Author: Kenro Kusumi
Publisher: Springer Science & Business Media
ISBN: 1441914064
Category : Medical
Languages : en
Pages : 227
Book Description
Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.
The Genetics and Development of Scoliosis
Author: Kenro Kusumi
Publisher: Springer Science & Business Media
ISBN: 1441914064
Category : Medical
Languages : en
Pages : 227
Book Description
Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.
Publisher: Springer Science & Business Media
ISBN: 1441914064
Category : Medical
Languages : en
Pages : 227
Book Description
Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.
Pathogenesis of Idiopathic Scoliosis
Author: Masafumi Machida
Publisher: Springer
ISBN: 4431565418
Category : Medical
Languages : en
Pages : 193
Book Description
This book provides comprehensive coverage of current topics in idiopathic scoliosis (IS). A three-dimensional deformity of the spine, the condition is characterized by lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. Although the clinical manifestations of scoliosis have been well documented, its cause and pathogenesis have not yet been determined. Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics. Results of these studies have brought about a new perception of IS epiphenomena, but the main cause of IS remains unknown. Recently, several investigators have produced new hypotheses regarding the cause of IS using the developing techniques of genetics, biochemistry, and neurology. This book is a review of the various causative factors thus far proposed for IS and an introduction to the directions in which research is heading to determine the primary cause of IS.
Publisher: Springer
ISBN: 4431565418
Category : Medical
Languages : en
Pages : 193
Book Description
This book provides comprehensive coverage of current topics in idiopathic scoliosis (IS). A three-dimensional deformity of the spine, the condition is characterized by lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. Although the clinical manifestations of scoliosis have been well documented, its cause and pathogenesis have not yet been determined. Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics. Results of these studies have brought about a new perception of IS epiphenomena, but the main cause of IS remains unknown. Recently, several investigators have produced new hypotheses regarding the cause of IS using the developing techniques of genetics, biochemistry, and neurology. This book is a review of the various causative factors thus far proposed for IS and an introduction to the directions in which research is heading to determine the primary cause of IS.
Adolescent Idiopathic Scoliosis
Author: Peter O. Newton
Publisher: AAOS
ISBN: 9780892033331
Category : Scoliosis
Languages : en
Pages : 0
Book Description
Covers the anatomy, etiology, and natural history of scoliosis - from patient evaluation and an algorithm for treatment to pulmonary function after surgical treatment and the use of instruments to evaluate surgical treatment. This new monograph focuses on the most common form of scoliosis occurring otherwise normal adolescents, affecting spinal alignment, growth, and function.
Publisher: AAOS
ISBN: 9780892033331
Category : Scoliosis
Languages : en
Pages : 0
Book Description
Covers the anatomy, etiology, and natural history of scoliosis - from patient evaluation and an algorithm for treatment to pulmonary function after surgical treatment and the use of instruments to evaluate surgical treatment. This new monograph focuses on the most common form of scoliosis occurring otherwise normal adolescents, affecting spinal alignment, growth, and function.
Disordered Vertebral and Rib Morphology in Pudgy Mice
Author: Frederic Shapiro
Publisher: Springer
ISBN: 9783319431499
Category : Medical
Languages : en
Pages : 0
Book Description
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections which allow for high level resolution not only of vertebrae, intervertebral discs, and ribs but also of associated spinal cord, nerve roots and ganglia. In addition an overview of embryo and neonatal development in mouse, chick and human vertebrae is provided to better assess how and where deviant pathoanatomy occurs. The book discusses the possible variables involved in creating final deformity beyond the gene abnormality itself.
Publisher: Springer
ISBN: 9783319431499
Category : Medical
Languages : en
Pages : 0
Book Description
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections which allow for high level resolution not only of vertebrae, intervertebral discs, and ribs but also of associated spinal cord, nerve roots and ganglia. In addition an overview of embryo and neonatal development in mouse, chick and human vertebrae is provided to better assess how and where deviant pathoanatomy occurs. The book discusses the possible variables involved in creating final deformity beyond the gene abnormality itself.
Congenital Scoliosis
Author: Elio Ascani
Publisher:
ISBN: 9783211820810
Category : Scoliosis
Languages : en
Pages : 170
Book Description
The third volume of Progress in Spinal Pathology gathers a selection of papers presented at the 7th National Meeting of the Italian Scoliosis Research Group on Congenital Scoliosis. Up until 20 years ago congenital scoliosis was considered to be a practically benign disease characterized by a slight progression of spinal deformity and its prognosis was consequently good. This statement has recently turned out to be too optimistic. Deeper studies on spinal pathology have proved the existence of highly progressive forms of congenital scoliosis often associated with other diseases affecting the urinary and cardiac systems and above all the spinal cord. As a result a careful evaluation of the patient is necessary before any type of surgical treatment may be initiated, in order to reduce the risk of irreversible lesions to the spinal cord to a minimum. This volume encompasses all clinical and diagnostic aspects of the subject including the latest achievements and techniques of treatment. Furthermore it is completed by eminent studies on subjects of great interest such as imperfect osteogenesis, cervical and cranial abnormalities in von Recklinghausen's disease, experimental comparative analysis of different types of instrumentation used in the surgical treatment of vertebral fractures, rib resection following vertebral arthrodesis for cases of thoracic idiopathic scoliosis, and anesthesia in vertebral surgery for spinal muscle atrophy.
