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Author: Kenneth Chadwick
Publisher: CRC Press
ISBN: 1000733882
Category : Medical
Languages : en
Pages : 248
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Book Description
This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy
Author: Kenneth Chadwick
Publisher: CRC Press
ISBN: 1000733882
Category : Medical
Languages : en
Pages : 248
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Book Description
This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy
Author: K. H. Chadwick
Publisher: Springer Science & Business Media
ISBN: 3642815197
Category : Science
Languages : en
Pages : 394
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Book Description
In late 1971 we were involved in a study of the interaction of radiation with matter and were trying to use measurements of radiation fluorescence in biological molecules to indicate how radiation affected living cells. It soon became apparent that we were working in the dark; the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA molecule appeared to be the most likely target molecule we did not know which sort of events and which sort oflesions were the most important. We decided to alter our approach to see if we could find any consistent mathematical order in the radiobiological dose relationships. We found that cell survival curves could be very usefully described by a linear-quadratic dose relationship and very soon came to the somewhat premature but, as it turned out, most effective conclusion that the induction of DNA double strand breaks should be linear-quadratic. In deciding that the DNA double strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of the cell and were able to relate known properties of the DNA molecule to known radiobiological effects. On the other hand, we were restricted and brought, from an abstract two-hit lesion which could have any property one wished, down to earth, to a defined moleccular structure of nanometer dimensions and well-known functions and properties.
Author: Steve Forshier
Publisher: Cengage Learning
ISBN: 9780766813311
Category : Radiation
Languages : en
Pages : 0
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Book Description
Chapter Objectives, Lecture Outlines, Review of Key Terms, Review Questions, Web Resources, Answer Key
Author: Eric J. Hall
Publisher: Lippincott Williams & Wilkins
ISBN: 1451154186
Category : Medical
Languages : en
Pages : 908
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Book Description
In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.
Author: Hermann Dertinger
Publisher: Springer Science & Business Media
ISBN: 1468462474
Category : Science
Languages : en
Pages : 246
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Book Description
There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.
Author: Jürgen Kiefer
Publisher: Springer Science & Business Media
ISBN: 3642466567
Category : Science
Languages : en
Pages : 202
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Book Description
Radiation is the one agent among all environmental factors which may damage biological systems that is not only easily quantifiable but can also be measured with unsurpassed resolution. Its primary effects on atoms and molecules are well understood, and the secondary processes can be followed by sophisticated experimental techniques. The quantum nature of interactions and the importance of stochastic variations call for an exact mathematical description. This task is by no means simple, and presents a challenge both to the experimentalist and to the theoretician. It is hoped that a generally acceptable formalism will help to quantify radiation responses, both in radiation protection and radiation therapy, and make it possible to move from a purely empirical approach with all its fallacies to real understanding.
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 1118934695
Category : Medical
Languages : en
Pages : 2003
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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: Jeffrey I. Steinfeld
Publisher: Courier Corporation
ISBN: 0486137546
Category : Science
Languages : en
Pages : 514
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Book Description
This unified treatment introduces upper-level undergraduates and graduate students to the concepts and methods of modern molecular spectroscopy and their applications to quantum electronics, lasers, and related optical phenomena. Starting with a review of the prerequisite quantum mechanical background, the text examines atomic spectra and diatomic molecules, including the rotation and vibration of diatomic molecules and their electronic spectra. A discussion of rudimentary group theory advances to considerations of the rotational spectra of polyatomic molecules and their vibrational and electronic spectra; molecular beams, masers, and lasers; and a variety of forms of spectroscopy, including optical resonance spectroscopy, coherent transient spectroscopy, multiple-photon spectroscopy, and spectroscopy beyond molecular constants. The text concludes with a series of useful appendixes.
Author: Antone L. Brooks
Publisher:
ISBN: 9780874223545
Category : Science
Languages : en
Pages : 0
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Book Description
Chief Scientist Dr. Antone Brooks and his Low Dose Radiation Research Program team redefined the field, applying advances in instrumentation and molecular biology from the Human Genome Project and developing new technologies to examine cellular responses. Their findings were startling. At low doses, biological reactions are unique and often unrelated to those that occur at high doses. The influential linear-no-threshold model--which predicted that damage from acute exposures can be extrapolated linearly to low dose exposures--was flawed. Small doses of radiation can have an adaptive protective effect. "Hit theory," the idea that radiation only affected cells it directly traversed, yielded to "bystander theory," which hypothesizes that cells communicate with each other and a dose to one affects others surrounding it. Low Dose Radiation describes the program's development, the scientists who made it viable, and the fundamental results, highlighting lessons learned during its lifespan.
Author:
Publisher: Newnes
ISBN: 0444536337
Category : Science
Languages : en
Pages : 4052
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Book Description
Comprehensive Biomedical Physics, Ten Volume Set is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color
