Total Knockout

Total Knockout PDF Author: Taylor Morris
Publisher: Simon and Schuster
ISBN: 1442459298
Category : Juvenile Fiction
Languages : en
Pages : 276

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Book Description
There's nothing ordinary about Lucia Latham - she gets straight A's, she's been middle school Class President for two years running and she's a great boxer - nothing is more fun than a good old sparring match with best friend Cooper, especially since she usually wins. In short, there are few things Lucia tackles that don't turn out exactly how she wants them. So at the beginning of her 8th grade year, Lucia has no reason to believe that things won't continue being easy - until she sticks her foot in her mouth in a HUGE way. Then it seems her carefully constructed world is crashing down around her. Can she regain her super star status or will she be forced to lower her expectations?

Total Knockout

Total Knockout PDF Author: Taylor Morris
Publisher: Simon and Schuster
ISBN: 1442459298
Category : Juvenile Fiction
Languages : en
Pages : 276

Get Book Here

Book Description
There's nothing ordinary about Lucia Latham - she gets straight A's, she's been middle school Class President for two years running and she's a great boxer - nothing is more fun than a good old sparring match with best friend Cooper, especially since she usually wins. In short, there are few things Lucia tackles that don't turn out exactly how she wants them. So at the beginning of her 8th grade year, Lucia has no reason to believe that things won't continue being easy - until she sticks her foot in her mouth in a HUGE way. Then it seems her carefully constructed world is crashing down around her. Can she regain her super star status or will she be forced to lower her expectations?

The Handbook of Medicinal Chemistry

The Handbook of Medicinal Chemistry PDF Author: Andrew Davis
Publisher: Royal Society of Chemistry
ISBN: 1782621830
Category : Science
Languages : en
Pages : 789

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Book Description
Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.

Knock-out Blackjack

Knock-out Blackjack PDF Author: Olaf Vancura
Publisher: Huntington Press Inc
ISBN: 0929712315
Category : Games & Activities
Languages : en
Pages : 190

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Book Description
Revolutionary card-counting system for blackjack. All you need to know is how to add and subtract by one. This expanded Second Edition is easier to understand, learn, and use.

The Guide to Investigation of Mouse Pregnancy

The Guide to Investigation of Mouse Pregnancy PDF Author: B. Anne Croy
Publisher: Academic Press
ISBN: 0123947944
Category : Science
Languages : en
Pages : 829

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Book Description
The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. - Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications - Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes - Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation - Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success

T.k.o.

T.k.o. PDF Author: Ana Layne
Publisher:
ISBN: 9781500236366
Category : Fiction
Languages : en
Pages : 280

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Book Description
**Mature Content Warning** Recommended for ages 17+ due to language and sexual content.Samantha Montgomery's life changed in an instant...One minute you think you know someone, and the next minute, they're a stranger. When Sam was forced to make a decision, she ended up alone. All. Alone. One step inside a gym was all it took. The ring became her escape. She was more determined than ever to move on and forget her old life. That was, until she saw those blue eyes.Cole Johnson wants nothing more than to spend his time training and dominating in the ring.It's what he's good at. It's what he does. He has no time, or desire, to be entangled in a relationship. But after one look at Sam, his whole world shifted. He needs her, he needs to know her, only its not so easy. This may be a fight he can't win. Will he be able to win Sam over? Or will it end in a total knock out?

Fatty Acid and Lipotoxicity in Obesity and Diabetes

Fatty Acid and Lipotoxicity in Obesity and Diabetes PDF Author: Gregory R. Bock
Publisher: John Wiley & Sons
ISBN: 9780470985564
Category : Medical
Languages : en
Pages : 222

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Book Description
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and β cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.

Nutrition and Growth

Nutrition and Growth PDF Author: B. Koletzko
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318057061
Category : Medical
Languages : en
Pages : 163

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Book Description
It is a well-known fact that children's growth depends on the quality of their nutrition. However, the mechanisms of fetal and child growth and their interactions with nutrition have not yet been fully elucidated and still pose a challenge to those engaged in the field. Exchanging concepts and knowledge among professionals of various disciplines thus remains very important. This second 'Yearbook' provides an update on the research published between 2013 and 2015. An international team of experts presents papers that shed light on the mechanisms of interaction between nutrition and growth, and provide insight to the readers. Each paper is briefly summarized and supplemented with editorial comments which evaluate the clinical importance of each article and discuss its application.This 'Yearbook' is an important tool for practicing physicians, including pediatricians, subspecialists in pediatric gastroenterology, metabolism and nutrition, and endocrinology. Nutritionists and dieticians, as well as other health professionals involved in the care of children, will also find this to be a useful resource.

The Laboratory Mouse

The Laboratory Mouse PDF Author: Hans Hedrich
Publisher: Academic Press
ISBN: 012382009X
Category : Science
Languages : en
Pages : 869

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Book Description
The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. - Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research - Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology - Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Vitamin D

Vitamin D PDF Author: Martin Hewison
Publisher: Academic Press
ISBN: 0128099666
Category : Science
Languages : en
Pages : 1182

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Book Description
Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease. - Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D - Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles - Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis, human physiology, diagnosis and management, nutrition, sunlight, genetics and vitamin D deficiency - Volume II of this collection presents a clinical focus on disorders, analogs, cancer; immunity, inflammation and disease and therapeutic applications

The Complete Delta Force Shooters

The Complete Delta Force Shooters PDF Author: M. L. Buchman
Publisher: Buchman Bookworks, Inc.
ISBN:
Category : Fiction
Languages : en
Pages : 182

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Book Description
(Five romance short story collection with exclusive author intros.) Praise for M. L.’s Delta Force series: * “The contemporary standard bearer of military romance.” * “Top 10 Romance of the Year.” * “(For) a romantic adrenaline junkie.” Discover tales of danger, adventure, and ever-lasting love with the top warriors anywhere. Don’t miss the companion collection: The Complete Delta Force Warriors. (previously published as individual stories)