The Use of Multiple Imputation for Data Subject to Limits of Detection

The Use of Multiple Imputation for Data Subject to Limits of Detection PDF Author: Ofer Harel
Publisher:
ISBN:
Category : Mathematical statistics
Languages : en
Pages : 27

Get Book Here

Book Description

The Use of Multiple Imputation for Data Subject to Limits of Detection

The Use of Multiple Imputation for Data Subject to Limits of Detection PDF Author: Ofer Harel
Publisher:
ISBN:
Category : Mathematical statistics
Languages : en
Pages : 27

Get Book Here

Book Description


Multiple Imputation of Missing Data in Practice

Multiple Imputation of Missing Data in Practice PDF Author: Yulei He
Publisher: CRC Press
ISBN: 0429530978
Category : Mathematics
Languages : en
Pages : 419

Get Book Here

Book Description
Multiple Imputation of Missing Data in Practice: Basic Theory and Analysis Strategies provides a comprehensive introduction to the multiple imputation approach to missing data problems that are often encountered in data analysis. Over the past 40 years or so, multiple imputation has gone through rapid development in both theories and applications. It is nowadays the most versatile, popular, and effective missing-data strategy that is used by researchers and practitioners across different fields. There is a strong need to better understand and learn about multiple imputation in the research and practical community. Accessible to a broad audience, this book explains statistical concepts of missing data problems and the associated terminology. It focuses on how to address missing data problems using multiple imputation. It describes the basic theory behind multiple imputation and many commonly-used models and methods. These ideas are illustrated by examples from a wide variety of missing data problems. Real data from studies with different designs and features (e.g., cross-sectional data, longitudinal data, complex surveys, survival data, studies subject to measurement error, etc.) are used to demonstrate the methods. In order for readers not only to know how to use the methods, but understand why multiple imputation works and how to choose appropriate methods, simulation studies are used to assess the performance of the multiple imputation methods. Example datasets and sample programming code are either included in the book or available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book). Key Features Provides an overview of statistical concepts that are useful for better understanding missing data problems and multiple imputation analysis Provides a detailed discussion on multiple imputation models and methods targeted to different types of missing data problems (e.g., univariate and multivariate missing data problems, missing data in survival analysis, longitudinal data, complex surveys, etc.) Explores measurement error problems with multiple imputation Discusses analysis strategies for multiple imputation diagnostics Discusses data production issues when the goal of multiple imputation is to release datasets for public use, as done by organizations that process and manage large-scale surveys with nonresponse problems For some examples, illustrative datasets and sample programming code from popular statistical packages (e.g., SAS, R, WinBUGS) are included in the book. For others, they are available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book)

Multiple Imputation in the Presence of a Detection Limit, with Applications

Multiple Imputation in the Presence of a Detection Limit, with Applications PDF Author: Shawn Carl Liebenberg
Publisher:
ISBN:
Category :
Languages : en
Pages : 342

Get Book Here

Book Description


Multiple Imputation in Practice

Multiple Imputation in Practice PDF Author: Trivellore Raghunathan
Publisher: CRC Press
ISBN: 1498770177
Category : Mathematics
Languages : en
Pages : 250

Get Book Here

Book Description
Multiple Imputation in Practice: With Examples Using IVEware provides practical guidance on multiple imputation analysis, from simple to complex problems using real and simulated data sets. Data sets from cross-sectional, retrospective, prospective and longitudinal studies, randomized clinical trials, complex sample surveys are used to illustrate both simple, and complex analyses. Version 0.3 of IVEware, the software developed by the University of Michigan, is used to illustrate analyses. IVEware can multiply impute missing values, analyze multiply imputed data sets, incorporate complex sample design features, and be used for other statistical analyses framed as missing data problems. IVEware can be used under Windows, Linux, and Mac, and with software packages like SAS, SPSS, Stata, and R, or as a stand-alone tool. This book will be helpful to researchers looking for guidance on the use of multiple imputation to address missing data problems, along with examples of correct analysis techniques.

Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1252

Get Book Here

Book Description


Multiple Imputation Analysis for Observational Data

Multiple Imputation Analysis for Observational Data PDF Author: Yulei He
Publisher: CRC Press
ISBN: 9781498722063
Category :
Languages : en
Pages : 506

