The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders PDF Author: Joseph D. Buxbaum
Publisher: Academic Press
ISBN: 012391924X
Category : Medical
Languages : en
Pages : 494

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Book Description
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders PDF Author: Joseph D. Buxbaum
Publisher: Academic Press
ISBN: 012391924X
Category : Medical
Languages : en
Pages : 494

Get Book Here

Book Description
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

The Neurobiology of Autism

The Neurobiology of Autism PDF Author: Margaret L. Bauman
Publisher: JHU Press
ISBN: 9780801880476
Category : Medical
Languages : en
Pages : 428

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Book Description
In the decade since the first edition of The Neurobiology of Autism was published, research has revealed valuable new information about the nature and origins of autism, including genetics and abnormalities in such neurotransmitters as acetylcholine and serotonin. For this long-anticipated new edition, neurologists Margaret L. Bauman and Thomas L. Kemper bring together leading researchers and clinicians to present the most current scientific knowledge and theories about autism. The contributors cover genetics, imaging studies, physiology, neuroanatomy and neurochemistry, immunology, brain function, the epidemiology of the disease, and related disorders. Thoroughly updated, The Neurobiology of Autism remains the best single-volume work on the wide array of research being conducted into the causes, characteristics, and treatment of autism. Contributors: George M. Anderson, Yale Child Study Center; Tara L. Arndt, University of Rochester Medical Center (URMC); Trang Au, University of Massachusetts Medical School (UMMC); Jocelyne Bachevalier, University of Texas Health Science Center; Irina N. Bespalova, Seaver Autism Research Center, Mt. Sinai School of Medicine (SARC); Gene J. Blatt, Boston University School of Medicine (BUSM); Susan E. Bryson, IWK Health Centre–Dalhousie University; Timothy M. Buie, Massachusetts General Hospital (MGH); Joseph D. Buxbaum, SARC; Kathryn M. Carbone, The Johns Hopkins University School of Medicine (JHUSM); Diane C. Chugani, Wayne State University; Daniel F. Connor, UMMC; Edwin H. Cook, Jr., University of Chicago; S. Hossein Fatemi, University of Minnesota Medical School; Susan E. Folstein, Tufts University School of Medicine; Eric Fombonne, McGill University; Randi Jenssen Hagerman, UC Davis Medical Center; Elizabeth Petri Henske, Fox Chase Cancer Center, Philadelphia; Jeannette J. A. Holden, Queen's University; Ronald J. Killiany, BUSM; Omanand Koul, UMMC; Mandy Lee, Newcastle General Hospital, U.K.; Xudong Liu, Queen's University; Tara L. Moore, BUSM; Mark B. Moss, BUSM; Karin B. Nelson, National Institute of Neurological Disorders and Stroke; Phillip G. Nelson, National Institute of Child Health and Human Development; Elaine Perry, Newcastle General Hospital; Jonathan Pevsner, JHUSM; Mikhail V. Pletnikov, JHUSM; Stephen W. Porges, University of Illinois at Chicago; Lucio Rehbein, Universidad de la Frontera, Chile; Jennifer Reichert, SARC; Patricia M. Rodier, URMC; Beth Rosen-Sheidley, MGH; Susan L. Smalley, UCLA Neuropsychiatric Research Institute; Ronald J. Steingard, UMMC; Helen Tager-Flusberg, BUSM; Gary L. Wenk, University of Arizona; Andrew W. Zimmerman, JHUSM

Autism Spectrum Disorder

Autism Spectrum Disorder PDF Author: Susan P. Sherkow
Publisher: Rowman & Littlefield
ISBN: 0765708639
Category : Psychology
Languages : en
Pages : 233

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Book Description
Autism Spectrum Disorder: Perspectives from Psychoanalysis is written by practicing child psychoanalysts with extensive experience treating children with autistic spectrum disorders (ASD) and uneven development. The authors bridge the gap between a psychodynamic approach to ASD and burgeoning data from the fields of neurobiology and neurofunction. Based on current research showing neuroplasticity of the brain, the authors posit that treating ASD through intensive engagement of caregiver and child makes possible the successful psychoanalytic treatment of a neurobiological disorder. To this end, the authors examine both the clinical dynamics of their treatments and the possible impact of the treatment on neurobiological processes. Detailed case studies of children treated by the authors comprise the heart of the book. The cases emphasize the importance of engaging these young children intensively with the social world, first of their caregivers and then their peers, while also helping child and caregiver make sense of the child’s “nonsense” behavior through insight into their inner worlds. The authors explain how and why such treatment works through examining the processes by which infant and caregiver learn to know each other and how a baby comes to know the world. This approach emphasizes the intimate connection between infant and caregiver in forming the emotional, cognitive, attentional, and interpersonal experiences that give a child the ability to make meaning and grow. In addition, this volume presents a selective summary of the neurobiological research in the area of ASD to provide the reader with the related neurobiological and psychological factors. This underscores the thesis that ASD is a potentially reversible neurodevelopmental disorder with experiential and psychological consequences, and lays groundwork for an integrated treatment approach with psychoanalysis at its core.

