The selection and use of essential in vitro diagnostics

The selection and use of essential in vitro diagnostics PDF Author:
Publisher: World Health Organization
ISBN: 9240019103
Category : Medical
Languages : en
Pages : 380

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Book Description

The selection and use of essential in vitro diagnostics

The selection and use of essential in vitro diagnostics PDF Author:
Publisher: World Health Organization
ISBN: 9240019103
Category : Medical
Languages : en
Pages : 380

Get Book Here

Book Description


The selection and use of essential in vitro diagnostics

The selection and use of essential in vitro diagnostics PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240081097
Category : Medical
Languages : en
Pages : 237

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Book Description
Technical report of the fourth meeting of the WHO Strategic Advisory Group of Experts on In Vitro Diagnostics, 2022 (including the fourth WHO model list of essential in vitro diagnostics (EDL 4)). This report also includes the applications received for the EDL 4 and a summary of the deliberations and recommendations by the SAGE IVD members and the methodologist that assessed the supportive evidence for the EDL 4 applications.

The selection and use of essential medicines

The selection and use of essential medicines PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240089268
Category : Medical
Languages : en
Pages : 940

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Book Description
The 24th meeting of the WHO Expert Committee on Selection and Use of Essential Medicines was held in Geneva, Switzerland, from 24 to 28 April 2023. The Committee considered 85 applications proposing additions, changes and deletions of medicines, medicine classes and formulations on the Model Lists of Essential Medicines. The Committee evaluated the scientific evidence for effectiveness, safety and cost- effectiveness of the medicines in question. The Committee also considered a review of the age-appropriateness of formulations of essential medicines for children, the AWaRe classification of antibiotics, and other matters relevant to the selection and use of essential medicines.

Selection of essential in vitro diagnostics at country level using the WHO Model List of Essential In Vitro Diagnostics to develop and update a national list of essential in vitro diagnostics

Selection of essential in vitro diagnostics at country level using the WHO Model List of Essential In Vitro Diagnostics to develop and update a national list of essential in vitro diagnostics PDF Author:
Publisher: World Health Organization
ISBN: 9240030921
Category : Medical
Languages : en
Pages : 64

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Book Description


Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

Biomarkers, Diagnostics and Precision Medicine in the Drug Industry PDF Author: Abdel Halim
Publisher: Academic Press
ISBN: 0128161221
Category : Medical
Languages : en
Pages : 296

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Book Description
The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management. - Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side - Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management - Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas and includes more than 200 illustrations

First WHO Model List of Essential In Vitro Diagnostics

First WHO Model List of Essential In Vitro Diagnostics PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241210265
Category : Medical
Languages : en
Pages : 73

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Book Description
The objective of the list is to help countries develop or update their national essential diagnostics lists, raise awareness and political will, guide procurement and regulation policies and improve access to the most important in vitro diagnostics that all countries need to make available to their populations, particularly in low-resourced countries. It will also contribute towards health systems strengthening and realizing universal health coverage.

Guidance on global monitoring for diabetes prevention and control

Guidance on global monitoring for diabetes prevention and control PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240102248
Category : Medical
Languages : en
Pages : 94

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Book Description
The guidance provides a comprehensive framework to support countries in tracking and managing diabetes prevention, care, and outcomes. This document outlines indicators across four domains: health system determinants, service delivery, risk factors, and outcomes/impacts. The guidance helps countries align their monitoring efforts with WHO’s global diabetes targets, Global Diabetes Compact, and relevant global NCD targets. It emphasizes the importance of collecting, analyzing, and utilizing data to inform policy and resource allocation. Specific indicators measure aspects like access to essential medications, prevalence of key risk factors, and control of blood glucose and blood pressure. Each indicator includes detailed metadata, which outlines definitions, data sources, and methods of estimation, ensuring standardized data collection and reliable comparisons across countries. Through structured monitoring, the framework aids countries in evaluating their diabetes interventions, identifying gaps, and prioritizing resources. Additionally, the guidance supports countries in meeting the Sustainable Development Goals related to reducing noncommunicable diseases and improving universal health coverage. The guidance encourages adaptation to national contexts, emphasizing the integration of innovative data collection methods and digital technologies to improve data quality and accessibility.

Report of the first WHO global meeting on skin-related neglected tropical diseases, Geneva, Switzerland, 27-31 March 2023

Report of the first WHO global meeting on skin-related neglected tropical diseases, Geneva, Switzerland, 27-31 March 2023 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240091335
Category : Medical
Languages : en
Pages : 95

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Book Description
The World Health Organization (WHO) held its inaugural global meeting on skin-related neglected tropical diseases (skin NTDs) on 27–31 March 2023, convening more than 800 global experts, stakeholders and partners. The aim of the meeting was to discuss the progress and challenges of integrating control and management of skin NTDs at the country level, in alignment with the NTD road map 2021–2030 (“the road map”) and the companion road map document on skin NTDs (“the skin NTD framework”). Skin diseases rank among the top reasons for outpatient visits and often lead to long-term disability, stigmatization and mental health issue and half of the 20 NTDs present with skin manifestations. The objectives of the meeting were centred on sharing experiences in country-level integration, showcasing research advances, implementation of the skin NTD framework and strengthening networking among experts. Participants included skin NTD specialists, representatives of health ministries, nongovernmental organizations, academic institutions and WHO. Key messages highlighted the importance of the NTD road map, emphasizing three implementation pillars: accelerating programmatic action, intensifying cross-cutting approaches, and changing operational models and culture to support country ownership. Key actions arising from the meeting were to enhance advocacy and visibility of NTDs, their inclusion into critical global policy documentation and in global health mechanisms. The global community was urged to increase NTD investments to meet the road map targets for 2030, emphasizing digital technologies, enhanced diagnostics and advances in new treatments. The second global skin NTD meeting is scheduled for 24-26 March 2025 at WHO headquarters in Geneva. The path forward is clear: we must strengthen collaborations and amplify efforts towards the 2030 NTD road map targets.

Global breast cancer initiative implementation framework

Global breast cancer initiative implementation framework PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240065989
Category : Medical
Languages : en
Pages : 118

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Book Description
Breast cancer is the most common cancer worldwide and the leading cause of cancer deaths among women, disproportionately affecting low- and middle-income countries. The Global Breast Cancer Initiative strives to reduce breast cancer mortality by 2.5 percent per year, which over a 20-year period can save 2.5 million lives. The purpose of this core technical package is to outline a pathway for incremental, sustainable improvements tailored to country-specific needs based on three key strategies and objectives: health promotion and early detection; timely diagnosis; and comprehensive breast cancer management. This document provides a common framework linking policy makers, stakeholders, the clinical community, program managers and civil society to evidence-based systematic approaches that can facilitate health systems strengthening and reduce inequities in women’s health throughout their life cycles.

Achieving Equity in Neurological Practice

Achieving Equity in Neurological Practice PDF Author: Bruce Ovbiagele
Publisher: Springer Nature
ISBN: 303162727X
Category :
Languages : en
Pages : 469

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Book Description