The Theoretical Foundation of Dendritic Function PDF Download
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Author: Wilfrid Rall
Publisher: MIT Press
ISBN: 9780262193566
Category : Medical
Languages : en
Pages : 484
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Book Description
This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists.
Author: Wilfrid Rall
Publisher: MIT Press
ISBN: 9780262193566
Category : Medical
Languages : en
Pages : 484
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Book Description
This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists.
Author: Wilfried Rall
Publisher:
ISBN: 9780262283373
Category : Dendrites
Languages : en
Pages : 468
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Book Description
This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. Wilfrid Rall was a pioneer in establishing the integrative functions of neuronal dendrites that have provided a foundation for neurobiology in general and computational neuroscience in particular. This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. It brings together Rall's work over more than forty years, including his first papers extending cable theory to complex dendritic trees, his ground-breaking paper introducing compartmental analysis to computational neuroscience, and his studies of synaptic integration in motoneurons, dendrodendritic interactions, plasticity of dendritic spines, and active dendritic properties. Today it is well known that the brain's synaptic information is processed mostly in the dendrites where many of the plastic changes underlying learning and memory take place. It is particularly timely to look again at the work of a major creator of the field, to appreciate where things started and where they have led, and to correct any misinterpretations of Rall's work. The editors' introduction highlights the major insights that were gained from Rall's studies as well as from those of his collaborators and followers. It asks the questions that Rall proposed during his scientific career and briefly summarizes the answers.
Author: Larry Squire
Publisher: Elsevier
ISBN: 0080521800
Category : Medical
Languages : en
Pages : 1447
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Book Description
With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates.The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities.Key Features* Logically organized into 7 sections, with uniform editing of the content for a "one-voice" feel throughout all 54 chapters* Includes numerous text boxes with concise, detailed descriptions of specific experiments, disorders, methodological approaches, and concepts* Well-illustrated with over 850 full color figures, also included on the accompanying CD-ROM
Author: Giorgio A. Ascoli
Publisher: Springer Science & Business Media
ISBN: 1592592759
Category : Medical
Languages : en
Pages : 466
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Book Description
In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
Author: Christof Koch
Publisher: MIT Press
ISBN: 9780262112314
Category : Computers
Languages : en
Pages : 700
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Book Description
Kinetic Models of Synaptic Transmission / Alain Destexhe, Zachary F. Mainen, Terrence J. Sejnowski / - Cable Theory for Dendritic Neurons / Wilfrid Rall, Hagai Agmon-Snir / - Compartmental Models of Complex Neurons / Idan Segev, Robert E. Burke / - Multiple Channels and Calcium Dynamics / Walter M. Yamada, Christof Koch, Paul R. Adams / - Modeling Active Dendritic Processes in Pyramidal Neurons / Zachary F. Mainen, Terrence J. Sejnowski / - Calcium Dynamics in Large Neuronal Models / Erik De Schutter, Paul Smolen / - Analysis of Neural Excitability and Oscillations / John Rinzel, Bard Ermentrout / - Design and Fabrication of Analog VLSI Neurons / Rodney Douglas, Misha Mahowald / - Principles of Spike Train Analysis / Fabrizio Gabbiani, Christof Koch / - Modeling Small Networks / Larry Abbott, Eve Marder / - Spatial and Temporal Processing in Central Auditory Networks / Shihab Shamma / - Simulating Large Networks of Neurons / Alexander D. Protopapas, Michael Vanier, James M. Bower / ...
Author: Zhengbing Hu
Publisher: Springer Nature
ISBN: 303080478X
Category : Technology & Engineering
Languages : en
Pages : 186
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Book Description
This book comprises high-quality refereed research papers presented at The Second International Symposium on Computer Science, Digital Economy and Intelligent Systems (CSDEIS2020), held in Moscow, Russia, on December 18–20, 2020, organized jointly by Moscow State Technical University and the International Research Association of Modern Education and Computer Science. The topics discussed in the book include state-of-the-art papers in computer science and their technological applications; intelligent systems and intellectual approaches; digital economics and methodological approaches. It is an excellent source of references for researchers, graduate students, engineers, management practitioners, and undergraduate students interested in computer science and their applications in engineering and management.
