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Author: Kristina Kelly
Publisher:
ISBN: 9781956037203
Category :
Languages : en
Pages : 0
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Book Description
Author: Kristina Kelly
Publisher:
ISBN: 9781956037203
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Steven Piantadosi
Publisher: John Wiley & Sons
ISBN: 1394195672
Category : Mathematics
Languages : en
Pages : 789
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Book Description
Clinical Trials Comprehensive resource presenting methods essential in planning, designing, conducting, analyzing, and interpreting clinical trials The Fourth Edition of Clinical Trials builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials, discussing principles of design for various types of clinical trials and elements of planning the experiment, assembling a study cohort, assessing data, and reporting results. Each chapter contains an introduction and summary to reinforce key points. Discussion questions stimulate critical thinking and help readers understand how they can apply their newfound knowledge. Written by a highly qualified author with significant experience in the field, the Fourth Edition of Clinical Trials approaches the topic with: Problems that may arise during a trial, and accompanying common sense solutions Design alternatives for addressing many questions in therapeutic development Statistical principles with new and provocative topics, such as generalizing results, operating characteristics, trial issues during the COVID-19 pandemic, and more Alternative medicine, ethics, middle development, comparative studies, adaptive designs, and clinical trials using point of care data Revamped exercise sets, updated and extensive references, new material on endpoints and the developmental pipeline, and revisions of numerous sections, tables, and figures Standing out due to its accessible and broad coverage of statistical design methods which are the building blocks of clinical trials and medical research, Clinical Trials is an essential learning aid on the subject for undergraduate and graduate clinical trials courses.
Author: Byron Jones
Publisher: CRC Press
ISBN: 1439861420
Category : Mathematics
Languages : en
Pages : 440
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Book Description
Design and Analysis of Cross-Over Trials is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture. The first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new Third Edition: Contains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power Employs the R package Crossover, specially created to accompany the book and provide a graphical user interface for locating designs in a large catalog and for searching for new designs Includes updates regarding the use of period baselines and the analysis of data from very small trials Reflects the availability of new procedures in SAS, particularly proc glimmix Presents the SAS procedure proc mcmc as an alternative to WinBUGS for Bayesian analysis Complete with real data and downloadable SAS code, Design and Analysis of Cross-Over Trials, Third Edition provides a practical understanding of the latest methods along with the necessary tools for implementation.
Author: Bruce B. Whitman
Publisher:
ISBN: 9780988205239
Category : Jury
Languages : en
Pages : 177
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Book Description
The most important people in any courtroom are the jurors. Unfortunately, jurors are often hiding from the lawyers, knowingly or unconsciously repressing their innermost feelings. This repression, unexposed, can doom even the best cases and lawyers to defeat. With more than 30 years of experience in front of juries, Whitman explains how to use proven psychological and psychiatric principles and methods in the courtroom to lead the jury to a verdict and damage award for the plaintiff. He explains how such principles as transference, positive regard, unity, group dynamics, and humanism can overcome natural juror resistance to awarding large ? or even small ? damages and verdicts. He explains how to incorporate the strategies of respected trial scientists, such as David Ball ("Damages") and Rick Friedman ("Rules of the Road"), into his own psychology-based methods to maximize the chance of success in the courtroom. Whitman's thesis is that instead of focusing on their own performance and inner struggles, the most successful trial lawyers concentrate on what the jurors need from the lawyer and how the jury perceives the trial.
Author: Byron Jones
Publisher: CRC Press
ISBN: 1420036092
Category : Mathematics
Languages : en
Pages : 390
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Book Description
The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.
Author: Scott Benner
Publisher: Spry Publishing
ISBN: 1938170164
Category : Family & Relationships
Languages : en
Pages : 111
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Book Description
2013 Mom's Choice Awards® Winner MEN: Ever wonder about stay-at-home dads? What in the name of testosterone do they DO all day with those kids? I mean, are they really men at all, or are they some strange, invasive alien species, sent to Earth to defy and destroy all gender stereotypes?. WOMEN: Ever dream about stay-at-home dads? Do they really wash clothes, pick up after themselves, take great care of your kids, and have dinner waiting for you when you get home? There must be horrible, secret downside that they don’t warn you about, right?. Life Is Short, Laundry Is Eternal provides a rare glimpse into the natural habitat of this most mysterious and splendid of creatures, the North American Stay-at-Home Father (Paternus domesticus). Learn what motivates a man to pursue this noble occupation. Discover the countless joys and periodic sorrows that come with raising a family.. Witness the life and family of Scott Benner, author, activist, humorist, and 12-year stay-at-home dad. When Scott’s daughter, Arden, was diagnosed with type 1 diabetes at the age of two, his world took a sharp turn, but his positive outlook on life did not waver.. Scott’s colloquial wisdom will warm your heart while it challenges your ideas about parenting and gender roles in today’s household. Written from a truly unique point of view in a style both poignant and playful, Life Is Short, Laundry Is Eternal is an honest portrait of the modern family.