Get Book Here

Book Description
Multiple Imputation of Missing Data in Practice: Basic Theory and Analysis Strategies provides a comprehensive introduction to the multiple imputation approach to missing data problems that are often encountered in data analysis. Over the past 40 years or so, multiple imputation has gone through rapid development in both theories and applications. It is nowadays the most versatile, popular, and effective missing-data strategy that is used by researchers and practitioners across different fields. There is a strong need to better understand and learn about multiple imputation in the research and practical community. Accessible to a broad audience, this book explains statistical concepts of missing data problems and the associated terminology. It focuses on how to address missing data problems using multiple imputation. It describes the basic theory behind multiple imputation and many commonly-used models and methods. These ideas are illustrated by examples from a wide variety of missing data problems. Real data from studies with different designs and features (e.g., cross-sectional data, longitudinal data, complex surveys, survival data, studies subject to measurement error, etc.) are used to demonstrate the methods. In order for readers not only to know how to use the methods, but understand why multiple imputation works and how to choose appropriate methods, simulation studies are used to assess the performance of the multiple imputation methods. Example datasets and sample programming code are either included in the book or available at a github site (https: //github.com/he-zhang-hsu/multiple_imputation_book). Key Features Provides an overview of statistical concepts that are useful for better understanding missing data problems and multiple imputation analysis Provides a detailed discussion on multiple imputation models and methods targeted to different types of missing data problems (e.g., univariate and multivariate missing data problems, missing data in survival analysis, longitudinal data, complex surveys, etc.) Explores measurement error problems with multiple imputation Discusses analysis strategies for multiple imputation diagnostics Discusses data production issues when the goal of multiple imputation is to release datasets for public use, as done by organizations that process and manage large-scale surveys with nonresponse problems For some examples, illustrative datasets and sample programming code from popular statistical packages (e.g., SAS, R, WinBUGS) are included in the book. For others, they are available at a github site (https: //github.com/he-zhang-hsu/multiple_imputation_book)

Flexible Imputation of Missing Data, Second Edition

Flexible Imputation of Missing Data, Second Edition PDF Author: Stef van Buuren
Publisher: CRC Press
ISBN: 0429960352
Category : Mathematics
Languages : en
Pages : 444

Get Book Here

Book Description
Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.

Nondetects and Data Analysis

Nondetects and Data Analysis PDF Author: Dennis R. Helsel
Publisher: Wiley-Interscience
ISBN:
Category : Mathematics
Languages : en
Pages : 276

Get Book Here

Book Description
STATISTICS IN PRACTICE Statistical methods for interpreting and analyzing censored environmental data Nondetects And Data Analysis: Statistics for Censored Environmental Data provides solutions for environmental scientists and professionals who need to interpret and analyze data that fall below the laboratory detection limit. Adapting survival analysis methods that have been successfully used in medical and industrial research, the author demonstrates, for the first time, their practical applications for studies of trace chemicals in air, water, soils, and biota. Readers quickly become proficient in these methods through the use of real-world examples that are solved using MINITAB® Release 14, a popular statistical software package, as well as other commonly used software packages. Everything needed to master these innovative statistical methods is provided, including: Accompanying Web site featuring answers to book exercises and datasets, as well as MINITAB® macros to perform methods, which are not available in the commercial version Methods for data with multiple detection limits Solutions for research studies in which all data are below detection limits Techniques for constructing confidence, prediction, and tolerance intervals for data with nond-tects Methods for data with multiple detection limits Chapters are organized by objective, such as computing intervals, comparing groups, and correlations, which enables readers to more easily apply the text to their particular research and goals. Extensive references to the literature for more in-depth research are provided; however, the text itself avoids complex math and calculus making it accessible to anyone in the environmental sciences. Environmental scientists and professionals will find the hands-on guidance and practical examples invaluable.

Analysis of Biomarker Data

Analysis of Biomarker Data PDF Author: Stephen W. Looney
Publisher: John Wiley & Sons
ISBN: 1118552458
Category : Medical
Languages : en
Pages : 424

Get Book Here

Book Description
A “how to” guide for applying statistical methods to biomarker data analysis Presenting a solid foundation for the statistical methods that are used to analyze biomarker data, Analysis of Biomarker Data: A Practical Guide features preferred techniques for biomarker validation. The authors provide descriptions of select elementary statistical methods that are traditionally used to analyze biomarker data with a focus on the proper application of each method, including necessary assumptions, software recommendations, and proper interpretation of computer output. In addition, the book discusses frequently encountered challenges in analyzing biomarker data and how to deal with them, methods for the quality assessment of biomarkers, and biomarker study designs. Covering a broad range of statistical methods that have been used to analyze biomarker data in published research studies, Analysis of Biomarker Data: A Practical Guide also features: A greater emphasis on the application of methods as opposed to the underlying statistical and mathematical theory The use of SAS®, R, and other software throughout to illustrate the presented calculations for each example Numerous exercises based on real-world data as well as solutions to the problems to aid in reader comprehension The principles of good research study design and the methods for assessing the quality of a newly proposed biomarker A companion website that includes a software appendix with multiple types of software and complete data sets from the book’s examples Analysis of Biomarker Data: A Practical Guide is an ideal upper-undergraduate and graduate-level textbook for courses in the biological or environmental sciences. An excellent reference for statisticians who routinely analyze and interpret biomarker data, the book is also useful for researchers who wish to perform their own analyses of biomarker data, such as toxicologists, pharmacologists, epidemiologists, environmental and clinical laboratory scientists, and other professionals in the health and environmental sciences.

Quantitative Methods for HIV/AIDS Research

Quantitative Methods for HIV/AIDS Research PDF Author: Cliburn Chan
Publisher: CRC Press
ISBN: 1498734251
Category : Mathematics
Languages : en
Pages : 309

Get Book Here

Book Description
Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.