Publisher:
ISBN: 9783211820810
Category : Scoliosis
Languages : en
Pages : 170
Book Description
The third volume of Progress in Spinal Pathology gathers a selection of papers presented at the 7th National Meeting of the Italian Scoliosis Research Group on Congenital Scoliosis. Up until 20 years ago congenital scoliosis was considered to be a practically benign disease characterized by a slight progression of spinal deformity and its prognosis was consequently good. This statement has recently turned out to be too optimistic. Deeper studies on spinal pathology have proved the existence of highly progressive forms of congenital scoliosis often associated with other diseases affecting the urinary and cardiac systems and above all the spinal cord. As a result a careful evaluation of the patient is necessary before any type of surgical treatment may be initiated, in order to reduce the risk of irreversible lesions to the spinal cord to a minimum. This volume encompasses all clinical and diagnostic aspects of the subject including the latest achievements and techniques of treatment. Furthermore it is completed by eminent studies on subjects of great interest such as imperfect osteogenesis, cervical and cranial abnormalities in von Recklinghausen's disease, experimental comparative analysis of different types of instrumentation used in the surgical treatment of vertebral fractures, rib resection following vertebral arthrodesis for cases of thoracic idiopathic scoliosis, and anesthesia in vertebral surgery for spinal muscle atrophy.
Exploring Adult Scoliosis
Author: Tony Nalda
Publisher:
ISBN: 9780578984513
Category :
Languages : en
Pages : 214
Book Description
Being an adult with scoliosis can be lonely, painful, and frustrating. I know this because I have worked with adults from all over the world who came to me with similar complaints. In this book, we explore what adult scoliosis is, how it differs from adolescent scoliosis, treatment options available for adults with scoliosis, how these treatment options address pain, and the pros and cons of the different scoliosis treatment opportunities.
Publisher:
ISBN: 9780578984513
Category :
Languages : en
Pages : 214
Book Description
Being an adult with scoliosis can be lonely, painful, and frustrating. I know this because I have worked with adults from all over the world who came to me with similar complaints. In this book, we explore what adult scoliosis is, how it differs from adolescent scoliosis, treatment options available for adults with scoliosis, how these treatment options address pain, and the pros and cons of the different scoliosis treatment opportunities.
Scoliosis Hope
Author: Dr Tony Nalda
Publisher:
ISBN: 9780578498362
Category :
Languages : en
Pages : 216
Book Description
Traditional scoliosis treatments prescribe years of "watching and waiting" instead of decisive action. The chiropractic-centered approach to treating scoliosis is proactive, effective and hopeful. Surgery can often times be avoided. Patients can live rich, full, and active lives. This book shows you how it is all possible.
Publisher:
ISBN: 9780578498362
Category :
Languages : en
Pages : 216
Book Description
Traditional scoliosis treatments prescribe years of "watching and waiting" instead of decisive action. The chiropractic-centered approach to treating scoliosis is proactive, effective and hopeful. Surgery can often times be avoided. Patients can live rich, full, and active lives. This book shows you how it is all possible.
The Conservative Scoliosis Treatment
Author: Society on Scoliosis Orthopaedic and Rehabilitation Treatment
Publisher: IOS Press
ISBN: 1586038427
Category : Medical
Languages : en
Pages : 440
Book Description
This is the first of a series of Instructional Course Lectures (ICL) books of the International Society On Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT). In the contents of this book the reader can find the SOSORT statutes and become familiar with the aims of the creation of this society. This will hopefully be the initiation of a series of books on conservative scoliosis treatment and a valuable library for SOSORT. The philosophy of the commencement of such ICL book series is the achievement of an ultimate aim, the improvement of early detection and non operative treatment of the patient care pathway for scoliosis. For this endeavor, a number of eminent clinicians and scientists around the world, who are devoted and high-quality students of scoliosis, are involved with and contributing to their fabulous work. There is no doubt that this book is not able to cover every aspect of the issue. However, the future volumes of this series of books will continuously complete the latest relevant knowledge. In this volume there are chapters reporting on various aspects of the current state of the following topics: IS aetiology, recent trends on scoliosis research, genetics, prevention - school screening, various methods of physiotherapy, various types of braces, the inclusion criteria for conservative treatment, together with the SOSORT guidelines for conservative treatment, clinical evaluation and classification, study of the surface after brace application and outcomes for each brace.
