Author: Georgios P. D. Argyropoulos
Publisher: Springer Nature
ISBN: 3030356876
Category : Medical
Languages : en
Pages : 300
Book Description
This book provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative brain abnormalities on speech and language. To this end, this edited volume brings together contributions from several leading experts in a markedly broad range of disciplines, comprising Neurology, Neurosurgery, Genetics, Engineering, Neuroimaging and Neurostimulation, Neuropsychology, and Speech and Language Therapy.
Translational Neuroscience of Speech and Language Disorders
Translational Neuroscience
Author: Karoly Nikolich
Publisher: MIT Press
ISBN: 0262029863
Category : Medical
Languages : en
Pages : 319
Book Description
Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig
Publisher: MIT Press
ISBN: 0262029863
Category : Medical
Languages : en
Pages : 319
Book Description
Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig
Conn's Translational Neuroscience
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0128025964
Category : Medical
Languages : en
Pages : 778
Book Description
Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment
Publisher: Academic Press
ISBN: 0128025964
Category : Medical
Languages : en
Pages : 778
Book Description
Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment
Animal Models of Speech and Language Disorders
Author: Santosh A. Helekar
Publisher: Springer Science & Business Media
ISBN: 1461484006
Category : Medical
Languages : en
Pages : 301
Book Description
Basic research over the last decade or two has uncovered similarities between speech, especially its sensori-motor aspects, and vocal communication in several non-human species. The most comprehensive studies so far have been conducted in songbirds. Songbirds offer us a model system to study the interactions between developmental or genetic predispositions and tutor-dependent influences, on the learning of vocal communication. Songbird research has elucidated cellular and molecular mechanisms underlying learning and production of vocal patterns, perception of vocal sounds, vocal motor control and vocal neuromotor plasticity. More recently, the entire genome of the songbird zebra finch has been sequenced. These discoveries, along with the identification of several genes implicated in familial human speech and language disorders, have made it possible to look for analogues of speech and language dysfunction in zebra finches, at least at the perceptual and sensori-motor levels. Two approaches in particular have led us closer to the development of animal models of human speech conditions, namely developmental stuttering and a familial verbal dyspraxia associated with a mutation in the gene for the transcription factor FoxP2. Work on other animals that show developmental sensori-motor learning of vocal sounds used for communication have also shown significant progress, leading to the possibility of development of models of speech and language dysfunction in them. Among mammals, the principal ones include dolphins and whales. In non-human primates, while vocal learning per se is not very prominent, investigations on their communicative abilities have thrown some light on the rudiments of language. These considerations make the publication of a book focused on animal models of speech and language disorders, detailing the overall investigative approach of neurobehavioral studies in animals capable of vocal communication and learned vocalizations, a much-needed and worthwhile project. It would serve as a unifying review of research in this new multidisciplinary frontier, spanning the molecular to the behavioral, for clinicians and researchers, as well as a teaching resource for advanced speech pathology and neuroscience students. This book will also be the first of its kind.
Publisher: Springer Science & Business Media
ISBN: 1461484006
Category : Medical
Languages : en
Pages : 301
Book Description
Basic research over the last decade or two has uncovered similarities between speech, especially its sensori-motor aspects, and vocal communication in several non-human species. The most comprehensive studies so far have been conducted in songbirds. Songbirds offer us a model system to study the interactions between developmental or genetic predispositions and tutor-dependent influences, on the learning of vocal communication. Songbird research has elucidated cellular and molecular mechanisms underlying learning and production of vocal patterns, perception of vocal sounds, vocal motor control and vocal neuromotor plasticity. More recently, the entire genome of the songbird zebra finch has been sequenced. These discoveries, along with the identification of several genes implicated in familial human speech and language disorders, have made it possible to look for analogues of speech and language dysfunction in zebra finches, at least at the perceptual and sensori-motor levels. Two approaches in particular have led us closer to the development of animal models of human speech conditions, namely developmental stuttering and a familial verbal dyspraxia associated with a mutation in the gene for the transcription factor FoxP2. Work on other animals that show developmental sensori-motor learning of vocal sounds used for communication have also shown significant progress, leading to the possibility of development of models of speech and language dysfunction in them. Among mammals, the principal ones include dolphins and whales. In non-human primates, while vocal learning per se is not very prominent, investigations on their communicative abilities have thrown some light on the rudiments of language. These considerations make the publication of a book focused on animal models of speech and language disorders, detailing the overall investigative approach of neurobehavioral studies in animals capable of vocal communication and learned vocalizations, a much-needed and worthwhile project. It would serve as a unifying review of research in this new multidisciplinary frontier, spanning the molecular to the behavioral, for clinicians and researchers, as well as a teaching resource for advanced speech pathology and neuroscience students. This book will also be the first of its kind.
