The Role of the Nuclear Matrix in the Organization and Control of DNA Replication in Eucaryotes PDF Download
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Author: Drew Mark Pardoll
Publisher:
ISBN:
Category :
Languages : en
Pages : 232
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Book Description
Author: Drew Mark Pardoll
Publisher:
ISBN:
Category :
Languages : en
Pages : 232
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Book Description
Author: R. Curtis Bird
Publisher: Elsevier
ISBN: 0080537812
Category : Science
Languages : en
Pages : 317
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Book Description
Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology. * Mechanisms of interaction between nuclear structure and genes * Gene expression regulation by elements of the nuclear matrix * How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Author: Ronald Berezney
Publisher: Elsevier
ISBN: 9780123846204
Category : Medical
Languages : en
Pages : 1096
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Book Description
Research on the nuclear matrix has grown enormously since Bereney and Coffey first reported its isolation and initial characterization in 1974. Since then, more than 1000 papers have been published on the subject by numerous workers around the world. This is the first book devoted to reviewing the major developments in this growing field. Key Features * The chapters cover a variety of topics, including: * Isolation of the nuclear matrix * Nuclear structure morphology in situ * Structural domains of the nuclear matrix and its components * Biochemistry and molecular biology of the matrix proteins and associated DNA and RNA * Functional properties associated with the nuclear matrix * DNA replication * Transcription * RNA splicing * Transcription regulation * Intranuclear and nucleocytoplasmic transport and targeting * Cell cycle regulation
Author: Ronny Jacobus Gerardus Opstelten
Publisher:
ISBN: 9789090019000
Category : DNA.
Languages : en
Pages : 145
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Book Description
Author: Samuel H. Wilson
Publisher: CRC Press
ISBN: 9780936923338
Category : Science
Languages : en
Pages : 476
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Book Description
This series provides, in two volumes, a complete and exhaustive review of the subject of the eukaryotic nucleus, the site of the DNA. The focus of the book is how the information in the DNA is transcribed, accessed and maintained.
Author: K Leon
Publisher: Elsevier
ISBN: 0323148999
Category : Science
Languages : en
Pages : 476
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Book Description
Aspects of Nuclear Structure and Function deals with various aspects of nuclear structure and function and covers topics ranging from the ultrastructure of the female gamete to the structure, biochemistry, and functions of the nuclear envelope. Banding patterns in chromosomes, histones and nonhistone proteins, and the transfer of genetic information in polytene cells are also discussed. This book is comprised of six chapters and begins by presenting a comparative view of some aspects of the ultrastructure of the vegetative (growth) aspects of oogenesis, with emphasis on microtubules, intercellular bridges of differentiating oocytes, and vitellogenesis as well as accessory structures of the egg envelope. The following chapters explore the structure, biochemistry, and functions of the nuclear envelope; banding patterns in chromosomes; chromosomal proteins (histones and nonhistone proteins); transfer of genetic information in polytene cells; and the intracellular biology of DNA polymerases in eukaryotic cells, their association with the nucleus, and how this association changes during the mitotic cell cycle. The relationship between eukaryotic DNA polymerases and DNA replication is also examined. This monograph should be a valuable resource for biochemists.
Author: A. De Recondo
Publisher: Springer Science & Business Media
ISBN: 1468443976
Category : Medical
Languages : en
Pages : 361
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Book Description
DNA replication in eukaryotes is an important field, particular ly because of its direct impact on the study of cancer. The under standing of molecular mechanisms of replication and their regulation should allow a better comprehension of the alterations that lead to the proliferation of tumor cells and to error-prone repair in cells exposed to radiation or chemical carcinogens. During the last several years, many enzymes and proteins which participate in replication of DNA in eukaryotic cells have been identified, isolated and characterized. New concepts in chromatin structure have refocused attention on the study of replication of DNA complexed with his tones and non-histone chromosomal proteins. However, progress has been noticeably slower than for prokaryotes, essentially because of the difficulty in genetic analysis of eukaryo tic DNA replication. In June 1980, a workshop was organized in Cargese, Corsica (France) to facilitate exchanges of information between workers spe cializing in prokaryotes and those specializing in eukaryotes, and to allow discussion of new experimental approaches. With this in mind, special interest has been taken in the origin and termination of chromosome cycles and how they are controlled.
Author: Patrick Heun
Publisher:
ISBN:
Category :
Languages : en
Pages : 115
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Book Description
Author: Cirilo Dumag Cabradilla
Publisher:
ISBN:
Category :
Languages : en
Pages : 348
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Book Description
Author: J. A. Bryant
Publisher: CUP Archive
ISBN: 9780521300469
Category : Science
Languages : en
Pages : 280
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Book Description
Control points within the cell cycle. The organization of replicons. Enzymic controls of DNA replication. DNA replication in relation to DNA C values. Chromatin structure, gene espression and the cell cycle. Changes in chromatin structure during the cell cycle. The cytoskeleton and the cell cycle. Growth substances, calcium and the regulation of cell division. Regulation of the cell division cycle in cultured plant cells. Genetic and epigenetic control of the plant cell cycle. The control of the cell cycle in relation to floral induction. The DNA endoredduplication cycles. The chloroplast division cycle and its relationship to the cell division cycle.
