Total Synthesis and SAR of Thapsigargin and Related Analogues and Mechanistic Studies of Perovskite-mediated Suzuki Reactions

Total Synthesis and SAR of Thapsigargin and Related Analogues and Mechanistic Studies of Perovskite-mediated Suzuki Reactions PDF Author: S. P. Andrews
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 676

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I. Mechanistic and Synthetic Investigations of Group VI and Group VIII Transition Metal-mediated Cyclization Reactions

I. Mechanistic and Synthetic Investigations of Group VI and Group VIII Transition Metal-mediated Cyclization Reactions PDF Author: Joseph Anthony Suriano
Publisher:
ISBN:
Category :
Languages : en
Pages : 476

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From Natural Polyphenols to Synthetic Bioactive Analogues

From Natural Polyphenols to Synthetic Bioactive Analogues PDF Author: Corrado Tringali
Publisher: MDPI
ISBN: 3039367048
Category : Technology & Engineering
Languages : en
Pages : 98

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Book Description
This Special Issue is focused on natural polyphenols and their synthetic bioactive analogues. It is composed of one review on aza- and azo-stilbenes as bioisosteric analogs of the stilbenoid resveratrol and four original articles, including studies on synthetic (bisphenol neolignans inspired by honokiol, multicomponent synthesis of polyphenols), and natural polyphenols (polyphenols from Tamarix ramosissima and Melanoleuca styphelioides) as antiproliferative, anti-Alzheimer’s, antioxidant, antimicrobial, or anti-inflammatory agents.

Electrospun Nanofibers

Electrospun Nanofibers PDF Author: Mehdi Afshari
Publisher: Woodhead Publishing
ISBN: 0081009119
Category : Technology & Engineering
Languages : en
Pages : 650

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Book Description
Electrospun Nanofibers covers advances in the electrospinning process including characterization, testing and modeling of electrospun nanofibers, and electrospinning for particular fiber types and applications. Electrospun Nanofibers offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science. Electrospinning is the most commercially successful process for the production of nanofibers and rising demand is driving research and development in this field. Rapid progress is being made both in terms of the electrospinning process and in the production of nanofibers with superior chemical and physical properties. Electrospinning is becoming more efficient and more specialized in order to produce particular fiber types such as bicomponent and composite fibers, patterned and 3D nanofibers, carbon nanofibers and nanotubes, and nanofibers derived from chitosan. - Provides systematic and comprehensive coverage of the manufacture, properties, and applications of nanofibers - Covers recent developments in nanofibers materials including electrospinning of bicomponent, chitosan, carbon, and conductive fibers - Brings together expertise from academia and industry to provide comprehensive, up-to-date information on nanofiber research and development - Offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science

Antitumor and Anti-HIV Agents from Natural Products

Antitumor and Anti-HIV Agents from Natural Products PDF Author: Kyoko Nakagawa-Goto
Publisher:
ISBN: 9783039430086
Category :
Languages : en
Pages : 338

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Book Description
Cancer is the second leading cause of death worldwide, and was accountable for an estimated 9.6 million deaths in 2018. Nowadays, about 1 in 6 deaths in the world is due to cancer. Another major global public health issue is HIV. Over 70 million people have been infected with the HIV virus and about 35 million people have died of HIV-related illness, since the start of the epidemic. We have been fighting against these two serious diseases by finding successful treatments. The discovery of effective drugs is important for fighting cancer and HIV. Natural products, which are secondary metabolites produced by various living organisms, have been playing a principal role in drug discovery and developments, because of their structural and biological diversity. Many clinically used drugs have come from natural products; for example, more than 60% of anticancer drugs currently in clinical use are derived from natural sources. This Special Issue aims to collect original research and review articles focusing on notable and recent contributions to the discovery and development of novel anticancer and anti-HIV drug candidates from natural sources. Up-to-date knowledge from various research fields is welcome. This could be of great interest for scientists working in different research areas, such as natural product chemistry, including isolation and structural elucidation; phytochemistry; medicinal chemistry, including chemically modified natural compounds with improved biological activity; pharmacology; molecular biology; mechanisms of action study using natural products or related compounds; pharmacognosy, etc. Biological studies of natural extracts without an appropriate chemical characterization may not be considered.