Author: Christof Koch
Publisher: Oxford University Press
ISBN: 0195181999
Category : Medical
Languages : en
Pages : 587
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Book Description
Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.
Author: John Robert Burger
Publisher: Springer Science & Business Media
ISBN: 1461464129
Category : Medical
Languages : en
Pages : 240
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Book Description
This book models an idealized neuron as being driven by basic electrical elements, the goal being to systematically characterize the logical properties of neural pulses. In order to constitute a system, neurons as pulsating devices may be represented using novel circuit elements as delineated in this book. A plausible brain system is implied by the delineated elements and logically follows from known and likely properties of a neuron. New to electrical science are novel pulse-related circuit elements involving recursive neurons. A recursive neuron, when properly excited, produces a self-sustaining pulse train that when sampled, provides a true output with a specified probability, and a false output with complementary probability. Because of its similarity to the qubits of quantum mechanics, the recursive pulsating neuron is termed a simulated qubit. Recursive neurons easily function as controlled toggle devices and so are capable of massively parallel calculations, this being a new dimension in brain functioning as described in this book. Simulated qubits and their possibilities are compared to the qubits of quantum physics. Included in the book are suggested neural circuits for associative memory search via a randomized process of cue selection, and neural circuits for priority calculations. These serve to select returns from long term memory, which in turn determines one's next conscious thought or action based on past memorized experiences. The book reports on proposals involving electron tunneling between synapses, and quantum computations within neurons. Although not a textbook, there are easy exercises at the ends of chapters, and in the appendix there are twelve simulation experiments concerning neurons.
Author: Walter Freeman
Publisher: Springer Science & Business Media
ISBN: 1447103718
Category : Medical
Languages : en
Pages : 395
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Book Description
Cortical evoked potentials are of interest primarily as tests of changing neuronal excitabilities accompanying normal brain function. The first three steps in the anal ysis of these complex waveforms are proper placement of electrodes for recording, the proper choice of electrical or sensory stimulus parameters, and the establish ment of behavioral control. The fourth is development of techniques for reliable measurement. Measurement consists of comparison of an unknown entity with a set of standard scales or dimensions having numerical attributes in preassigned degree. A physical object can be described by the dimensions of size, mass, density, etc. In addition there are dimensions such as location, velocity, weight, hardness, etc. Some of these dimensions can be complex (e. g. size depends on three or more subsidiary coordi nates), and some can be interdependent or nonorthogonal (e. g. specification of size and mass may determine density). In each dimension the unit is defined with refer ence to a standard physical entity, e. g. a unit of mass or length, and the result of measurement is expressed as an equivalence between the unknown and the sum of a specified number of units of that entity. The dimensions of a complex waveform are elementary waveforms from which that waveform can be built by simple addition. Any finite single-valued function of time is admissible. They are called basis functions (lO, 15), and they can be expressed in numeric as well as geometric form.
Author: Bahman Zohuri
Publisher: Academic Press
ISBN: 0323957900
Category : Medical
Languages : en
Pages : 195
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Book Description
Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders examines the non-invasive application of electrical stimulation of the brain to treat neurological disorders, and to enhance individual/group performance. This volume discusses emerging electro-technologies such as transcranial direct current/alternating current electric fields and pulsed magnetic fields to treat many of these common medical problems. Chapters begin by examining foundations of electromagnetic theory and wave equations that underly these technologies before discussing methods to treat disorders, the impact of technology and mental health and artificial intelligence. Discussing over 40 neurological diseases, this book presents coverage of techniques to treat stroke, epilepsy, Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, depression, schizophrenia, and many other diseases of the nervous system. Compares techniques so users can select ideal methods for their experiment Provides a focused tutorial introduction to core diseases of the nervous system, including stroke, epilepsy, Alzheimer’s, Parkinson’s, head and spinal cord trauma, schizophrenia, and more Covers more than 40 diseases, from foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics and neuroscience Provides walk-through boxes that guide students step-by-step through the experiment
