The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A

The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A PDF Author: Jeffrey L. Henry
Publisher:
ISBN:
Category :
Languages : en
Pages : 338

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The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A

The Design, Synthesis, and Biological Evaluation of Conformational Analogues of Dactylolide, Zampanolide and GEX1A PDF Author: Jeffrey L. Henry
Publisher:
ISBN:
Category :
Languages : en
Pages : 338

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Book Description


Total Synthesis and Biological Evaluation of (-)-zampanolide, (-)-dactylolide and of Analogs Thereof

Total Synthesis and Biological Evaluation of (-)-zampanolide, (-)-dactylolide and of Analogs Thereof PDF Author: Didier Zurwerra
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Applied Cross-Coupling Reactions

Applied Cross-Coupling Reactions PDF Author: Yasushi Nishihara
Publisher: Springer Science & Business Media
ISBN: 3642323685
Category : Science
Languages : en
Pages : 247

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Book Description
“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.

Privileged Scaffolds in Medicinal Chemistry

Privileged Scaffolds in Medicinal Chemistry PDF Author: Stefan Bräse
Publisher: Royal Society of Chemistry
ISBN: 1782620303
Category : Medical
Languages : en
Pages : 486

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Book Description
This book addresses the various classes of privileged scaffolds and covers the history of their discovery and use.

The Fables of Jesus in the Gospel of Luke

The Fables of Jesus in the Gospel of Luke PDF Author: Justin David Strong
Publisher: Brill Schoningh
ISBN: 9783506760654
Category :
Languages : en
Pages : 629

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Justice as a Virtue

Justice as a Virtue PDF Author: Porter
Publisher: Wm. B. Eerdmans Publishing
ISBN: 0802873251
Category : Law
Languages : en
Pages : 300

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Book Description
"Aquinas," says Jean Porter, "gets justice right." In this book she shows that Aquinas offers us a cogent and illuminating account of justice as a personal virtue rather than a virtue of social institutions. For Aquinas, justice is more about interpersonal morality than civic or social obligations, and Porter masterfully draws out the contemporary significance of Aquinas's perspective. - back of book.

Advances in Cross-Coupling Reactions

Advances in Cross-Coupling Reactions PDF Author: José Pérez Sestelo
Publisher: MDPI
ISBN: 3039435671
Category : Science
Languages : en
Pages : 234

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Book Description
In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki–Miyaura and Buchwald–Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C–H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki–Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered.

N-Heterocycles

N-Heterocycles PDF Author: Keshav Lalit Ameta
Publisher: Springer Nature
ISBN: 981190832X
Category : Science
Languages : en
Pages : 465

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Book Description
This book presents an overview of the recent advancements for the synthesis of small- and medium-sized azaheterocycles, including pyrroles, indoles, pyrimidines, pyridines, pyrrolidines, imidazoles, pyrazoles, pyrazolines, lactams, and 1,2,3-triazoles, which are significant scaffolds for compounds with pharmaceutical uses. The book also discusses various properties and performance attributes of azaheterocycles including their bioactivity and synthetic strategies. Given the contents, the book will be a valuable reference for students, researchers, and professionals interested in organic synthesis and medicinal chemistry.