Author: Jerry Hanel
Publisher: Independently Published
ISBN: 9781092298797
Category :
Languages : en
Pages : 328
Book Description
Jackson and Lacey are mutants. They weren't born, they were created in a lab. The world outside doesn't know that they even exist, and corporations like Centratek want it that way. They want to keep their trained and specialized properties locked away to sell to the highest bidder.That is, until Jackson uses his illusion abilities to escape, and Lacey reaches out with her mind to find him. This sets a series of events in motion where Centratek must covertly do all they can to pluck Jackson and Lacey from the wild and return them -- dead or alive -- to the confines of the labs where they were created.Chased by a trained hunter and a ten-year-old mutant named Sniff, Jackson and Lacey flee across the USA, encountering other freed mutants, and learning to hide in plain sight. What they don't know might kill them, and their unwitting escape is the perfect dry kindling to spark a mutant/human war.
The Mutant Frequency
Author: Jerry Hanel
Publisher: Independently Published
ISBN: 9781092298797
Category :
Languages : en
Pages : 328
Book Description
Jackson and Lacey are mutants. They weren't born, they were created in a lab. The world outside doesn't know that they even exist, and corporations like Centratek want it that way. They want to keep their trained and specialized properties locked away to sell to the highest bidder.That is, until Jackson uses his illusion abilities to escape, and Lacey reaches out with her mind to find him. This sets a series of events in motion where Centratek must covertly do all they can to pluck Jackson and Lacey from the wild and return them -- dead or alive -- to the confines of the labs where they were created.Chased by a trained hunter and a ten-year-old mutant named Sniff, Jackson and Lacey flee across the USA, encountering other freed mutants, and learning to hide in plain sight. What they don't know might kill them, and their unwitting escape is the perfect dry kindling to spark a mutant/human war.
Publisher: Independently Published
ISBN: 9781092298797
Category :
Languages : en
Pages : 328
Book Description
Jackson and Lacey are mutants. They weren't born, they were created in a lab. The world outside doesn't know that they even exist, and corporations like Centratek want it that way. They want to keep their trained and specialized properties locked away to sell to the highest bidder.That is, until Jackson uses his illusion abilities to escape, and Lacey reaches out with her mind to find him. This sets a series of events in motion where Centratek must covertly do all they can to pluck Jackson and Lacey from the wild and return them -- dead or alive -- to the confines of the labs where they were created.Chased by a trained hunter and a ten-year-old mutant named Sniff, Jackson and Lacey flee across the USA, encountering other freed mutants, and learning to hide in plain sight. What they don't know might kill them, and their unwitting escape is the perfect dry kindling to spark a mutant/human war.
The Biology of Mammalian Spermatogonia
Author: Jon M. Oatley
Publisher: Springer
ISBN: 1493975056
Category : Science
Languages : en
Pages : 385
Book Description
This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area. Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals.
Publisher: Springer
ISBN: 1493975056
Category : Science
Languages : en
Pages : 385
Book Description
This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area. Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals.
Virus as Populations
Author: Esteban Domingo
Publisher: Academic Press
ISBN: 0128163321
Category : Science
Languages : en
Pages : 428
Book Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes
Publisher: Academic Press
ISBN: 0128163321
Category : Science
Languages : en
Pages : 428
Book Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes
Immunology and Evolution of Infectious Disease
Author: Steven A. Frank
Publisher: Princeton University Press
ISBN: 9780691095950
Category : Medical
Languages : en
Pages : 364
Book Description
Publisher Description
Publisher: Princeton University Press
ISBN: 9780691095950
Category : Medical
Languages : en
Pages : 364
Book Description
Publisher Description
Health Effects of Exposure to Low Levels of Ionizing Radiation
Author: National Research Council
Publisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436
Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Publisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436
Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Encyclopedia of Cancer
Author: Manfred Schwab
Publisher: Springer Science & Business Media
ISBN: 3540368477
Category : Medical
Languages : en
Pages : 3307
Book Description
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Publisher: Springer Science & Business Media
ISBN: 3540368477
Category : Medical
Languages : en
Pages : 3307
Book Description
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Cell Biology by the Numbers
Author: Ron Milo
Publisher: Garland Science
ISBN: 1317230698
Category : Science
Languages : en
Pages : 399
Book Description
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Publisher: Garland Science
ISBN: 1317230698
Category : Science
Languages : en
Pages : 399
Book Description
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Crumbling Genome
Author: Alexey S. Kondrashov
Publisher: John Wiley & Sons
ISBN: 1118952111
Category : Science
Languages : en
Pages : 309
Book Description
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.
Publisher: John Wiley & Sons
ISBN: 1118952111
Category : Science
Languages : en
Pages : 309
Book Description
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.
Plasmids
Author: Marcelo E. Tolmasky
Publisher: John Wiley & Sons
ISBN: 1555818986
Category : Science
Languages : en
Pages : 720
Book Description
Explore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of "omics" disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.
Publisher: John Wiley & Sons
ISBN: 1555818986
Category : Science
Languages : en
Pages : 720
Book Description
Explore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of "omics" disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.
Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
Author: OECD
Publisher: OECD Publishing
ISBN: 9264122818
Category :
Languages : en
Pages : 16
Book Description
This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The ...
Publisher: OECD Publishing
ISBN: 9264122818
Category :
Languages : en
Pages : 16
Book Description
This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The ...