The Role of Transforming Growth Factor Beta in Cancer Progression and Its Possible Therapeutic Use

The Role of Transforming Growth Factor Beta in Cancer Progression and Its Possible Therapeutic Use PDF Author: Alfandy
Publisher:
ISBN:
Category : Biology
Languages : en
Pages : 31

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The Role of Transforming Growth Factor Beta in Cancer Progression and Its Possible Therapeutic Use

The Role of Transforming Growth Factor Beta in Cancer Progression and Its Possible Therapeutic Use PDF Author: Alfandy
Publisher:
ISBN:
Category : Biology
Languages : en
Pages : 31

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Book Description


Transforming Growth Factor-Beta in Cancer Therapy, Volume II

Transforming Growth Factor-Beta in Cancer Therapy, Volume II PDF Author: Sonia B. Jakowlew
Publisher: Springer Science & Business Media
ISBN: 1597452939
Category : Medical
Languages : en
Pages : 785

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Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts. The companion volume details the role of TGF- ß on basic and clinical biology.

Transforming Growth Factor-Beta in Cancer Therapy, Volume I

Transforming Growth Factor-Beta in Cancer Therapy, Volume I PDF Author: Sonia B. Jakowlew
Publisher: Springer Science & Business Media
ISBN: 1588297144
Category : Medical
Languages : en
Pages : 726

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Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. This volume’s companion, Cancer Treatment in Therapy, examines transforming growth factor- ß in other developing and advanced cancers and methods of treatment and therapy.

Transforming Growth Factor-Beta in Cancer Therapy, Volume I

Transforming Growth Factor-Beta in Cancer Therapy, Volume I PDF Author: Sonia B. Jakowlew
Publisher: Springer Science & Business Media
ISBN: 1597452920
Category : Medical
Languages : en
Pages : 726

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Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. This volume’s companion, Cancer Treatment in Therapy, examines transforming growth factor- ß in other developing and advanced cancers and methods of treatment and therapy.

The TGF-[beta] Family

The TGF-[beta] Family PDF Author: Rik Derynck
Publisher: CSHL Press
ISBN: 0879697520
Category : Transforming growth factors-beta
Languages : en
Pages : 1108

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Book Description
Transforming growth factor-[beta] (TGF-[beta]), identified nearly three decades ago, is a secreted polypeptide that functions in critical cell cycle processes, including cellular proliferation, differentiation, and development: It belongs to a large protein family that, in humans, contains 33 members, including activins, inhibins, bone morphogenetic proteins, growth and differentiation factors, and Mullerian inhibiting substance. This volume draws on the world's leading laboratories to comprehensively cover all aspects of the biology of TGF-[beta] and related factors. In addition to providing historical and background information, it describes the cell biology and signaling pathways of TGF-[beta] members in detail, including the roles of TGF-[beta] factors in the development and physiology of humans and model organisms. The last few chapters are devoted to the role of TGF-[beta] members in cancer and other diseases, as well as the possibilities for therapeutics based on knowledge of signaling pathways and macromolecular structures. It serves as a comprehensive reference work for both specialists and researchers less familiar with the field.

Clinical Applications of TGF-Beta

Clinical Applications of TGF-Beta PDF Author: Gregory R. Bock
Publisher: John Wiley & Sons
ISBN: 0470514078
Category : Science
Languages : en
Pages : 264

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Book Description
TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound healing.

Tumor Progression and Therapeutic Resistance

Tumor Progression and Therapeutic Resistance PDF Author: Wafik S. El-Deiry
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 222

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Book Description
This volume presents the entire breadth of translational cancer research and brings together members of academia and industry in the expectation of accelerating interactions and progress in the field. A variety of key topics are presented, beginning with discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), early detection, monitoring progression, understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays, mechanism determination, target validation, therapeutic window and some progress in clinical trials for more advanced agents and targets.

Transforming Growth Factor-Beta in Cancer Therapy, Volume I

Transforming Growth Factor-Beta in Cancer Therapy, Volume I PDF Author: Sonia B. Jakowlew
Publisher: Humana Press
ISBN: 9781588297143
Category : Medical
Languages : en
Pages : 0

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Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. This volume’s companion, Cancer Treatment in Therapy, examines transforming growth factor- ß in other developing and advanced cancers and methods of treatment and therapy.

TGF-β in Human Disease

TGF-β in Human Disease PDF Author: Aristidis Moustakas
Publisher: Springer Science & Business Media
ISBN: 4431544097
Category : Science
Languages : en
Pages : 463

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Book Description
Transforming growth factor-β (TGF-β) is a secreted polypeptide with multifunctional properties manifested during embryonic development, adult organ physiology, and pathobiology of major diseases, including cancer and fibrotic and cardiovascular diseases. The signaling pathway of TGF-β now is rather well understood. Continuing revelations in the mechanisms of action of TGF-β provide specific mechanistic examples of how human cells lose their controlled function and behave wrongly during the development of diverse diseases. Equally important, however, is the current promise of exploiting the TGF-β pathway in combating human disease. This book comprehensively covers major areas of human disease where the involvement of TGF-β is firmly established. Simultaneously, the book highlights major gaps in knowledge and the future directions of research that can benefit human medical science. The core set of diseases where TGF-β action is well documented and are included in the book are cancer and cardiovascular and fibrotic disorders. The central aim of the book is to stimulate young scientists to enter the prolific TGF-β field and find new solutions to the problems remaining in this area of study. For this purpose the book provides authoritative educational chapters that furnish a good introduction to the field for young doctoral students, postdocs, and clinical fellows. The book also serves as a valuable reference for the aficionados in the field, who can find accessible and well-illustrated material for their teaching and lecturing activities, via which the importance of TGF-β biology is disseminated to the world of science and to the public.

Transforming Growth Factor-Beta in Cancer Therapy, Volume II

Transforming Growth Factor-Beta in Cancer Therapy, Volume II PDF Author: Sonia B. Jakowlew
Publisher: Humana Press
ISBN: 9781588297150
Category : Medical
Languages : en
Pages : 786

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Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts. The companion volume details the role of TGF- ß on basic and clinical biology.