Author: Claus Lindner
Publisher:
ISBN:
Category :
Languages : en
Pages : 311
Get Book Here
Book Description
Several clinical studies for non-invasive estimation of tissue hemodynamics by the combination of two diffuse optical techniques, time-resolved and diffuse correlation spectroscopy, were carried out in collaboration with local hospitals. These led to the 1rst application of hybrid diffuse optics in the characterization of healthy and pathological human thyroid tissue and the initiation of a European Horizon 2020 research project aiming at signi1cantly improving the current thyroid cancer screening process. The advantages of the hybrid diffuse optical device allowed to gain information on cerebral oxygen metabolism and improved estimation of cerebral blood 2ow. Data was collected from patients without brain diseases as well as healthy volunteers in clinical and surgical environments. The diffuse optical measurements were shown to correlate with the bispectral index, a widely used anesthesia monitor in the clinic. The optically derived parameters demonstrated the conservation of physiological coupling between cerebral blood 2ow and oxygen metabolism in patients under propofol-induced anesthesia. Additional studies focused on the investigation of microvascular cerebral physiology in response to common challenges in surgical procedures. These were simulated on healthy subjects and studied in depth. Overall, this work pushes the limits of the clinical translation of hybrid diffuse optics paving the way for new applications.
Author: S.R. Benbadis
Publisher: Springer Science & Business Media
ISBN: 1848821271
Category : Medical
Languages : en
Pages : 1966
Get Book Here
Book Description
Atlas of Epilepsies is a landmark, all-encompassing, illustrated reference work and hands-on guide to the diagnosis, management and treatment of epilepsy in all its forms and across all age groups. The premier text in the field with over one thousand images, the Atlas’s highly illustrative approach tackles the difficult subject of epileptic seizures and epileptic syndromes, accompanied by sequential photographs of each management step. Intraoperative photographs are accompanied by detailed figure legends describing nuances, subtleties, and the thought processes involved in each step, providing a fuller understanding of each procedure. The Atlas draws on the expertise of over 300 internationally-renowned experts, and is liberally interspersed with clinical insights and personal vignettes that offer helpful tips, technical advice and critical knowledge to the clinician and scholar. The thorough and complete table of contents includes dedicated sections or chapters on important topics such as neonatal and pediatric seizures; imitators of epilepsy; EEG and neuroimaging; psychiatric and quality of life aspects of epilepsy; and a complete guide to treatment options including current and up-to-date chapters on pharmaceuticals, surgical procedures, and additional and alternative treatments. No other publication addresses epilepsies as thoroughly and completely as the Atlas of Epilepsies. Exhaustive and illustrative, convenient and current, this reference is sure to be the premier text on epilepsy for many years to come.
Author: Irving J. Bigio
Publisher: Cambridge University Press
ISBN: 0521876567
Category : Medical
Languages : en
Pages : 703
Get Book Here
Book Description
Based on physical science principles, Quantitative Biomedical Optics covers theory, instrumentation, methods and applications, with practical exercises and problem sets.
Author: Mithun Kuniyil Ajith Singh
Publisher: Springer Nature
ISBN: 9811539847
Category : Science
Languages : en
Pages : 393
Get Book Here
Book Description
This book highlights the use of LEDs in biomedical photoacoustic imaging. In chapters written by key opinion leaders in the field, it covers a broad range of topics, including fundamentals, principles, instrumentation, image reconstruction and data/image processing methods, preclinical and clinical applications of LED-based photoacoustic imaging. Apart from preclinical imaging studies and early clinical pilot studies using LED-based photoacoustics, the book includes a chapter exploring the opportunities and challenges of clinical translation from an industry perspective. Given its scope, the book will appeal to scientists and engineers in academia and industry, as well as medical experts interested in the clinical applications of photoacoustic imaging.
Author: Martin Smith
Publisher: Oxford University Press
ISBN: 0198739559
Category : Medical
Languages : en
Pages : 457
Get Book Here
Book Description
The Oxford Textbook of Neurocritical Care provides an authoritative and up-to-date summary of the scientific basis, clinical techniques and management guidelines in this exciting clinical discipline. Authored by an international team of expert practitioners this textbook reflects world-wide practice.
Author: David A. Boas
Publisher: CRC Press
ISBN: 1420090372
Category : Medical
Languages : en
Pages : 816
Get Book Here
Book Description
Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental
Author: Arno Villringer
Publisher: Boom Koninklijke Uitgevers
ISBN: 9780306455858
Category : Science
Languages : en
Pages : 274
Get Book Here
Book Description
Covers the latest developments in optical imaging of the brain.
Author: Panicos A. Kyriacou
Publisher: Academic Press
ISBN: 012823525X
Category : Technology & Engineering
Languages : en
Pages : 508
Get Book Here
Book Description
Photoplethysmography: Technology, Signal Analysis, and Applications is the first comprehensive volume on the theory, principles, and technology (sensors and electronics) of photoplethysmography (PPG). It provides a detailed description of the current state-of-the-art technologies/optical components enabling the extreme miniaturization of such sensors, as well as comprehensive coverage of PPG signal analysis techniques including machine learning and artificial intelligence. The book also outlines the huge range of PPG applications in healthcare, with a strong focus on the contribution of PPG in wearable sensors and PPG for cardiovascular assessment. - Presents the underlying principles and technology surrounding PPG - Includes applications for healthcare and wellbeing - Focuses on PPG in wearable sensors and devices - Presents advanced signal analysis techniques - Includes cutting-edge research, applications and future directions
Author: Carolyn A. Staton
Publisher: John Wiley & Sons
ISBN: 047002934X
Category : Medical
Languages : en
Pages : 410
Get Book Here
Book Description
Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Author: Michael Brainin
Publisher: Cambridge University Press
ISBN: 1107047498
Category : Medical
Languages : en
Pages : 425
Get Book Here
Book Description
Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
