wide range of experimental questions. Protein analysis and functional experiments on tissues and cells that comprise the maternal–fetal interface benefit from studies in en- crinology, immunology, and developmental biology. These volumes also present new ideas on investigating gene imprinting and gene transfer via viral vectors.
Author: Robert Geoffrey Edwards
Publisher: CUP Archive
ISBN: 9780521206365
Category : Health & Fitness
Languages : en
Pages : 304
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Book Description
Author: Donald W. Morrish
Publisher: University Rochester Press
ISBN: 9781580460323
Category : Medical
Languages : en
Pages : 432
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Book Description
This work, the 11th Volume of Trophoblast Research series, comprises collected papers presented to the 13th Rochester Trophoblast Conference (Summer 1996), held for the first time at Banff, Alberta, Canada. This edited volume hopes to recreate the main scientific themes discussed at this meeting for the reader. Established in 1961, the Rochester Trophoblast Conference is the oldest international conference on the placenta, and it became a formal corporate member of the International Federation of Placental Associations at the Banff conference.
Author: Ashley Moffett
Publisher: Cambridge University Press
ISBN: 1139452541
Category : Medical
Languages : en
Pages : 246
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Book Description
Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.
Author: Hans-Werner Denker
Publisher:
ISBN:
Category :
Languages : en
Pages : 462
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Book Description
Author: Ronald A. Pattillo
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 528
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Book Description
Through the cooperation of the University of Nairobi Medical School and Kenyatta National Hospital, the International Society for the Study of Trophoblast Disease brought together scientists and clinicians from all continents to discuss epidemiology, etiology, immunobiology, clinical diagnosis, and chemotherapy of trophoblast neoplasms. The intent of this book is to provide a broad perspective to neoplasms of the human trophoblast. Since the majority of the chapters contain data presented at the First World Congress in Nairobi, there is clear emphasis on epidemiology and clinical treatment of trophoblast disease around the world. While these two topics are probably the highlights of the book, there has been a deliberate effort to include chapters on etiology, genetic origin, and immunology of trophoblast disease.
Author: Gil Mor
Publisher: Academic Press
ISBN: 0128189304
Category : Medical
Languages : en
Pages : 462
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Book Description
Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs. Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus Evaluates each immune cell type and its function during specific reproductive events Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series
