Molecular Biology of the Cell PDF Download
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Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Tasuku Honjo
Publisher: Elsevier
ISBN: 0123984904
Category : Medical
Languages : en
Pages : 587
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Book Description
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. - Covers signaling mechanisms regulating B cell differentiation - Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab - Contains studies on B cell tumors from various stages of B lymphocytes - Offers an integrated view of all aspects of B cells to produce a normal immune response
Author: Marchalonis
Publisher: CRC Press
ISBN: 9780824777975
Category : Science
Languages : en
Pages : 452
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Book Description
Author: Robin E. Callard
Publisher: Academic Press
ISBN: 0080984320
Category : Medical
Languages : en
Pages : 283
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Book Description
Over the past five years the major importance of cytokines in the regulation of the immune system has become established. This book is the first to review the role of these factors in the control of growth of differentiation of B lymphocytes and thus represents an up-to-date and timely overview of the B-cell response.For the immunologist, there are detailed accounts of the physio-chemical properties of the relevant cytokines and their effect on B lymphocytes from the level of receptor signalling, through ontogeny, activation and proliferation to the expression of specific immunoglobulin isotypes. For the clinician, the involvement of cytokines in disease and normal immune response is discussed.
Author: Charles G. Craddock
Publisher:
ISBN:
Category : Cats
Languages : en
Pages : 24
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Book Description
Author: Constantin Bona
Publisher: Elsevier
ISBN: 0323159761
Category : Science
Languages : en
Pages : 226
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Book Description
Idiotypes and Lymphocytes reviews the progress made in the study of the idiotypes of lymphocytes, particularly the discovery that a vast spectrum of possible relationships between cells and antibodies and communications between various subsets of T- and B-lymphocytes exist within the immune system. The book explores autoanti-idiotype antibodies and the antigen-mimicking properties of anti-idiotype antibodies, along with the idiotypic determinants borne by the lymphocyte's receptor that serve as regulatory sites. Organized into seven chapters, this volume begins with an overview of idiotypy, from its discovery to the localization of idiotypic determinants in the variable regions. This book also explains how idiotypic specificity is associated with a particular antigenic specificity of the antibody molecule, the diversity of antibodies, and the regulation of the immune response. The next chapters introduce the reader to the ontogeny of idiotypic expression, touching on topics such as the development of B cells and sequential activation of V genes, along with the variability of idiotypic specificities during immune response. The book also explores the expression of idiotypes in B-lymphocytes and of idiotypic determinants of humoral antibodies in the antigenic receptors of T cells, as well as the mechanisms that allow anti-idiotype antibodies to regulate lymphocyte functions. The final chapter looks into the therapeutic implications of the immune network, with emphasis on the effects of anti-idiotypes antibodies in autoimmune diseases. This book is an essential reading for immunologists.
Author: Ian J. Forbes
Publisher: Springer Science & Business Media
ISBN: 1447114671
Category : Medical
Languages : en
Pages : 388
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Book Description
This book has been written from two points of view: firstly, from the viewpoint of those who are involved in the diagnosis and treatment of lymphoid malignancies, who must meet the challenge of integrating the new biological insights into their knowledge of these diseases; and secondly, from the viewpoint of those who are involved in basic biological approaches to malignancy and immunology, who wish to know more about the function of the lymphoid tissues and their malignant diseases. Neoplasia of lymphocytes is a focus for considering many of the most important biological advances impinging on cancer in the past two or three decades, because malignant lymphoproliferative diseases offer unequalled opportunities for studying many aspects of cancer. We probably know more about lymphocytes than other normal cells because of the ease with which they can be obtained. For the same reason we probably know more about malignant lymphocytes. One or other aspect of most of the momentous advances in biology of the past two or three decades has implications for lymphoid malignancies: hybridoma technology and the use of monoclonal antibodies, gene technology, the understanding of oncogenes and growth factors in the control of growth and differentiation, insights into causation of cancer by potent tumour promoters such as the phorbol esters and by viruses, and knowledge of the control of growth function of lymphocytes themselves. Conversely, many of the advances in understanding lym phocytic leukaemias and lymphomas have implications for other cancers.
Author: James Bumgardner Murphy
Publisher:
ISBN:
Category : Blood cells
Languages : en
Pages : 272
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Book Description
Author: R. Lowry Dobson
Publisher:
ISBN:
Category : Leucocytes
Languages : en
Pages : 18
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Book Description
Author: Gianni Marone
Publisher: Academic Press
ISBN: 0080535852
Category : Medical
Languages : en
Pages : 738
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Book Description
Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.
