Author:
Publisher: Academic Press
ISBN: 012374105X
Category : Science
Languages : en
Pages : 1633
Book Description
The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists
Encyclopedia of Movement Disorders
Author:
Publisher: Academic Press
ISBN: 012374105X
Category : Science
Languages : en
Pages : 1633
Book Description
The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists
Publisher: Academic Press
ISBN: 012374105X
Category : Science
Languages : en
Pages : 1633
Book Description
The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists
The Dopamine Receptors
Author: Kim Neve
Publisher: Springer Science & Business Media
ISBN: 147572635X
Category : Medical
Languages : en
Pages : 555
Book Description
Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and newcomers to the dopamine receptor field, while at the same time providing up-to-date summaries of the most active areas of research. It is difficult these days to write about receptors without addressing the issue of receptor nomenclature. For dopamine receptors, valid arguments can be made for a system in which the subtypes are classified as belonging to the Dl or D2 classes, with letters assigned in the order of cloning (D A, D , D A, 1 18 2 D , Dc). We decided, however, that common usage counts for something, and 28 2 chose to use D , D , and D for the D2-like receptors because these names are 2 3 4 nearly unanimously used in the literature.
Publisher: Springer Science & Business Media
ISBN: 147572635X
Category : Medical
Languages : en
Pages : 555
Book Description
Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and newcomers to the dopamine receptor field, while at the same time providing up-to-date summaries of the most active areas of research. It is difficult these days to write about receptors without addressing the issue of receptor nomenclature. For dopamine receptors, valid arguments can be made for a system in which the subtypes are classified as belonging to the Dl or D2 classes, with letters assigned in the order of cloning (D A, D , D A, 1 18 2 D , Dc). We decided, however, that common usage counts for something, and 28 2 chose to use D , D , and D for the D2-like receptors because these names are 2 3 4 nearly unanimously used in the literature.
The Dopamine Receptors
Author: Kim Neve
Publisher: Springer Science & Business Media
ISBN: 1603273336
Category : Medical
Languages : en
Pages : 650
Book Description
As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.
Publisher: Springer Science & Business Media
ISBN: 1603273336
Category : Medical
Languages : en
Pages : 650
Book Description
As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.
Molecular Biology of G-protein-coupled Receptors
Author: Mark R. Brann
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 352
Book Description
LESLIE L. IVERSEN The present series of volumes is well timed, as the impact of molecular genetics on pharmacology has been profound, and a comprehensive review of the rapid advances of the past decade is much needed. Since the pioneering work of Dale, Ariens, and others in the early years of this century, much of pharmacology has been founded on the concept of receptors. To begin with, the receptor was conceived of as a "black box," which recognized and transduced the biological effects of neurotransmit ters, hormones, or other biological messengers-and which could also represent a target for man-made drugs. It is only in the last two decades that "molecular pharmacology" has blossomed, first with the advent of radioligand binding techniques and second messenger studies which greatly facilitated the biochemical study of drug-receptor interactions, and latterly with increasing knowledge of the molecular architecture of the receptor proteins themselves. This started with the traditional biochemical approach of isolating and purifying the receptor molecules. This proved to be a task of immense technical difficulty because of the low density of receptors in most biological source tissues, although there were some notable successes, e. g. , the purification of the nicotinic acetylcholine receptor from the electric organ of Torpedo. It was the ap plication of molecular genetics technology during the 1980s, however, which really accelerated progress in this field.
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 352
Book Description
LESLIE L. IVERSEN The present series of volumes is well timed, as the impact of molecular genetics on pharmacology has been profound, and a comprehensive review of the rapid advances of the past decade is much needed. Since the pioneering work of Dale, Ariens, and others in the early years of this century, much of pharmacology has been founded on the concept of receptors. To begin with, the receptor was conceived of as a "black box," which recognized and transduced the biological effects of neurotransmit ters, hormones, or other biological messengers-and which could also represent a target for man-made drugs. It is only in the last two decades that "molecular pharmacology" has blossomed, first with the advent of radioligand binding techniques and second messenger studies which greatly facilitated the biochemical study of drug-receptor interactions, and latterly with increasing knowledge of the molecular architecture of the receptor proteins themselves. This started with the traditional biochemical approach of isolating and purifying the receptor molecules. This proved to be a task of immense technical difficulty because of the low density of receptors in most biological source tissues, although there were some notable successes, e. g. , the purification of the nicotinic acetylcholine receptor from the electric organ of Torpedo. It was the ap plication of molecular genetics technology during the 1980s, however, which really accelerated progress in this field.
