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Author: James J. Nordlund
Publisher: John Wiley & Sons
ISBN: 140515733X
Category : Medical
Languages : en
Pages : 1333
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Book Description
The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.
Author: James J. Nordlund
Publisher: John Wiley & Sons
ISBN: 140515733X
Category : Medical
Languages : en
Pages : 1333
Get Book Here
Book Description
The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.
Author: M. Lynn Lamoreux
Publisher: John Wiley & Sons
ISBN: 1444319663
Category : Science
Languages : en
Pages : 312
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Book Description
Serving the needs of pigment cell biologists, cellular physiologists, developmental geneticists, researchers interested in melanoma and more, this new book showcases a blend of new technologies and new insights in the field of pigmantary genetics of mice, with comparative information on other animals. Graduate students can learn here the terminology and scope of the field, and animal fanciers can discover the genetics behind common color variants of mammals. The book is hailed for being written by four of the premier scientists in the field. These authors aim to present the molecular /cellular work in the context of phenotype and the interacting functions of genes that direct the development and function of one biological system. For other researchers, the depth of genetic knowledge on the pigmantary system makes it a valuable model for the study of other systems.
Author: Giuseppe Prota
Publisher: Academic Press
ISBN: 0323139396
Category : Science
Languages : en
Pages : 305
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Book Description
This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.
Author: Roger D. Cone
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 416
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Book Description
In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.
Author: Ashley H. Robins
Publisher: Cambridge University Press
ISBN: 9780521020206
Category : Science
Languages : en
Pages : 268
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Book Description
Skin color is perhaps the most decisive and abused physical characteristic of humankind. This book presents a multidisciplinary overview of how and why human populations vary so markedly in their skin color. The biological aspects of the pigment cell and its production of melanin are reviewed. The functions of melanin in the skin, brain, eye and ear are considered, and the common clinical abnormalities of pigmentation, such as albinism, are described and illustrated. Detailed reflectance data from worldwide surveys of skin color are also presented. Next, historical and contemporary backgrounds of the phenomenon are explored in relation to the so-called color problem in society. Finally, the possible evolutionary forces that shape human pigmentation are assessed.
Author: Jean-Paul Ortonne
Publisher: Springer Science & Business Media
ISBN: 1461592720
Category : Medical
Languages : en
Pages : 774
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Book Description
Leukoderma is a generic term for any pigmentary dilution, be it congenital or acquired, circumscribed or generalized, devoid of or partially lacking in pig mentation. In the approach to the diagnosis of leukoderma, we have generally first considered the age of onset, whether leukoderma was congenital or ac quired, the extent and pattern of involvement, and the degree of pigmentary dilution. The organization of this monograph reflects this approach. For ex ample, we have separated the section devoted to various disease entities into diffuse and circumscribed leukoderma and the latter into various etiologies such as genetic, metabolic, infectious, and endocrinologic. One of several justifications for this monograph is to present an approach to the diagnosis of leukoderma, as detailed in Part II. In formulating a guide for the physician, we have found some limitations to our previous approach; we therefore offer the following new classification based upon a clini cal-pathologic correlation. This could provide the means to describe both the clinical and pathologic findings in one term.
Author: Somesh Gupta
Publisher: John Wiley & Sons
ISBN: 1118937414
Category : Medical
Languages : en
Pages : 533
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Book Description
Practical guidance based on expert experience and evidence for developing management strategies for vitiligo This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world’s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease’s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. Thoroughly guides those involved in the clinical aspects of vitiligo Aids diagnosis and classification of severity Balances evidence and experience Compiled by world-leading expert editors Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.
Author: Nina G. Jablonski
Publisher: Univ of California Press
ISBN: 0520283864
Category : Science
Languages : en
Pages : 280
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Book Description
This book investigates the social history of skin color from prehistory to the present, showing how our body's most visible trait influences our social interactions in profound and complex ways. The author begins with the biology and evolution of skin pigmentation, explaining how skin color changed as humans moved around the globe. She explores the relationship between melanin pigment and sunlight, and examines the consequences of rapid migrations, vacations, and other lifestyle choices that can create mismatches between our skin color and our environment. Richly illustrated, this book explains why skin color has come to be a biological trait with great social meaning-- a product of evolution perceived by culture. It considers how we form impressions of others, how we create and use stereotypes, how negative stereotypes about dark skin developed and have played out through history. Offering examples of how attitudes about skin color differ in the U.S., Brazil, India, and South Africa, the author suggests that a knowledge of the evolution and social importance of skin color can help eliminate color-based discrimination and racism.
Author: Kambiz Thomas Moazed
Publisher: Springer Nature
ISBN: 3030457567
Category : Medical
Languages : en
Pages : 257
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Book Description
The iris is a circular, pigmented tissue that separates the anterior chamber of the eye from the posterior chamber. It has a crucial role on controlling the amount of the light entering the eye through its central opening “the pupil". The Iris has multiple important functions that support and provide image clarity on the retina. However, it is a largely neglected part of the eye, compared to the cornea lens, retina, and optic nerve, and has not been focused on in a comprehensive way until now. The Iris: Understanding the Essentials, combines different aspects of scientific information from a variety of fields, such as anatomy, histopathology, molecular biology, electron microscopy and other diagnostic modalities. Each chapter will include pearls and summary points, and this multi-disciplinary approach helps the clinician diagnose and treat the large variety of diseases that affect the iris, with the main emphasize on pigmentary pathological changes that can affect the color of the eye. Written as a reference review book for universities, practicing ophthalmologists, Ophthalmology residents, pharmaceutical companies and diagnostic equipment manufacturing companies this book summarizes the information in an easy-to-use manner to help the reader better understand the iris, iris structure, physiology and function.
Author: Jan Borovansky
Publisher: John Wiley & Sons
ISBN: 3527644555
Category : Science
Languages : en
Pages : 395
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Book Description
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
