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Author: Graziano Pinna
Publisher: Springer Nature
ISBN: 1071632183
Category : Medical
Languages : en
Pages : 360
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Book Description
This volume explores the latest experimental techniques in animal models of PTSD and humans affected by PTSD. The methods discussed in this book cover topics such as translational research; addressing sex differences; highlighting the state-of-the-art of biomarker discovery in the development and maintenance of PTSD; and looks at new promising agents to enhance fear extinction retention that may help millions of individuals that suffer from this debilitating disorder worldwide. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Translational Methods for PTSD Research is a valuable resource that will help researchers understand and learn more about this important disorder.
Author: Graziano Pinna
Publisher: Springer Nature
ISBN: 1071632183
Category : Medical
Languages : en
Pages : 360
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Book Description
This volume explores the latest experimental techniques in animal models of PTSD and humans affected by PTSD. The methods discussed in this book cover topics such as translational research; addressing sex differences; highlighting the state-of-the-art of biomarker discovery in the development and maintenance of PTSD; and looks at new promising agents to enhance fear extinction retention that may help millions of individuals that suffer from this debilitating disorder worldwide. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Translational Methods for PTSD Research is a valuable resource that will help researchers understand and learn more about this important disorder.
Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388
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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309109264
Category : Medical
Languages : en
Pages : 224
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Book Description
Mental disorders, including posttraumatic stress disorder (PTSD), constitute an important health care need of veterans, especially those recently separated from service. Treatment of Posttraumatic Stress Disorder: An Assessment of the Evidence takes a systematic look the efficacy of pharmacologic and psychological treatment modalities for PTSD on behalf of the Department of Veterans Affairs. By reviewing existing studies in order to draw conclusions about the strength of evidence on several types of treatment, the Committee on the Treatment of Posttraumatic Stress Disorder found that many of these studies were faulty in design and performance, and that relatively few of these studies have been conducted in populations of veterans, despite suggestions that civilian and veteran populations respond differently to various types of treatment. The committee also notes that the evidence is scarce on the acceptability, efficacy, or generalizability of treatment in ethnic and cultural minorities, as few studies stratified results by ethnic background. Despite challenges in the consistency, quality, and depth of research, the committee found the evidence sufficient to conclude the efficacy of exposure therapies in treating PTSD. The committee found the evidence inadequate to determine efficacy of different types of pharmacotherapies, of three different psychotherapy modalities, and of psychotherapy delivered in group formats. The committee also made eight critical recommendations, some in response to the VA's questions related to recovery and the length and timing of PTSD treatment, and others addressing research methodology, gaps in evidence and funding issues.
Author: Blessen C. Eapen
Publisher: Elsevier Health Sciences
ISBN: 0323779441
Category : Medical
Languages : en
Pages : 594
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Book Description
The only review book currently available in this complex field, Brain Injury Medicine: Board Review focuses on the prevention, diagnosis, treatment, and management of individuals with varying severity levels of brain injury. Focused, high-yield content prepares you for success on exams and in practice, with up-to-date coverage of traumatic brain injury (TBI), stroke, CNS neoplasms, anoxic brain injury, and other brain disorders. This unique review tool is ideal for residents, fellows, and practitioners studying or working in the field and preparing to take the brain injury medicine exam. Supports self-assessment and review with 200 board-style questions and explanations. Covers the information you need to know on traumatic brain injury by severity and pattern, neurologic disorders, systemic manifestations, rehabilitation problems and outcomes, and basic science. Includes questions on patient management including patient evaluation and diagnosis, prognosis/risk factors, and applied science. Discusses key topics such as neurodegeneration and dementia; proteomic, genetic, and epigenetic biomarkers in TBI; neuromodulation and neuroprosthetics; and assistive technology. Reviews must-know procedures including acute emergency management and critical care; post-concussion syndrome assessment, management and treatment; diagnostic procedures and electrophysiology; neuroimaging, and brain death criteria. Ensures efficient, effective review with content written by experts in physical medicine and rehabilitation, neurology, and psychiatry and a format that mirrors the board exam outline.
Author: George G. Nomikos
Publisher: Academic Press
ISBN: 0128031646
Category : Medical
Languages : en
Pages : 460
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Book Description
Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. - Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development - Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders - Includes chapters written by international experts from industry and academia
Author: Matthew Tull
Publisher: Academic Press
ISBN: 0128162899
Category : Psychology
Languages : en
Pages : 654
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Book Description
Emotion in Posttraumatic Stress Disorder provides an up-to-date review of the empirical research on the relevance of emotions, such as fear, anxiety, shame, guilt, and disgust to posttraumatic stress disorder (PTSD). It also covers emerging research on the psychophysiology and neurobiological underpinnings of emotion in PTSD, as well as the role of emotion in the behavioral, cognitive, and affective difficulties experienced by individuals with PTSD. It concludes with a review of evidence-based treatment approaches for PTSD and their ability to mitigate emotion dysfunction in PTSD, including prolonged exposure, cognitive processing therapy, and acceptance-based behavioral therapy. - Identifies how emotions are central to understanding PTSD. - Explore the neurobiology of emotion in PTSD. - Discusses emotion-related difficulties in relation to PTSD, such as impulsivity and emotion dysregulation. - Provides a review of evidence-based PTSD treatments that focus on emotion.