Dopamine Nation
Author: Dr. Anna Lembke
Publisher: Penguin
ISBN: 1524746746
Category : Psychology
Languages : en
Pages : 305
Book Description
INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER “Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.
Publisher: Penguin
ISBN: 1524746746
Category : Psychology
Languages : en
Pages : 305
Book Description
INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER “Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.
Sax's Dangerous Properties of Industrial Materials
Author: Richard J. Lewis (Sr.)
Publisher: Van Nostrand Reinhold Company
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 894
Book Description
Publisher: Van Nostrand Reinhold Company
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 894
Book Description
The Molecule of More
Author: Daniel Z. Lieberman
Publisher: BenBella Books
ISBN: 1946885290
Category : Psychology
Languages : en
Pages : 240
Book Description
Why are we obsessed with the things we want only to be bored when we get them? Why is addiction perfectly logical to an addict? Why does love change so quickly from passion to indifference? Why are some people die-hard liberals and others hardcore conservatives? Why are we always hopeful for solutions even in the darkest times—and so good at figuring them out? The answer is found in a single chemical in your brain: dopamine. Dopamine ensured the survival of early man. Thousands of years later, it is the source of our most basic behaviors and cultural ideas—and progress itself. Dopamine is the chemical of desire that always asks for more—more stuff, more stimulation, and more surprises. In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it's why we gamble and squander. From dopamine's point of view, it's not the having that matters. It's getting something—anything—that's new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion—and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.
Publisher: BenBella Books
ISBN: 1946885290
Category : Psychology
Languages : en
Pages : 240
Book Description
Why are we obsessed with the things we want only to be bored when we get them? Why is addiction perfectly logical to an addict? Why does love change so quickly from passion to indifference? Why are some people die-hard liberals and others hardcore conservatives? Why are we always hopeful for solutions even in the darkest times—and so good at figuring them out? The answer is found in a single chemical in your brain: dopamine. Dopamine ensured the survival of early man. Thousands of years later, it is the source of our most basic behaviors and cultural ideas—and progress itself. Dopamine is the chemical of desire that always asks for more—more stuff, more stimulation, and more surprises. In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it's why we gamble and squander. From dopamine's point of view, it's not the having that matters. It's getting something—anything—that's new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion—and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.
Sax's Dangerous Properties of Industrial Materials, 3 Volume Set
Author: Richard J. Lewis (Sr.)
Publisher: Wiley-Interscience
ISBN:
Category : Science
Languages : en
Pages : 1000
Book Description
Since its inception in the early 1950s, this work has become the "bible" for those who need to evaluate the hazard of substances used in commerce. It is the only reference that combines, for so many substances, data on toxicological, fire, reactivity, explosive potential, and regulatory information. Highly acclaimed in the professional journals, it was reviewed as "an indispensable reference guide for professionals responsible for managing industrial safety and occupational exposure...an extraordinary work," and as "a monumental work...Efforts like this are the things of what history is made," among other reviews.
Publisher: Wiley-Interscience
ISBN:
Category : Science
Languages : en
Pages : 1000
Book Description
Since its inception in the early 1950s, this work has become the "bible" for those who need to evaluate the hazard of substances used in commerce. It is the only reference that combines, for so many substances, data on toxicological, fire, reactivity, explosive potential, and regulatory information. Highly acclaimed in the professional journals, it was reviewed as "an indispensable reference guide for professionals responsible for managing industrial safety and occupational exposure...an extraordinary work," and as "a monumental work...Efforts like this are the things of what history is made," among other reviews.
Presynaptic Receptors and Neuronal Transporters
Author: S.Z. Langer
Publisher: Elsevier
ISBN: 1483278220
Category : Science
Languages : en
Pages : 373
Book Description
Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.
Publisher: Elsevier
ISBN: 1483278220
Category : Science
Languages : en
Pages : 373
Book Description
Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.
Anesthesiology Core Review
Author: Brian Freeman
Publisher: McGraw Hill Professional
ISBN: 0071821384
Category : Medical
Languages : en
Pages : 588
Book Description
A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination.
Publisher: McGraw Hill Professional
ISBN: 0071821384
Category : Medical
Languages : en
Pages : 588
Book Description
A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination.