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Author: Helmut Schiessel
Publisher: CRC Press
ISBN: 9814241652
Category : Science
Languages : en
Pages : 420
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Book Description
Biophysics is a new way of looking at living matter. It uses quantitative experimental and theoretical methods to open a new window for studying and understanding life processes. This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.
Author: Helmut Schiessel
Publisher: CRC Press
ISBN: 9814241652
Category : Science
Languages : en
Pages : 420
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Book Description
Biophysics is a new way of looking at living matter. It uses quantitative experimental and theoretical methods to open a new window for studying and understanding life processes. This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.
Author: Ronald Hancock
Publisher: Humana Press
ISBN: 9781493916795
Category : Science
Languages : en
Pages : 0
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Book Description
This volume presents detailed, recently-developed protocols ranging from isolation of nuclei to purification of chromatin regions containing single genes, with a particular focus on some less well-explored aspects of the nucleus. The methods described include new strategies for isolation of nuclei, for purification of cell type-specific nuclei from a mixture, and for rapid isolation and fractionation of nucleoli. For gene delivery into and expression in nuclei, a novel gentle approach using gold nanowires is presented. As the concentration and localization of water and ions are crucial for macromolecular interactions in the nucleus, a new approach to measure these parameters by correlative optical and cryo-electron microscopy is described. The Nucleus, Second Edition presents methods and software for high-throughput quantitative analysis of 3D fluorescence microscopy images, for quantification of the formation of amyloid fibrils in the nucleus, and for quantitative analysis of chromosome territory localization. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, The Nucleus, Second Edition seeks to serve both professionals and novices with its well-honed methods for the study of the nucleus.
Author: Ronald Hancock
Publisher: Humana Press
ISBN: 9781493916818
Category : Science
Languages : en
Pages : 237
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Book Description
This volume presents detailed, recently-developed protocols ranging from isolation of nuclei to purification of chromatin regions containing single genes, with a particular focus on some less well-explored aspects of the nucleus. The methods described include new strategies for isolation of nuclei, for purification of cell type-specific nuclei from a mixture, and for rapid isolation and fractionation of nucleoli. For gene delivery into and expression in nuclei, a novel gentle approach using gold nanowires is presented. As the concentration and localization of water and ions are crucial for macromolecular interactions in the nucleus, a new approach to measure these parameters by correlative optical and cryo-electron microscopy is described. The Nucleus, Second Edition presents methods and software for high-throughput quantitative analysis of 3D fluorescence microscopy images, for quantification of the formation of amyloid fibrils in the nucleus, and for quantitative analysis of chromosome territory localization. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, The Nucleus, Second Edition seeks to serve both professionals and novices with its well-honed methods for the study of the nucleus.
Author: M. A. Preston
Publisher: CRC Press
ISBN: 0429972644
Category : Science
Languages : en
Pages : 571
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Book Description
A graduate-level one-volume textbook and reference work on the structure and physics of atomic nuclei. Throughout this book the underlying emphasis is on how a nucleus is constituted through the interaction between the nucleons. The book is structured into three parts: the first part contains a detailed treatment of the two-nucleon force and of basic model-independent nuclear properties the second part discusses the experimental results of nuclear models and their bases in fundamental theory the third part deals in some detail with alpha-decay and fission.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Ray Mackintosh
Publisher: Johns Hopkins University Press
ISBN: 9781421403519
Category : Science
Languages : en
Pages : 0
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Book Description
The discovery of the nucleus transformed the past century and will revolutionize this one. Nuclear physics is one of the most exciting—and useful—branches of science. In medicine, it helps save lives through innovative medical technologies, such as the MRI, and in nuclear astrophysics, state-of-the-art theoretical and computer models account for how stars shine and describe how the chemical elements in the universe were formed. Now in its second edition, Nucleus tells the story of the nucleus from the early experimental work of the quiet New Zealander Lord Rutherford to the huge atom-smashing machines of today and beyond. Thoroughly revised and updated, the book includes the most current information on the radio dating of Earth and other planets in the Solar System, heavy-ion therapies, quark-gluon plasma and its relevance to black holes, and clarification of ab initio calculations of atomic nuclei. Lavishly illustrated and with lively prose and captivating details, this book unravels the scientific mysteries that surround the subject of the nucleus. Anyone with even a passing interest in science will delight in this guide to the nuclear age.
Author: I. Robin A. Barraco
Publisher: CRC Press
ISBN: 100000595X
Category : Science
Languages : en
Pages : 448
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Book Description
First Published in 1994, this book provides a comprehensive, up-to-date compilation of reviews of recent literature on the anatomy, physiology, and pharmacology of the nucleus of the solitary tract (NTS). The chapters are written by internationally recognized experts in the field and include never-before-published data, diagrams, and figures.
Author: Heinz Steiner
Publisher: Academic Press
ISBN: 008091215X
Category : Medical
Languages : en
Pages : 729
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Book Description
The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. - Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction - Features a truly international cast of the preeminent researchers in the field - Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Author: Sir William James Erasmus WILSON
Publisher:
ISBN:
Category :
Languages : en
Pages : 610
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Book Description
Author: Thomas D. Pollard
Publisher: Elsevier Health Sciences
ISBN: 0323400027
Category : Science
Languages : en
Pages : 900
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Book Description
The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. - Clearly written format incorporates rich illustrations, diagrams, and charts. - Uses real examples to illustrate key cell biology concepts. - Includes beneficial cell physiology coverage. - Clinically oriented text relates cell biology to pathophysiology and medicine. - Takes a mechanistic approach to molecular processes. - Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. - Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. - Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. - Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail. - Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices.
