The Logic of Biochemical Sequencing PDF Download
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Author: David Blackman
Publisher: CRC Press
ISBN: 9780849344978
Category : Medical
Languages : en
Pages : 200
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Book Description
The Logic of Biochemical Sequencing examines how to determine the primary structures of proteins and DNA and use them to stimulate the process of logical problem-solving. It concentrates on sequencing work and stresses the thought processes needed to make sense of what might otherwise be indecipherable data. The book also introduces "biocryptography," which serves as a basis for four short stories that use the results of sequence determinations to provide clues to higher order problems. Problems in the book range from elementary to difficult, and solutions to all problems are provided, many of them completely worked out. The book is an excellent supplementary text for students in a full-year biochemistry course, as well as for biochemists and molecular biologists.
Author: David Blackman
Publisher: CRC Press
ISBN: 9780849344978
Category : Medical
Languages : en
Pages : 200
Get Book Here
Book Description
The Logic of Biochemical Sequencing examines how to determine the primary structures of proteins and DNA and use them to stimulate the process of logical problem-solving. It concentrates on sequencing work and stresses the thought processes needed to make sense of what might otherwise be indecipherable data. The book also introduces "biocryptography," which serves as a basis for four short stories that use the results of sequence determinations to provide clues to higher order problems. Problems in the book range from elementary to difficult, and solutions to all problems are provided, many of them completely worked out. The book is an excellent supplementary text for students in a full-year biochemistry course, as well as for biochemists and molecular biologists.
Author: D. Blackman
Publisher: CRC Press
ISBN: 1351094068
Category : Medical
Languages : en
Pages : 135
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Book Description
The Logic of Biochemical Sequencing examines how to determine the primary structures of proteins and DNA and use them to stimulate the process of logical problem-solving. It concentrates on sequencing work and stresses the thought processes needed to make sense of what might otherwise be indecipherable data. The book also introduces "biocryptography," which serves as a basis for four short stories that use the results of sequence determinations to provide clues to higher order problems. Problems in the book range from elementary to difficult, and solutions to all problems are provided, many of them completely worked out. The book is an excellent supplementary text for students in a full-year biochemistry course, as well as for biochemists and molecular biologists.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Richard Durbin
Publisher: Cambridge University Press
ISBN: 113945739X
Category : Science
Languages : en
Pages : 372
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Book Description
Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038405
Category : Science
Languages : en
Pages : 128
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Book Description
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author:
Publisher:
ISBN:
Category : Amino acid sequence
Languages : en
Pages : 380
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Book Description
Author: Isabel Aguiló
Publisher: IOS Press
ISBN: 9781586033781
Category : Computers
Languages : en
Pages : 520
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Book Description
The main scope of this publication is to promote collaborations among research groups in the community and to interchange ideas, allowing researchers to get a quick overview of the state of the art. This volume looks at topics including robotics and computer vision and multiagent systems.
Author: Frances H. Arnold
Publisher: Springer Science & Business Media
ISBN: 1592593968
Category : Science
Languages : en
Pages : 381
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Book Description
Directed evolution comprises two distinct steps that are typically applied in an iterative fashion: (1) generating molecular diversity and (2) finding among the ensemble of mutant sequences those proteins that perform the desired fu- tion according to the specified criteria. In many ways, the second step is the most challenging. No matter how cleverly designed or diverse the starting library, without an effective screening strategy the ability to isolate useful clones is severely diminished. The best screens are (1) high throughput, to increase the likelihood that useful clones will be found; (2) sufficiently sen- tive (i. e. , good signal to noise) to allow the isolation of lower activity clones early in evolution; (3) sufficiently reproducible to allow one to find small improvements; (4) robust, which means that the signal afforded by active clones is not dependent on difficult-to-control environmental variables; and, most importantly, (5) sensitive to the desired function. Regarding this last point, almost anyone who has attempted a directed evolution experiment has learned firsthand the truth of the dictum “you get what you screen for. ” The protocols in Directed Enzyme Evolution describe a series of detailed p- cedures of proven utility for directed evolution purposes. The volume begins with several selection strategies for enzyme evolution and continues with assay methods that can be used to screen enzyme libraries. Genetic selections offer the advantage that functional proteins can be isolated from very large libraries s- ply by growing a population of cells under selective conditions.
Author:
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 748
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Book Description
Vols. 36- include Proceedings of the Biochemical Society.
Author: Jerzy Kulski
Publisher: BoD – Books on Demand
ISBN: 9535122401
Category : Medical
Languages : en
Pages : 466
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Book Description
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