Author: Abram Kardiner
Publisher: Martino Fine Books
ISBN: 9781614273332
Category : Psychology
Languages : en
Pages : 270
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Book Description
2012 Reprint of 1941 Edition. Exact facsimile of the original edition, not reproduced with Optical Recognition Software. Most PTSD authors agree that Abram Kardiner's "Traumatic Neuroses of War" is the seminal psychological work on PTSD. In this work Kardiner distilled much psychiatric thought on the traumatic syndrome resulting from World War II, with what he had termed "neurosis of war." The symptoms of this syndrome included features such as fixation on the trauma, constriction of personality functioning and atypical dream life. Kardiner provided powerful new insights in these classic texts on the phenomenology, nosology, and treatment of war-related stress, thereby anticipating virtually every aspect of contemporary research on PTSD. Although Kardiner had observed war neuroses since 1925, when he was attending specialist at the U.S. Veterans Hospital, he was only able to theorize them to his satisfaction after he had written "The Individual and His Society," which dealt with the problems of adaptation. He came to see that in the traumatic neurosis of the war the defensive maneuver to ward off the trauma sometimes destroyed the individual's adaptive capacity. Thus, the traumatic neurosis of war was the result of an adaptive failure, not a conflictual illness. So concluding, Kardiner re-introduced the concept of traumatic neurosis into psychoanalytic theory.
Author: Adebobola Imeh-Nathaniel
Publisher: Frontiers Media SA
ISBN: 2832523625
Category : Science
Languages : en
Pages : 155
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Book Description
Author: Linda Chapman
Publisher: W. W. Norton & Company
ISBN: 0393707881
Category : Medical
Languages : en
Pages : 268
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Book Description
Nonverbal interactions are applied to trauma treatment for more effective results. The model of treatment developed here is grounded in the physical, psychological, and cognitive reactions children have to traumatic experiences and the consequences of those experiences. The approach to treatment utilizes the integrative capacity of the brain to create a self, foster insight, and produce change. Treatment strategies are based on cutting-edge understanding of neurobiology, the development of the brain, and the storage and retrieval of traumatic memory. Case vignettes illustrate specific examples of the reactions of children, families, and teens to acute and repeated exposure to traumatic events. Also presented is the most recent knowledge of the role of the right hemisphere (RH) in development and therapy. Right brain communication, and how to recognize the non-verbal symbolic and unconscious, affective processes will be explained, along with examples of how the therapist can utilize art making, media, tools, and self to engage in a two-person biology.
Author: Terri L. Tanielian
Publisher: Rand Corporation
ISBN: 0833044540
Category : Business & Economics
Languages : en
Pages : 499
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Book Description
Since October 2001, approximately 1.64 million U.S. troops have been deployed for Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) in Afghanistan and Iraq. Early evidence suggests that the psychological toll of these deployments -- many involving prolonged exposure to combat-related stress over multiple rotations -- may be disproportionately high compared with the physical injuries of combat. In the face of mounting public concern over post-deployment health care issues confronting OEF/OIF veterans, several task forces, independent review groups, and a Presidential Commission have been convened to examine the care of the war wounded and make recommendations. Concerns have been most recently centered on two combat-related injuries in particular: post-traumatic stress disorder and traumatic brain injury. With the increasing incidence of suicide and suicide attempts among returning veterans, concern about depression is also on the rise. The study discussed in this monograph focuses on post-traumatic stress disorder, major depression, and traumatic brain injury, not only because of current high-level policy interest but also because, unlike the physical wounds of war, these conditions are often invisible to the eye, remaining invisible to other servicemembers, family members, and society in general. All three conditions affect mood, thoughts, and behavior; yet these wounds often go unrecognized and unacknowledged. The effect of traumatic brain injury is still poorly understood, leaving a large gap in knowledge related to how extensive the problem is or how to address it. RAND conducted a comprehensive study of the post-deployment health-related needs associated with these three conditions among OEF/OIF veterans, the health care system in place to meet those needs, gaps in the care system, and the costs associated with these conditions and with providing quality health care to all those in need. This monograph presents the results of our study, which should be of interest to mental health treatment providers; health policymakers, particularly those charged with caring for our nation's veterans; and U.S. service men and women, their families, and the concerned public. All the research products from this study are available at http://veterans.rand.org. Data collection for this study began in April 2007and concluded in January 2008. Specific activities included a critical reviewof the extant literature on the prevalence of post-traumatic stress disorder, major depression, and traumatic brain injury and their short- and long-term consequences; a population-based survey of service members and veterans who served in Afghanistan or Iraq to assess health status and symptoms, as well asutilization of and barriers to care; a review of existing programs to treat service members and veterans with the three conditions; focus groups withmilitary service members and their spouses; and the development of a microsimulation model to forecast the economic costs of these conditions overtime. Among our recommendations is that effective treatments documented in the scientific literature -- evidence-based care -- are available for PTSD and major depression. Delivery of such care to all veterans with PTSD or majordepression would pay for itself within two years, or even save money, by improving productivity and reducing medical and mortality costs. Such care may also be a cost-effective way to retain a ready and healthy military force for the future. However, to ensure that this care is delivered requires system-level changes across the Department of Defense, the Department of Veterans Affairs, and the U.S. health care system.
