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Author: Louis Cotoni
Publisher:
ISBN:
Category : Pneumococcal Infections
Languages : en
Pages : 242
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Book Description
Author: Louis Cotoni
Publisher:
ISBN:
Category : Pneumococcal Infections
Languages : en
Pages : 242
Get Book Here
Book Description
Author: Louis Cotoni
Publisher:
ISBN:
Category :
Languages : en
Pages : 218
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Book Description
Author: Harold P. Lambert
Publisher: Royal Society of Medicine Press
ISBN:
Category : Medical
Languages : en
Pages : 132
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Book Description
Author: National Institute of Allergy and Infectious Diseases (U.S.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 16
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Book Description
Author: Guangchun Bai
Publisher: Frontiers Media SA
ISBN: 2889452786
Category :
Languages : en
Pages : 112
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Book Description
Streptococcus pneumoniae has been for decades the number one bacterial killer of children in the world. Although vaccination with pneumococcal vaccines [PCV7, PCV10, and PCV13 (children) or PPSV23 (adults)] has helped decrease the burden of pneumococcal disease (PD), mortality remains high. Therefore, pathogenesis studies are still key toward our understanding of PD and its control. The introduction of pneumococcal vaccines has also created a niche for vaccine-escape clones. Moreover, the rise of multi-drug resistant clones around the world has also posed a serious threat in recent years. The proposed special issue of Frontiers in Cellular and Infection Microbiology highlights many of the recent advances that have been made in pneumococcal pathogenesis, colonization and antibiotic resistance by groups in Latino America, Europe, and the USA.
Author: Jorge Eugenio Vidal
Publisher: Frontiers Media SA
ISBN: 2889749398
Category : Science
Languages : en
Pages : 125
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Book Description
Streptococcus pneumoniae (the pneumococcus) is a commensal of the human nasopharynx during childhood, but also causes a variety of infections, such as otitis media (OM), pneumonia, bacteremia, and meningitis, mainly affecting infants, the elderly and immunocompromised patients. Pneumococcal pneumonia alone produces more child deaths, every year, than any other bacterial disease worldwide. To date, more than 90 distinct capsular serotypes have been identified. Current pneumococcal conjugate vaccines (PCV) protect against 7, 10 or 13 different pneumococcal types. These vaccines have decreased the burden of pneumococcal disease produced by vaccine types but provide poor protection against non-vaccine serotypes. Additionally, the increasing prevalence of multi-drug resistant S. pneumoniae strains results in more challenge for treatment of pneumococcal infections. Therefore, it is imperative to continue investigating the molecular pathogenesis of the pneumococcus. There are currently a variety of key virulence determinants known to be involved in pathogenesis of pneumococcal disease. Virulence factors and host immune defense are major players during pathogen - host interactions. Some metabolic pathways have also been shown to play a role in pneumococcal pathogenesis. These metabolic pathways include proteins involved in copper efflux, arginine metabolism, and zinc homeostasis. From the human host side, new host factors have been found to play essential roles in clearance of S. pneumoniae during infection, such as microRNA-155. Moreover, biofilm-like structures may alter both pneumococcal phenotypes and the host immunity during nasopharyngeal carriage and/or during disease. Understanding the interaction between pneumococcus and its human host is a key to combat pneumococcal infections. It has been well known for several years that pneumococcal pneumonia is worsened during poly-microbial infection. During the past few years, rapid progress has been made in this area. For example, it was recently shown that influenza A virus increases pneumococcal nasal colonization and it is a risk factor for pneumococcal pneumonia. Other important respiratory viruses and bacterial pathogens, such as Moraxella catarrhalis and Haemophilus influenzae, appear to increase the risk of pneumococcal colonization and disease. A better understanding of the molecular mechanism leading to these pathogenic synergisms will provide a fundamental basis for prevention and treatment of secondary pneumococcal infection. The elderly population is generally more susceptible to pneumococcal infections. In addition to their declined immunity, alteration of the microbiome seen in the elderly may play a role for the susceptibility of infection. Research with the elderly or using elderly animal infection models will largely enhance our knowledge and significantly reduce the morbidity and mortality caused by pneumococcal infections.
Author:
Publisher: ScholarlyEditions
ISBN: 1464904855
Category : Medical
Languages : en
Pages : 58
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Book Description
Pneumococcal Infections: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Pneumococcal Infections in a concise format. The editors have built Pneumococcal Infections: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pneumococcal Infections in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pneumococcal Infections: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Robert Austrian
Publisher: University of Pennsylvania Press
ISBN: 1512800139
Category : Medical
Languages : en
Pages : 180
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Book Description
Because of the high fatality rate of untreated pneumococcal pneumonia, both the disease and its principal cause, the pneumococcus, were objects of intense scrutiny by physicians and bacteriologists during the last two decades of the nineteenth century and the first half of the twentieth. As a result, scientists learned much of the fundamental importance to microbiology, immunology, and genetics while developing the pneumococcal vaccine.
Author: L. Cotoni
Publisher:
ISBN:
Category : Pneumoccocal infections
Languages : en
Pages : 218
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Book Description
Author: Roderick Heffron
Publisher: Harvard University Press
ISBN: 9780674674448
Category : Pneumonia
Languages : en
Pages : 1110
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Book Description