Flavonoids and Their Disease Prevention and Treatment Potential

Flavonoids and Their Disease Prevention and Treatment Potential PDF Author: H.P. Vasantha Rupasinghe
Publisher: MDPI
ISBN: 3036500006
Category : Science
Languages : en
Pages : 346

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Book Description
Flavonoids are ubiquitously present in plant-based foods and natural health products. The molecule of flavonoids is characterized by a 15-carbon skeleton of C6–C3–C6, with the different structural configuration of subclasses. The major subclasses of flavonoids with health-promotional properties are the flavanols or catechins (e.g., epigallocatechin 3-gallate from green tea), the flavones (e.g., apigenin from celery), the flavonols (e.g., quercetin glycosides from apples, berries, and onion), the flavanones (e.g., naringenin from citrus), the anthocyanins (e.g., cyanidin-3-O-glucoside from berries), and the isoflavones (e.g., genistein from soya beans). Scientific evidence has strongly shown that regular intake of dietary flavonoids in efficacious amounts reduces the risk of oxidative stress- and chronic inflammation-mediated pathogenesis of human diseases such as cardiovascular disease, certain cancers, and neurological disorders. The physiological benefits of dietary flavonoids have been demonstrated to be due to multiple mechanisms of action, including regulating redox homeostasis, epigenetic regulations, activation of survival genes and signaling pathways, regulation of mitochondrial function and bioenergetics, and modulation of inflammation response. The role of flavonoids on gut microbiota and the impact of microbial metabolites of flavonoids on optimal health has begun to unravel. The complex physiological modulations of flavonoid molecules are due to their structural diversity. However, some flavonoids are not absorbed well, and their bioavailability could be enhanced through structural modifications and applications of nanotechnology, such as encapsulation. This Special Issue consists of four review articles on flavonoids and 15 original research articles, which cover the latest findings on the role of dietary flavonoids and their derivatives in disease prevention and treatment.

Brain Mechanisms of Sleep

Brain Mechanisms of Sleep PDF Author: Dennis J. McGinty
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 464

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Optics for AI and AI for Optics

Optics for AI and AI for Optics PDF Author: Jinlong Wei
Publisher: MDPI
ISBN: 3039363980
Category : Technology & Engineering
Languages : en
Pages : 162

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Book Description
Artificial intelligence is deeply involved in our daily lives via reinforcing the digital transformation of modern economies and infrastructure. It relies on powerful computing clusters, which face bottlenecks of power consumption for both data transmission and intensive computing. Meanwhile, optics (especially optical communications, which underpin today’s telecommunications) is penetrating short-reach connections down to the chip level, thus meeting with AI technology and creating numerous opportunities. This book is about the marriage of optics and AI and how each part can benefit from the other. Optics facilitates on-chip neural networks based on fast optical computing and energy-efficient interconnects and communications. On the other hand, AI enables efficient tools to address the challenges of today’s optical communication networks, which behave in an increasingly complex manner. The book collects contributions from pioneering researchers from both academy and industry to discuss the challenges and solutions in each of the respective fields.

Electrochemical Impedance Spectroscopy

Electrochemical Impedance Spectroscopy PDF Author: Marwa El-Azazy
Publisher: BoD – Books on Demand
ISBN: 1789852153
Category : Science
Languages : en
Pages : 169

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Book Description
Electrochemical Impedance Spectroscopy is a compendium of contributions from experts in the field of electrochemical impedance spectroscopy (EIS). This compilation of investigations and reviews addresses the groundbreaking applications of EIS in different fields. An array of exploitations are revealed throughout this book such as the use of EIS in monitoring and controlling of corrosion, in medicine where accurate information on fluid distribution is needed as well as environmental applications in food, water, and drug analyses. Competency of EIS as an approach compared to the traditional electrochemical techniques is assessed in almost every application. This book, therefore, is a valuable reference for students, researchers, and anyone interested in electrochemical impedance spectroscopy.