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Author: Michael R. Buchanan
Publisher: CRC Press
ISBN: 9780849376498
Category : Medical
Languages : en
Pages : 238
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Book Description
This new multi-authored book reviews the current understanding of the role of thrombin in venous and arterial thrombosis and its inhibition in the clinical setting. Heparin, the most widely used antithrombotic, does not effectively regulate thrombin or its formation. Accumulating evidence suggests that other antithrombins are effective in some of the situations where heparin is not. Discussions include the current knowledge on antithrombotic prophylaxis and therapy, from the perspective of the role in thrombin in venous and arterial vascular disease, the limitations of the current anticoagulant therapies, and potential and limitations of newer antithrombins currently being tested in several experimental and clinical settings. Thrombin helps the clinician to better rationalize the use of specific antithrombins in the prevention and management of thrombotic disease and provides the basic scientist with a better understanding of the goals the clinician attempts to achieve with antithrombotic therapy.
Author: Michael R. Buchanan
Publisher: CRC Press
ISBN: 9780849376498
Category : Medical
Languages : en
Pages : 238
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Book Description
This new multi-authored book reviews the current understanding of the role of thrombin in venous and arterial thrombosis and its inhibition in the clinical setting. Heparin, the most widely used antithrombotic, does not effectively regulate thrombin or its formation. Accumulating evidence suggests that other antithrombins are effective in some of the situations where heparin is not. Discussions include the current knowledge on antithrombotic prophylaxis and therapy, from the perspective of the role in thrombin in venous and arterial vascular disease, the limitations of the current anticoagulant therapies, and potential and limitations of newer antithrombins currently being tested in several experimental and clinical settings. Thrombin helps the clinician to better rationalize the use of specific antithrombins in the prevention and management of thrombotic disease and provides the basic scientist with a better understanding of the goals the clinician attempts to achieve with antithrombotic therapy.
Author: Durgesh Nandini Chauhan
Publisher: CRC Press
ISBN: 1040165281
Category : Medical
Languages : en
Pages : 533
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Book Description
Novel Phytopharmaceutical for Management of Disorders covers recent advances surrounding phytopharmaceuticals and their potential uses in the management of several disorders as well as in cosmetic benefits. Sections cover the concepts of phytopharmaceuticals and current highlights in disease management. This book also emphasizes phytopharmaceutical drug delivery studies in vivo–in vitro study to various target organs like lungs, liver, and brain. This book provides key information for everyone interested in disease management, drug discovery, and delivery, including medicinal chemists, cosmetic experts, nutritionists, toxicologists, drug formulators, and health care professionals. Students, professors, and researchers working in pharmaceutical sciences and beyond will also find the book useful considering the future prospect of phytodrug delivery for better treatment of various diseases. We will also focus on patents filed, technology transfer, market potential, and regulatory aspects of herbal nanomedicines, if any. However, research in this area is still at the exploratory stage. But, in the market, there are no such books available that have summarized all the contents on the point of research aspects. This book will be a continuation of the first volume and readers and the target audience will get all the knowledge related to this topic. Aims and scope: To understand the basic information and application of phytoconstituents To understand the various phytoconstituents-based formulations for disease management Herbal drugs used for cosmetic application Phytodrug delivery systems and their applications To provide detailed knowledge about the technical aspects of the formulation part To update readers with the latest research progress in this emerging research area To provide the details about patents filed, technology transfer, market potential, and regulatory aspects for the same
Author: V.S. Blanchette
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318030260
Category : Medical
Languages : en
Pages : 360
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Book Description
This updated and extended edition of the SickKids Handbook takes the reader through the entire field of pediatric thrombosis and hemostasis. An introductory section concisely explains the complex pathophysiology of thrombosis and hemostasis. The chapters that follow include practical, evidence-based information on the diagnosis and management of inherited and acquired bleeding disorders and thrombotic events of the venous, arterial, cardiac and central nervous systems that affect children. Special features include practical clinical algorithms and appendices that cite normal laboratory reference ranges, as well as recommended dosages of blood products and major hemostatic agents. A stand-alone chapter is dedicated to developmental hemostasis and bleeding in the neonate. A chapter on antithrombotic therapy in children gives succinct information on the old and new anticoagulants, antiplatelet drugs and thrombolytic agents. Written and reviewed by international experts in the field, this handbook is intended for health care professionals involved in the assessment and care of children with inherited and acquired bleeding and clotting disorders, including general and specialist pediatricians (in particular intensivists, neonatologists, cardiologists/cardiac surgeons, rheumatologists and nephrologists), hematologists/oncologists (pediatric and adult), as well as medical trainees, nurses, nurse practitioners and pharmacists.
Author: Stephanie J. Brister
Publisher:
ISBN:
Category : Antithrombins
Languages : en
Pages : 211
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Book Description
Author: Roger L. Lundblad
Publisher:
ISBN: 9781032203300
Category : Medical
Languages : en
Pages : 0
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Book Description
Chemical Biology of Thrombin is a comprehensive review of thrombin as regulatory protease, perhaps one of the most important enzymes in hemostasis. It focuses on work from 1970's to the present time. Thrombin has some emerging therapeutic uses such the treatment of pseudoaneurysms and an important role in the extravascular space.
Author: Marshall A. Lichtman
Publisher: McGraw Hill Professional
ISBN: 1264269218
Category : Medical
Languages : en
Pages : 689
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Book Description
A full-color clinical reference covering both common and uncommon blood disorders—distilled from the world’s leading hematology text Williams Manual of Hematology, Tenth Edition provides a concise, easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, this portable guide has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. This updated edition reflects the latest research and includes more than 100 full-color clinical photographs. Concise but comprehensive, this complete guide includes sections on: Initial Clinical Evaluation Disorders of Red Cells Disorders of Granulocytes Disorders of Monocytes and Macrophages Principles of Therapy for Neoplastic Hematological Disorders The Clonal Myeloid Disorders The Polyclonal Lymphoid Diseases The Clonal Lymphoid and Plasma Cell Diseases Disorders of Platelet and Hemostasis Disorders of Coagulation Proteins Thrombosis and Antithrombotic Therapy Transfusion and Hemapheresis
Author: Eisei Noiri
Publisher: Springer Science & Business Media
ISBN: 4431544127
Category : Medical
Languages : en
Pages : 416
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Book Description
This pocket-sized manual serves as a concise and ideal reference work for therapeutic approaches using apheresis, Covering both basic theory and clinical details to facilitate improved treatment and patient outcomes, the text considers a variety of diseases, including myasthenia gravis, multiple sclerosis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, nephrotic syndrome, TTP/TMA, dilated cardiomyopathy, and many other conditions. The books also reviews the growing trend towards adopting this unique therapy for a wide range of health management issues such as morbid obesity and/or type 2 diabetes, and for lowering LDL-cholesterol (cholesterol apheresis) in patients unresponsive to medication or lifestyle modification.
Author: Akbar Dorgalaleh
Publisher: Springer Nature
ISBN: 3031431561
Category : Medical
Languages : en
Pages : 464
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Book Description
This significantly updated new edition describes in detail the clinical presentations, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Author: Akbar Dorgalaleh
Publisher: Springer
ISBN: 3319767232
Category : Medical
Languages : en
Pages : 397
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Book Description
This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Author:
Publisher:
ISBN:
Category : Thromboembolism
Languages : en
Pages : 358
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Book Description