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability PDF Author: Carlo Sala
Publisher: Academic Press
ISBN: 0128005335
Category : Medical
Languages : en
Pages : 396

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Book Description
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. - Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities - Describes the genes implicated in autistic spectrum disorders and their function - Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies - Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture

Handbook of Medical Neuropsychology

Handbook of Medical Neuropsychology PDF Author: Carol L. Armstrong
Publisher: Springer Science & Business Media
ISBN: 1441913645
Category : Psychology
Languages : en
Pages : 555

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Book Description
This handbook celebrates the abundantly productive interaction of neuropsychology and medicine. This interaction can be found in both clinical settings and research l- oratories, often between research teams and clinical practitioners. It accounts for the rapidity with which awareness and understanding of the neuropsychological com- nents of many common medical disorders have recently advanced. The introduction of neuropsychology into practice and research involving conditions without obvious neurological components follows older and eminently successful models of integrated care and treatment of the classical brain disorders. In the last 50 years, with the growing understanding of neurological disorders, neuropsychologists and medical specialists in clinics, at bedside, and in laboratories together have contributed to important clinical and scienti c advances in the und- standing of the common pathological conditions of the brain: stroke, trauma, epilepsy, certain movement disorders, tumor, toxic conditions (mostly alcohol-related), and degenerative brain diseases. It is not surprising that these seven pathological con- tions were the rst to receive attention from neuropsychologists as their behavioral symptoms can be both prominent and debilitating, often with serious social and economic consequences.

Handbook of Autism Spectrum Disorder and the Law

Handbook of Autism Spectrum Disorder and the Law PDF Author: Fred R. Volkmar
Publisher: Springer Nature
ISBN: 3030709132
Category : Psychology
Languages : en
Pages : 563

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Book Description
This book addresses an important and relatively neglected topic in the scientific literature: individuals with autism spectrum disorder (ASD) who have dealings with the legal system. It examines issues and implications for autistic people, who have a significant risk for engagement with the legal system in some capacity (e.g., witness/bystander, victim, or perpetrator). Key areas of coverage include: Autistic people as victims and perpetrators of criminal activities, including violence, stalking, sexual exploitation, and cybercrime. Risks for unlawful behavior in individuals with autism and Asperger's. Legal assessment issues, such as witness protection and postconviction diagnoses. Legal outcomes for autistic people, including case law, prevention, service provisions in correctional settings, and rights and support systems. The Handbook of Autism Spectrum Disorder and the Law is an essential, comprehensive resource that explores the risk for unlawful behaviors affecting autistitc people as victims and perpetrators, as well as related issues of assessment and treatment, and outcome. It is a must-have reference for researchers, clinicians/practitioners, and graduate students in psychology, psychiatry, social work, and law, as well as professionals in such related fields, as criminology/criminal justice and the legal system.

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: David Amaral
Publisher: Oxford University Press
ISBN: 0199707472
Category : Medical
Languages : en
Pages : 1445

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Book Description
Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 150 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financial resources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology. Edited by three leading researchers, this volume contains over 80 chapters and nine shorter commentaries by thought leaders in the field, making the book a virtual "who's who" of autism research. This carefully developed book is a comprehensive and authoritative reference for what we know in this area as well as a guidepost for the next several years in all areas of autism research.

The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders PDF Author: Joseph D. Buxbaum
Publisher: Academic Press
ISBN: 0123919304
Category : Medical
Languages : en
Pages : 493

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Book Description
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. - Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions - Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Cognitive Plasticity in Neurologic Disorders

Cognitive Plasticity in Neurologic Disorders PDF Author: Joseph I. Tracy
Publisher: Oxford University Press, USA
ISBN: 0199965242
Category : Medical
Languages : en
Pages : 433

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Book Description
This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Autism Spectrum Disorder

Autism Spectrum Disorder PDF Author: Michael Fitzgerald
Publisher: BoD – Books on Demand
ISBN: 9535120379
Category : Science
Languages : en
Pages : 380

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Book Description
This book starts with a new sub category of Autism Criminal Autistic Psychopathy and school shootings. It focuses on a number of interventions, including speech and language pathology, speech and language assessment instruments, occupational therapy, improving functional language development in autism with natural gestures, communication boards etc as well as helping people with autism using the pictorial support, training of concepts of significant others, theory of mind, social concepts and a conceptual model for empowering families of children with autism cross culturally. It also examines the issue of hyperandrogenism and evidence-based treatments of autism. In terms of assessment, it focuses on psychological and biological assessment including neurotransmitters systems, structural and functional brain imaging, coping strategies of parents, examines the intertwining of language impairment, specific language impairment and ASD, as well as implicit and spontaneous Theory of Mind reading in ASD. In terms of aetiology, it focuses on genetic factors, epigenetics, synaptic vesicles, toxicity during neurodevelopment, immune system and sex differences. It also examines the link between social cognitive anatomical and neurophysiologic biomarkers and candidate genes. This book will be relevant to all mental health professionals because autism occurs in all the different areas of psychiatry and professionals who will find it helpful will be psychiatrists, psychologists, social workers, nurses, teachers and all those working with persons with Autism including parents who nowadays are interested in knowing more and more, at a detailed level about their children or adults with autism.