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Author: Helen Stringer
Publisher: Createspace Independent Publishing Platform
ISBN: 9781480195448
Category : Children's stories
Languages : en
Pages : 0
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Book Description
Belladonna Johnson and Steve discover a girl who has been waiting two thousand years for someone to rescue her, and they find themselves involved with Old Magic and people and spirits unknown to even the mighty Queen of the Abyss. This time they are on their own, and to make things even more complicated, it's Halloween, the one time of year when ghosts can go wherever they want.
Author: Helen Stringer
Publisher: Createspace Independent Publishing Platform
ISBN: 9781480195448
Category : Children's stories
Languages : en
Pages : 0
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Book Description
Belladonna Johnson and Steve discover a girl who has been waiting two thousand years for someone to rescue her, and they find themselves involved with Old Magic and people and spirits unknown to even the mighty Queen of the Abyss. This time they are on their own, and to make things even more complicated, it's Halloween, the one time of year when ghosts can go wherever they want.
Author: Azalea Ellis
Publisher: Seladore Publishing
ISBN:
Category : Fiction
Languages : en
Pages : 716
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Book Description
To study magic at the University, Siobhan sacrificed her name. She sacrificed her body, and her past. Magically disguised as a boy named Sebastien, she is learning wondrous secrets of the thaumaturgic sciences. As Sebastien, she mingles with the young nobles who will one day rule their country. But danger is closer than ever, and she cannot escape her past. The coppers investigating the theft of Siobhan's priceless transformation artifact have given her a new name. The Raven Queen. As Siobhan does favors for the gang that loaned her the University tuition, the Raven Queen's mystique only grows. And keeps growing... ...Snowballing out of control until Siobhan's other identity takes on a life of its own, a fear-inducing bogeyman well beyond the truth of her real capabilities. With the whole city out to get her and trouble hounding both sides of her double life, how will Siobhan ever survive to become the world's most powerful sorcerer?
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Ryan Cahill
Publisher:
ISBN: 9781838381806
Category :
Languages : en
Pages : 542
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Book Description
Of Blood and Fire is a classic Epic Fantasy adventure. It takes all the familiar fantasy tropes - elves, dwarves, giants, and dragons - and adds a fresh, contemporary twist.
Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 0470249021
Category : Medical
Languages : en
Pages : 1352
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Book Description
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
Author: Robin Wasserman
Publisher: Ember
ISBN: 0375872779
Category : Fiction
Languages : en
Pages : 466
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Book Description
While working on a project translating letters from sixteenth-century Prague, high school senior Nora Kane discovers her best friend murdered with her boyfriend the apparent killer and is caught up in a dangerous web of secret societies and shadowy conspirators, all searching for a mysterious ancient device purported to allow direct communication with God.
Author: Sarah J. Maas
Publisher: Bloomsbury Publishing USA
ISBN: 1619630664
Category : Fiction
Languages : en
Pages : 596
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Book Description
The heir of ash and fire bows to no one. A new threat rises in the third book in the #1 bestselling Throne of Glass series by Sarah J. Maas. Celaena Sardothien has survived deadly contests and shattering heartbreak, but now she must travel to a new land to confront her darkest truth. That truth could change her life-and her future-forever. Meanwhile, monstrous forces are gathering on the horizon, intent on enslaving her world. To defeat them, Celaena will need the strength not only to fight the evil that is about to be unleashed but also to harness her inner demons. If she is to win this battle, she must find the courage to face her destiny-and burn brighter than ever before. The third book in the #1 New York Times bestselling Throne of Glass series continues Celaena's epic journey from woman to warrior.
Author: William M. Pardridge
Publisher: Cambridge University Press
ISBN: 9780521581240
Category : Medical
Languages : en
Pages : 504
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Book Description
The blood-brain barrier serves to protect the brain from toxic substances whilst simultaneously allowing access to essential nutrients and chemical signals. At the interface between brain and body, knowledge of the blood-brain barrier forms an essential component in the complete understanding of a large proportion of medical disciplines. Nevertheless, it seems that ignorance of both the biology of this important membrane and the methodology suitable for its investigation still remains an impediment to progress in many fields, including, for example, the development of new and efficacious neuropharmaceuticals, cerebrovascular disease, Alzheimer's disease, cerebral AIDS and brain tumours. This introduction for both researchers and clinicians across the medical sciences is intended to aid both those beginning work directly in this area and those wishing simply to be better informed when interpreting information where the blood-brain barrier may be involved. Advances in both methodology and biology are detailed in 50 chapters from international authorities.
Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1842145363
Category : Medical
Languages : en
Pages : 2186
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Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Author: A. E. Lowan
Publisher:
ISBN: 9781732316409
Category : Fiction
Languages : en
Pages : 400
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Book Description
Winter Mulcahy is a wizard physician who has found herself holding the political reins of a city falling apart around her ears. She is exhausted, in over her head, and has turned to stimulants just to get by. Two sidhe lords come into her life telling her that a faerie prince has been kidnapped and they need her help to get him back.
