The Neuropharmacological Basis of Reward

The Neuropharmacological Basis of Reward PDF Author: Jeffrey M. Liebman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 456

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Book Description
This volume reviews recent major advances in reinforcement and behaviour. The contributors, all prominent physiological psychologists and behavioural pharmacologists, have extensively analysed current research on drugs, brain neurotransmitters, and reinforcement in animals. The book documents convergent evidence that implicates the nucleus accumbens and its dopaminergic afferents in reward. Controversial themes include the identity of the neurons mediating intracranial self-stimulation, and whether or not non-dopaminergic neurons can independently mediatereinforcement. Exciting new technical advances, such as conditioned place preferences, intracranial microinjection, and self-administration of drugs, as well as advanced new techniques for measuring the specificity of drug effects on reinforcement, are thoroughly explained and future research directionsoutlined.

The Neuropharmacological Basis of Reward

The Neuropharmacological Basis of Reward PDF Author: Jeffrey M. Liebman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 456

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Book Description
This volume reviews recent major advances in reinforcement and behaviour. The contributors, all prominent physiological psychologists and behavioural pharmacologists, have extensively analysed current research on drugs, brain neurotransmitters, and reinforcement in animals. The book documents convergent evidence that implicates the nucleus accumbens and its dopaminergic afferents in reward. Controversial themes include the identity of the neurons mediating intracranial self-stimulation, and whether or not non-dopaminergic neurons can independently mediatereinforcement. Exciting new technical advances, such as conditioned place preferences, intracranial microinjection, and self-administration of drugs, as well as advanced new techniques for measuring the specificity of drug effects on reinforcement, are thoroughly explained and future research directionsoutlined.

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain PDF Author: George F. Koob
Publisher: Academic Press
ISBN: 0123869595
Category : Medical
Languages : en
Pages : 351

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Book Description
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction

Neuroscience in the 21st Century

Neuroscience in the 21st Century PDF Author: Donald W. Pfaff
Publisher: Springer
ISBN: 9781493934737
Category : Medical
Languages : en
Pages : 0

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Book Description
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.

Identification of Neural Markers Accompanying Memory

Identification of Neural Markers Accompanying Memory PDF Author: Alfredo Meneses
Publisher: Elsevier
ISBN: 012416711X
Category : Psychology
Languages : en
Pages : 169

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Book Description
Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field. - Discusses the alterations of memory in diverse diseases - Includes coverage from a basic introduction of memory investigation - Reviews brain areas and neurotransmitters involved in memory - Discusses behavioral models of memory - Contains novel insights into the complexity of signaling and memory - Includes the neuropharmacological and neurobiological bases of memory

Neurobiology of Addiction

Neurobiology of Addiction PDF Author: George F. Koob
Publisher: Elsevier
ISBN: 0080497373
Category : Psychology
Languages : en
Pages : 503

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Book Description
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.· Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Substance Abuse

Substance Abuse PDF Author: Joyce H. Lowinson
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781734745
Category : Medical
Languages : en
Pages : 1454

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Book Description
The premier text on substance abuse and addictive behaviors is now in its updated and expanded Fourth Edition, with up-to-the-minute insights from more than 150 experts at the front lines of patient management and research. This edition features expanded coverage of the neurobiology of abused substances, new pharmacologic therapies for addictions, and complete information on “club drugs” such as Ecstasy. New sections focus on addiction in children, adolescents, adults, and the elderly and women’s health issues, including pregnancy. The expanded behavioral addictions section now includes hoarding, shopping, and computer/Internet abuse. Includes access to a Companion wesbite that has fully searchable text.

The Self and Social Relationships

The Self and Social Relationships PDF Author: Joanne V. Wood
Publisher: Psychology Press
ISBN: 1134954948
Category : Psychology
Languages : en
Pages : 323

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Book Description
Although the two major research areas of the "Self" and "Social Relationships" have flourished, they have done so largely independently of each other. More and more research, however, has indicated that relationships shape the nature of the self and identity, and that self-views influence interpersonal processes and the manner in which people navigate their close relationships. The integration of research on self and social relationships has proved a particularly rich one, generating some of the most creative and insightful theories in psychology. The Self and Social Relationships is the first volume that marks, expedites, and defines this exciting new research synthesis. It serves both as a platform for authors to present their latest ideas on the topic and to encourage continued integration in this emerging field. The contributions represent a diverse set of perspectives from social/personality and clinical psychology. Each chapter covers a topic that is central to the study of self and relationships, and presents some of the most exciting research programs in the field. This volume is essential reading for researchers and students in the areas of both self and relationships.

Experimental Acupuncturology

Experimental Acupuncturology PDF Author: Jaung-Geng Lin
Publisher: Springer
ISBN: 981130971X
Category : Medical
Languages : en
Pages : 212

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Book Description
This book focuses on the use of acupuncture as a possible and alternative treatment in analgesia, drug addiction, depression, itchiness, peripheral nerve regeneration, stroke, diabetes, cognitive deficits and sleep regulation. Formal recognition by WHO and UNESCO concerning the use and efficacy of acupuncture science in modern medicine has encouraged high levels of investment and commitment to research and development activities into acupuncture science from several top-level health science research and treatment institutes in China Mainland, Taiwan, Japan, Korea, France and the USA. This book aims to provide direction and guidance on how the medical community can proceed with acupuncturology in modern medical treatment and precision medicine.

Neurobiology of Opioids

Neurobiology of Opioids PDF Author: Osborne F.X. Almeida
Publisher: Springer Science & Business Media
ISBN: 3642466605
Category : Medical
Languages : en
Pages : 453

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Book Description
Dedicated to Professor Albert Herz, a leading investigator in opioid research, this book provides comprehensive information on the biology of exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an in-depth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.

Emotion and Decision Making Explained

Emotion and Decision Making Explained PDF Author: Edmund T. Rolls
Publisher:
ISBN: 0199659893
Category : Business & Economics
Languages : en
Pages : 729

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Book Description
What produces emotions? Why do we have emotions? How do we have emotions? Why do emotional states feel like something? What is the relation between emotion, and reward value, and subjective feelings of pleasure? These are just some of the question considered in this book, written by a leading neuroscientist in this field.