Total Syntheses of (+)-Zampanolide and (+)-Dactylolide

Total Syntheses of (+)-Zampanolide and (+)-Dactylolide PDF Author: Igor Safonov
Publisher:
ISBN:
Category :
Languages : en
Pages : 366

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Total Syntheses of (+)-Zampanolide and (+)-Dactylolide

Total Syntheses of (+)-Zampanolide and (+)-Dactylolide PDF Author: Igor Safonov
Publisher:
ISBN:
Category :
Languages : en
Pages : 366

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A Total Synthesis of (-)-zampanolide and (-)-dactylolide

A Total Synthesis of (-)-zampanolide and (-)-dactylolide PDF Author: Min Hu
Publisher:
ISBN:
Category :
Languages : en
Pages : 384

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Total Synthesis and Biological Evaluation of (-)-zampanolide, (-)-dactylolide and of Analogs Thereof

Total Synthesis and Biological Evaluation of (-)-zampanolide, (-)-dactylolide and of Analogs Thereof PDF Author: Didier Zurwerra
Publisher:
ISBN:
Category :
Languages : en
Pages :

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The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A

The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A PDF Author: Jeffrey L. Henry
Publisher:
ISBN:
Category :
Languages : en
Pages : 338

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Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis PDF Author: Michael Harmata
Publisher: Academic Press
ISBN: 0123865409
Category : Chemistry, Organic
Languages : en
Pages : 456

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Book Description
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field.

Chemical Biology of Natural Products

Chemical Biology of Natural Products PDF Author: David J. Newman
Publisher: CRC Press
ISBN: 1351643282
Category : Medical
Languages : en
Pages : 650

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Book Description
Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

The Total Synthesis of the Cytotoxic Marine Macrolide (-)-dactylolide

The Total Synthesis of the Cytotoxic Marine Macrolide (-)-dactylolide PDF Author: Ignace Louis
Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 284

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Stereoselective Syntheses of Tetrahydropyrans

Stereoselective Syntheses of Tetrahydropyrans PDF Author: Kiyoun Lee
Publisher: Springer
ISBN: 3319044621
Category : Science
Languages : en
Pages : 198

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Book Description
In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and (±)diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology.

The Large Scale Synthesis of the C19 to C32 Portion of Swinholide A, the Total Synthesis of Dactylolide, and the Synthesis of a Novel Bryostatin Analogue

The Large Scale Synthesis of the C19 to C32 Portion of Swinholide A, the Total Synthesis of Dactylolide, and the Synthesis of a Novel Bryostatin Analogue PDF Author: Carina Cristina Sanchez
Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 544

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Applied Cross-Coupling Reactions

Applied Cross-Coupling Reactions PDF Author: Yasushi Nishihara
Publisher: Springer Science & Business Media
ISBN: 3642323685
Category : Science
Languages : en
Pages : 247

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Book Description
“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.