Translational Speech-Language Pathology and Audiology
Author: Robert Goldfarb
Publisher: Plural Publishing
ISBN: 159756690X
Category : Medical
Languages : en
Pages : 393
Book Description
Publisher: Plural Publishing
ISBN: 159756690X
Category : Medical
Languages : en
Pages : 393
Book Description
Learning Disabilities
Author: Sandro Misciagna
Publisher: BoD – Books on Demand
ISBN: 1839685875
Category : Education
Languages : en
Pages : 384
Book Description
Learning disabilities are a heterogeneous group of disorders characterized by failure to acquire, retrieve, and use information competently. These disorders have a multifactorial aetiology and are most common and severe in children, especially when comorbid with other chronic health conditions. This book provides current and comprehensive information about learning disorders, including information on neurobiology, assessment, clinical features, and treatment. Chapters cover such topics as historical research and hypotheses of learning disorders, neuropsychological assessment and counselling, characteristics of specific disorders such as autism and ADHD, evidence-based treatment strategies and assistive technologies, and much more.
Publisher: BoD – Books on Demand
ISBN: 1839685875
Category : Education
Languages : en
Pages : 384
Book Description
Learning disabilities are a heterogeneous group of disorders characterized by failure to acquire, retrieve, and use information competently. These disorders have a multifactorial aetiology and are most common and severe in children, especially when comorbid with other chronic health conditions. This book provides current and comprehensive information about learning disorders, including information on neurobiology, assessment, clinical features, and treatment. Chapters cover such topics as historical research and hypotheses of learning disorders, neuropsychological assessment and counselling, characteristics of specific disorders such as autism and ADHD, evidence-based treatment strategies and assistive technologies, and much more.
Speech Perception, Production and Acquisition
Author: Huei‐Mei Liu
Publisher: Springer Nature
ISBN: 9811576068
Category : Foreign Language Study
Languages : en
Pages : 277
Book Description
This book addresses important issues of speech processing and language learning in Chinese. It highlights perception and production of speech in healthy and clinical populations and in children and adults. This book provides diverse perspectives and reviews of cutting-edge research in past decades on how Chinese speech is processed and learned. Along with each chapter, future research directions have been discussed. With these unique features and the broad coverage of topics, this book appeals to not only scholars and students who study speech perception in preverbal infants and in children and adults learning Chinese, but also to teachers with interests in pedagogical applications in teaching Chinese as Second Language.
Publisher: Springer Nature
ISBN: 9811576068
Category : Foreign Language Study
Languages : en
Pages : 277
Book Description
This book addresses important issues of speech processing and language learning in Chinese. It highlights perception and production of speech in healthy and clinical populations and in children and adults. This book provides diverse perspectives and reviews of cutting-edge research in past decades on how Chinese speech is processed and learned. Along with each chapter, future research directions have been discussed. With these unique features and the broad coverage of topics, this book appeals to not only scholars and students who study speech perception in preverbal infants and in children and adults learning Chinese, but also to teachers with interests in pedagogical applications in teaching Chinese as Second Language.