Publisher: IOS Press
ISBN: 1586038427
Category : Medical
Languages : en
Pages : 440
Book Description
This is the first of a series of Instructional Course Lectures (ICL) books of the International Society On Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT). In the contents of this book the reader can find the SOSORT statutes and become familiar with the aims of the creation of this society. This will hopefully be the initiation of a series of books on conservative scoliosis treatment and a valuable library for SOSORT. The philosophy of the commencement of such ICL book series is the achievement of an ultimate aim, the improvement of early detection and non operative treatment of the patient care pathway for scoliosis. For this endeavor, a number of eminent clinicians and scientists around the world, who are devoted and high-quality students of scoliosis, are involved with and contributing to their fabulous work. There is no doubt that this book is not able to cover every aspect of the issue. However, the future volumes of this series of books will continuously complete the latest relevant knowledge. In this volume there are chapters reporting on various aspects of the current state of the following topics: IS aetiology, recent trends on scoliosis research, genetics, prevention - school screening, various methods of physiotherapy, various types of braces, the inclusion criteria for conservative treatment, together with the SOSORT guidelines for conservative treatment, clinical evaluation and classification, study of the surface after brace application and outcomes for each brace.
The Genetics and Development of Scoliosis
Author: Kenro Kusumi
Publisher: Springer
ISBN: 3319901494
Category : Medical
Languages : en
Pages : 204
Book Description
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Publisher: Springer
ISBN: 3319901494
Category : Medical
Languages : en
Pages : 204
Book Description
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Early Onset Scoliosis
Author: Colin Nnadi
Publisher: Thieme
ISBN: 3131726717
Category : Medical
Languages : en
Pages : 726
Book Description
A comprehensive guide to modern treatment in a complex and evolving specialty FIVE STARS from Doody's Star Ratings™ Covering the spectrum of spinal deformity that occurs between birth and 10 years, early onset scoliosis (EOS) is an evolving specialty that faces unique challenges, especially in controlling the progression of the condition while allowing the growth of the developing spine, lungs and thorax. This important book was inspired by the inaugural early onset scoliosis meeting of spine surgeons and other medical professionals in Christ Church, Oxford, UK, in September 2011. It provides a complete picture of the field today, with topics ranging from spinal development and genetics to advances in medical management to breakthrough surgical techniques that offer promising new options for young patients. Special Features Provides practical, evidence-based solutions to managing the full range of congenital, idiopathic, neuromuscular and syndromic conditions that present in early onset scoliosis Describes pioneering surgical procedures, such as non-invasive, magnetically controlled growing rod systems that reduce the number of repetitive surgeries and hospitalizations Explores such complex topics as surgical strategies for sitting comfort and features of optimal heelchair seating Details treatments and outcome measures in diverse, multi-system disorders, such as early onset neuromuscular scoliosis Highlights perioperative care and the vital role of physiotherapy in children with EOS Introduces an EOS questionnaire that establishes validated, patient-reported data for outcome assessment Recognizing the importance of the multidisciplinary team approach in effective management, Early Onset Scoliosis offers the valuable international perspective of many leaders in the field. It is essential for orthopedic and pediatric surgeons, residents and trainees, who will use the book to develop a clear understanding of what EOS is, how it is best treated, and the principles that underlie effective clinical decision-making in these complex cases.
Publisher: Thieme
ISBN: 3131726717
Category : Medical
Languages : en
Pages : 726
Book Description
A comprehensive guide to modern treatment in a complex and evolving specialty FIVE STARS from Doody's Star Ratings™ Covering the spectrum of spinal deformity that occurs between birth and 10 years, early onset scoliosis (EOS) is an evolving specialty that faces unique challenges, especially in controlling the progression of the condition while allowing the growth of the developing spine, lungs and thorax. This important book was inspired by the inaugural early onset scoliosis meeting of spine surgeons and other medical professionals in Christ Church, Oxford, UK, in September 2011. It provides a complete picture of the field today, with topics ranging from spinal development and genetics to advances in medical management to breakthrough surgical techniques that offer promising new options for young patients. Special Features Provides practical, evidence-based solutions to managing the full range of congenital, idiopathic, neuromuscular and syndromic conditions that present in early onset scoliosis Describes pioneering surgical procedures, such as non-invasive, magnetically controlled growing rod systems that reduce the number of repetitive surgeries and hospitalizations Explores such complex topics as surgical strategies for sitting comfort and features of optimal heelchair seating Details treatments and outcome measures in diverse, multi-system disorders, such as early onset neuromuscular scoliosis Highlights perioperative care and the vital role of physiotherapy in children with EOS Introduces an EOS questionnaire that establishes validated, patient-reported data for outcome assessment Recognizing the importance of the multidisciplinary team approach in effective management, Early Onset Scoliosis offers the valuable international perspective of many leaders in the field. It is essential for orthopedic and pediatric surgeons, residents and trainees, who will use the book to develop a clear understanding of what EOS is, how it is best treated, and the principles that underlie effective clinical decision-making in these complex cases.