Author: Carlo Umiltà
Publisher: MIT Press
ISBN: 9780262210126
Category : Medical
Languages : en
Pages : 978
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Book Description
During the past decade, evidence of dissociation between conscious and nonconscious information processing has emerged from the study of normal subjects and brain damaged patients. The thirty-five original contributions in this book cover the latest work on this important topic. During the past decade, evidence of dissociation between conscious and nonconscious information processing has emerged from the study of normal subjects and brain damaged patients. The thirty-five original contributions in this book cover the latest work on this important topic across such traditional areas of research as vision, face recognition, spatial attention, control processes, semantic memory, episodic memory, and learning. Each section is introduced by an overview chapter that presents and evaluates the available empirical evidence in a given area and is followed by several experimental papers. The book opens with the Association Lecture, by George Mandler, "On Remembering without Really Trying: Hypermnesia, Incubation, and Mind Popping."
Author: Jeffrey Frank
Publisher: Simon and Schuster
ISBN: 1501102907
Category : Biography & Autobiography
Languages : en
Pages : 576
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Book Description
Jeffrey Frank, author of the bestselling Ike and Dick, returns with the “beguiling” (The New York Times) first full account of the Truman presidency in nearly thirty years, recounting how a seemingly ordinary man met the extraordinary challenge of leading America through the pivotal years of the mid-20th century. The nearly eight years of Harry Truman’s presidency—among the most turbulent in American history—were marked by victory in the wars against Germany and Japan; the first use of an atomic bomb and the development of far deadlier weapons; the start of the Cold War and the creation of the NATO alliance; the Marshall Plan to rebuild the wreckage of postwar Europe; the Red Scare; and the fateful decision to commit troops to fight a costly “limited war” in Korea. Historians have tended to portray Truman as stolid and decisive, with a homespun manner, but the man who emerges in The Trials of Harry S. Truman is complex and surprising. He believed that the point of public service was to improve the lives of one’s fellow citizens and fought for a national health insurance plan. While he was disturbed by the brutal treatment of African Americans and came to support stronger civil rights laws, he never relinquished the deep-rooted outlook of someone with Confederate ancestry reared in rural Missouri. He was often carried along by the rush of events and guided by men who succeeded in refining his fixed and facile view of the postwar world. And while he prided himself on his Midwestern rationality, he could act out of instinct and combativeness, as when he asserted a president’s untested power to seize the nation’s steel mills. The Truman who emerges in these pages is a man with generous impulses, loyal to friends and family, and blessed with keen political instincts, but insecure, quick to anger, and prone to hasty decisions. Archival discoveries, and research that led from Missouri to Washington, Berlin and Korea, have contributed to an indelible and “intimate” (The Washington Post) portrait of a man, born in the 19th century, who set the nation on a course that reverberates in the 21st century, a leader who never lost a schoolboy’s love for his country and its Constitution.
Author: Woodrow Michael Kroll
Publisher: Wipf and Stock Publishers
ISBN:
Category : Religion
Languages : en
Pages : 311
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Book Description
No event in the history of humankind has elicited more comment or sparked more controversy than the trials, crucifixion, and burial of Jesus of Nazareth. The Trials, Crucifixion, and Burial of Jesus of Nazareth investigates each of these events in much detail from the historical, archaeological, theological, geographical, and biblical viewpoints. The book distinguishes between the late-night, hurriedly called meeting of a quorum of Sanhedrin members and the official meeting in the Chamber of Hewn Stone the next morning. It examines the ten charges made against Jesus and why they changed so often throughout his trial. It also investigates the twenty-five obvious irregularities from Jewish law that were evident in Jesus’ trial. Explored is the legitimacy of applying Mishnaic law to a first-century trial. Every suggested location for the trial and crucifixion of the Master is explored along with the question “Did Jesus really die, and does it matter?” Finally, a complete inventory of Jesus’ physical, emotional, and spiritual suffering between Gethsemane and Golgotha is provided along with appropriate comments. This book is something of a one-stop shop for all things related to the trials, crucifixion, and burial of Jesus.
Author: George H. Hodos
Publisher: Bloomsbury Publishing USA
ISBN: 0313045917
Category : Law
Languages : en
Pages : 214
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Book Description
Show Trials combines first-hand knowledge with hitherto unpublished, confidential material, to offer a penetrating and candid account of the Stalinist purges that occurred in Albanian, East German, Bulgarian, and Rumanian purges, as well as in Hungary, Czechoslovakia, and Poland. George Hodos shows how these trials played a pivotal role in consolidating Soviet domination over the satellite countries during Stalin's lifetime. As an important addition to our understanding of these events and times, Show Trials is essential for historians of Eastern Europe and absorbing reading for anyone interested in world affairs.