The Science-Music Borderlands
Author: Elizabeth H. Margulis
Publisher: MIT Press
ISBN: 0262373033
Category : Music
Languages : en
Pages : 429
Book Description
Interdisciplinary essays on music psychology that integrate scientific, humanistic, and artistic ways of knowing in transformative ways. Researchers using scientific methods and approaches to advance our understanding of music and musicality have not yet grappled with some of the perils that humanistic fields concentrating on music have long articulated. In this edited volume, established and emerging researchers—neuroscientists and cognitive scientists, musicians, historical musicologists, and ethnomusicologists—build bridges between humanistic and scientific approaches to music studies, particularly music psychology. Deftly edited by Elizabeth H. Margulis, Psyche Loui, and Deirdre Loughridge, The Science-Music Borderlands embodies how sustained interaction among disciplines can lead to a richer understanding of musical life. The essays in this volume provide the scientific study of music with its first major reckoning, exploring the intellectual history of the field and its central debates, while charting a path forward. The Science-Music Borderlands is essential reading for music scholars from any disciplinary background. It will also interest those working at the intersection of music and science, such as music teachers, performers, composers, and music therapists. Contributors: Manuel Anglada-Tort, Salwa El-Sawan Castelo-Branco, Hu Chuan-Peng, Laura K. Cirelli, Alexander W. Cowan, Jonathan De Souza, Diana Deutsch, Diandra Duengen, Sarah Faber, Steven Feld, Shinya Fujii, Assal Habibi, Erin. E. Hannon, Shantala Hegde, Beatriz Ilari, Jason Jabbour, Nori Jacoby, Haley E. Kragness, Grace Leslie, Casey Lew-Williams, Deirdre Loughridge, Psyche Loui, Diana Mangalagiu, Elizabeth H. Margulis, Randy McIntosh, Rita McNamara, Eduardo Reck Miranda, Daniel Müllensiefen, Rachel Mundy, Florence Ewomazino Nweke, Patricia Opondo, Aniruddh D. Patel, Andrea Ravignani, Carmel Raz, Matthew Sachs, Marianne Sarfati, Patrick E. Savage, Huib Schippers, Jim Sykes, Gary Tomlinson, Jamal Williams, Maria A. G. Witek, Pamela Z
Publisher: MIT Press
ISBN: 0262373033
Category : Music
Languages : en
Pages : 429
Book Description
Interdisciplinary essays on music psychology that integrate scientific, humanistic, and artistic ways of knowing in transformative ways. Researchers using scientific methods and approaches to advance our understanding of music and musicality have not yet grappled with some of the perils that humanistic fields concentrating on music have long articulated. In this edited volume, established and emerging researchers—neuroscientists and cognitive scientists, musicians, historical musicologists, and ethnomusicologists—build bridges between humanistic and scientific approaches to music studies, particularly music psychology. Deftly edited by Elizabeth H. Margulis, Psyche Loui, and Deirdre Loughridge, The Science-Music Borderlands embodies how sustained interaction among disciplines can lead to a richer understanding of musical life. The essays in this volume provide the scientific study of music with its first major reckoning, exploring the intellectual history of the field and its central debates, while charting a path forward. The Science-Music Borderlands is essential reading for music scholars from any disciplinary background. It will also interest those working at the intersection of music and science, such as music teachers, performers, composers, and music therapists. Contributors: Manuel Anglada-Tort, Salwa El-Sawan Castelo-Branco, Hu Chuan-Peng, Laura K. Cirelli, Alexander W. Cowan, Jonathan De Souza, Diana Deutsch, Diandra Duengen, Sarah Faber, Steven Feld, Shinya Fujii, Assal Habibi, Erin. E. Hannon, Shantala Hegde, Beatriz Ilari, Jason Jabbour, Nori Jacoby, Haley E. Kragness, Grace Leslie, Casey Lew-Williams, Deirdre Loughridge, Psyche Loui, Diana Mangalagiu, Elizabeth H. Margulis, Randy McIntosh, Rita McNamara, Eduardo Reck Miranda, Daniel Müllensiefen, Rachel Mundy, Florence Ewomazino Nweke, Patricia Opondo, Aniruddh D. Patel, Andrea Ravignani, Carmel Raz, Matthew Sachs, Marianne Sarfati, Patrick E. Savage, Huib Schippers, Jim Sykes, Gary Tomlinson, Jamal Williams, Maria A. G. Witek, Pamela Z
Handbook of the Neuroscience of Language
Author: Brigitte Stemmer
Publisher: Academic Press
ISBN: 0080564917
Category : Language Arts & Disciplines
Languages : en
Pages : 505
Book Description
In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic questions, whereas today it constitutes a routine component. At the same time there have been significant developments in linguistic and psychological theory that speak to the neuroscience of language. This book consolidates those advances into a single reference. The Handbook of the Neuroscience of Language provides a comprehensive overview of this field. Divided into five sections, section one discusses methods and techniques including clinical assessment approaches, methods of mapping the human brain, and a theoretical framework for interpreting the multiple levels of neural organization that contribute to language comprehension. Section two discusses the impact imaging techniques (PET, fMRI, ERPs, electrical stimulation of language cortex, TMS) have made to language research. Section three discusses experimental approaches to the field, including disorders at different language levels in reading as well as writing and number processing. Additionally, chapters here present computational models, discuss the role of mirror systems for language, and cover brain lateralization with respect to language. Part four focuses on language in special populations, in various disease processes, and in developmental disorders. The book ends with a listing of resources in the neuroscience of language and a glossary of items and concepts to help the novice become acquainted with the field. Editors Stemmer & Whitaker prepared this book to reflect recent developments in neurolinguistics, moving the book squarely into the cognitive neuroscience of language and capturing the developments in the field over the past 7 years. - History section focuses on topics that play a current role in neurolinguistics research, aphasia syndromes, and lesion analysis - Includes section on neuroimaging to reflect the dramatic changes in methodology over the past decade - Experimental and clinical section reflects recent developments in the field
Publisher: Academic Press
ISBN: 0080564917
Category : Language Arts & Disciplines
Languages : en
Pages : 505
Book Description
In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic questions, whereas today it constitutes a routine component. At the same time there have been significant developments in linguistic and psychological theory that speak to the neuroscience of language. This book consolidates those advances into a single reference. The Handbook of the Neuroscience of Language provides a comprehensive overview of this field. Divided into five sections, section one discusses methods and techniques including clinical assessment approaches, methods of mapping the human brain, and a theoretical framework for interpreting the multiple levels of neural organization that contribute to language comprehension. Section two discusses the impact imaging techniques (PET, fMRI, ERPs, electrical stimulation of language cortex, TMS) have made to language research. Section three discusses experimental approaches to the field, including disorders at different language levels in reading as well as writing and number processing. Additionally, chapters here present computational models, discuss the role of mirror systems for language, and cover brain lateralization with respect to language. Part four focuses on language in special populations, in various disease processes, and in developmental disorders. The book ends with a listing of resources in the neuroscience of language and a glossary of items and concepts to help the novice become acquainted with the field. Editors Stemmer & Whitaker prepared this book to reflect recent developments in neurolinguistics, moving the book squarely into the cognitive neuroscience of language and capturing the developments in the field over the past 7 years. - History section focuses on topics that play a current role in neurolinguistics research, aphasia syndromes, and lesion analysis - Includes section on neuroimaging to reflect the dramatic changes in methodology over the past decade - Experimental and clinical section reflects recent developments in the field
Translational Speech-language Pathology and Audiology
Author: Robert M. Goldfarb
Publisher: Plural Publishing
ISBN: 9781597564458
Category : Audiology
Languages : en
Pages : 0
Book Description
Translational research has been present and ongoing for decades and yet, in spite of The National Institutes of Health promoting this "bench-to-bedside" approach since 2006, its adoption by the professions of speech-language pathology and audiology has been relatively scant and mostly individually approached. Although efforts have been made in this direction by individuals, the communication sciences and disorders professions are somewhat behind the curve in not addressing this issue directly.. For practicing clinicians, researchers, and students taking research seminars, Translational Speech-Language Pathology and Audiology examines the broad fields of laboratory, clinical, and public health research. Interdisciplinary and cross-disciplinary in scope, it aims to expedite the translation of related discoveries into new and improved standards of care. This series of short essays also honors Dr. Sadanand Singh, the late CEO and Founder of Plural Publishing, Inc., who encouraged innovation throughout his career. All royalties will be donated to the San Diego Foundation/Dr. Sadanand Singh Fund.
Publisher: Plural Publishing
ISBN: 9781597564458
Category : Audiology
Languages : en
Pages : 0
Book Description
Translational research has been present and ongoing for decades and yet, in spite of The National Institutes of Health promoting this "bench-to-bedside" approach since 2006, its adoption by the professions of speech-language pathology and audiology has been relatively scant and mostly individually approached. Although efforts have been made in this direction by individuals, the communication sciences and disorders professions are somewhat behind the curve in not addressing this issue directly.. For practicing clinicians, researchers, and students taking research seminars, Translational Speech-Language Pathology and Audiology examines the broad fields of laboratory, clinical, and public health research. Interdisciplinary and cross-disciplinary in scope, it aims to expedite the translation of related discoveries into new and improved standards of care. This series of short essays also honors Dr. Sadanand Singh, the late CEO and Founder of Plural Publishing, Inc., who encouraged innovation throughout his career. All royalties will be donated to the San Diego Foundation/Dr. Sadanand Singh Fund.