Cancer Immunology and Immunotherapy

Cancer Immunology and Immunotherapy PDF Author: Mansoor M. Amiji
Publisher: Academic Press
ISBN: 012823637X
Category : Medical
Languages : en
Pages : 550

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Book Description
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Comprehensive treaty covering all aspects of immuno-oncology (IO) - Novel strategies for delivery of IO therapeutics and vaccines - Forecasting on the future of nanotechnology and drug delivery for IO

Here Be Sexist Vampires

Here Be Sexist Vampires PDF Author: Suzanne Wright
Publisher: Createspace Independent Pub
ISBN: 9781481978064
Category : Fiction
Languages : en
Pages : 266

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Book Description
Sam Parker is a vampire with a gift so strong and substantial that she is invited to partake in a test for a place in the Grand High Master Vampire's private army. She finds that not only has the army never included a woman, but it has never included a Sventé vampire; a breed that is regarded by the super strong Pagori breed and the hypnotically beautiful Keja breed to be too tame and human-like. Most refuse to take her seriously, especially a Pagori commander named Jared who she craves in spite of herself. The Grand High Master, however, sees her potential and offers her the position of Jared's co-commander to help train the newest squad in time for the impending attack on his home. Sam has to demonstrate to Jared and the squad of chauvinists why it is incredibly foolish to underestimate a wilful, temperamental, borderline-homicidal Sventé female. Warning: This novel contains an iron-willed female vampire with an energy whip, a sexist male vampire who is determined to have her, explicit vampy sex, and a romance story with real bite.

Healing the Shame that Binds You

Healing the Shame that Binds You PDF Author: John Bradshaw
Publisher: Health Communications, Inc.
ISBN: 0757303234
Category : Psychology
Languages : en
Pages : 338

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Book Description
This classic book, written 17 years ago but still selling more than 13,000 copies every year, has been completely updated and expanded by the author. "I used to drink," writes John Bradshaw,"to solve the problems caused by drinking. The more I drank to relieve my shame-based loneliness and hurt, the more I felt ashamed." Shame is the motivator behind our toxic behaviors: the compulsion, co-dependency, addiction and drive to superachieve that breaks down the family and destroys personal lives. This book has helped millions identify their personal shame, understand the underlying reasons for it, address these root causes and release themselves from the shame that binds them to their past failures.

Destiny Binds

Destiny Binds PDF Author: Tammy Blackwell
Publisher: Createspace Independent Publishing Platform
ISBN: 9781460918685
Category : Kentucky
Languages : en
Pages : 0

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Book Description
After a tragic accident leaves her battered, heartbroken, and alone, Scout Donovan would rather hide in dreams than face reality. But things are changing quickly in Scout's life. Soon she's pulled back into the world of the Shifters and Seers, with her best friend's fate depending on Scout's ability to protect her. Can Scout pull it together in time to save Talley, or is the past too much to overcome?

Magic Bites

Magic Bites PDF Author: Ilona Andrews
Publisher: Penguin
ISBN: 1101619902
Category : Fiction
Languages : en
Pages : 386

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Book Description
#1 New York Times bestselling author Ilona Andrews invites you to experience the first novel in the “intriguing world” (Locus) of Kate Daniels with this special edition of Magic Bites... Kate Daniels is a down-on-her-luck mercenary who makes her living cleaning up magical problems. But when Kate’s guardian is murdered, her quest for justice draws her into a power struggle between two strong factions within Atlanta’s magic circles. Pressured by both sides to find the killer, Kate realizes she’s way out of her league—but she wouldn’t want it any other way... This special edition includes in-depth information about the world of Kate Daniels, with descriptions of its characters and factions. Explore Kate’s Atlanta like never before with answers to FAQ and a quiz to find your place there. And don’t miss the prequel story “A Questionable Client,” as well as scenes of events in Magic Bites from Curran’s point of view.

Blood That Binds

Blood That Binds PDF Author: Melissa Winters
Publisher: Independently Published
ISBN:
Category : Fiction
Languages : en
Pages : 0

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Book Description
Vampires came for me, and I was sold at auction to their king. People tried for years to convince me that the monsters I see aren't real. They're wrong, but I allow them to believe what they want. I pretend the red-eyed creatures were figments of my imagination. That I'm healed from that terrible time in my life. The truth is, I know all too well that vampires exist. I thought that was the worst of my problems. Not even close. BLOOD THAT BINDS is book one in The Blood Legends series. A coming of age paranormal romance full of world-building and twists you won't see coming. *This book ends on a cliffhanger, but the series is complete. It contains violence, language and sexual content appropriate for 17+

Dark Instincts

Dark Instincts PDF Author: Suzanne Wright
Publisher: Montlake Romance
ISBN: 9781477828748
Category : Erotic stories
Languages : en
Pages : 0

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Book Description
Whenever wolf shifter Roni Axton is near Marcus Fuller, there's a crackle of sexual awareness that's intoxicating ... and deeply annoying. Marcus is a pack enforcer who oozes power, but Roni is lethal in her own right. His possessive gaze makes one thing clear. Marcus has singled her out for seduction, and he wants to make her sit up and beg. When a brutal attack by a jackal pack forces them to work together, it's the perfect opportunity for Marcus to chip away at her defenses-- until he falls into his own trap, completely unprepared for the intensity of their connection. For Marcus, claiming Roni once will mean needing her forever.

The Favor

The Favor PDF Author: Suzanne Wright
Publisher:
ISBN:
Category : Man-woman relationships
Languages : en
Pages : 294

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Book Description
Vienna Stratton knew she only had herself to blame. You didn’t let yourself become indebted to a man like Dane Davenport, no matter how badly you needed his help. As his personal assistant, she was very aware that the globally successful CEO was ruthless and unforgiving. Of course, if she’d known he’d request that she be his wife for twelve months, she’d have hesitated in accepting his help. Because what she’d learned from Dane was that the devil wasn’t ugly and terrorising. He was seductive and captivating. He hummed with whispers of temptation – the temptation to sin and surrender, to let him brand and possess you. He awakened every need and fantasy you had.He could even make you love him.

From Rags

From Rags PDF Author: Suzanne Wright
Publisher:
ISBN: 9781491003671
Category :
Languages : en
Pages : 278

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Book Description
Jaxxon Carter, barmaid, would like nothing more than to better her current situation. A one-bedroomed flat, a sleazy landlord, drug-addicted neighbors - not exactly a childhood dream. When a chance encounter leads to a modelling job, she is catapulted to the peak of success. She also finds herself the focus of lethally sensual Connor McKenzie, who she hasn't seen since he left their foster home and went on to become a Formula One driver. But she has no intention of giving in to the mindless need between them. He hurt her once, and she won't allow it to happen a second time. Confident, determined, compelling...Connor McKenzie isn't a man who deprives himself of what he wants. There was only one thing he ever resisted, and it was the one thing he wanted most: the unknowingly enticing Jaxxon. When he sees her on the cover of a magazine, it reawakens every urge he buried. She tries to keep him out of her life, but Connor can't let it go. He resisted her ten years ago for a good reason. But now that reason is no longer there, and he's resolute that nothing - not even Jaxxon - will stop him from having her.

Fractured

Fractured PDF Author: Suzanne Wright
Publisher:
ISBN: 9781532892066
Category :
Languages : en
Pages : 234

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Book Description
Since the moment Imani Prince joined the Grand High Vampires' legion, she's been drawn to the self-assured and darkly sexual Robert 'Butch' Richardson. Although he walked away from her a year ago after a short fling, she doesn't judge him for his difficulties with relationships. But now he's in her space, declaring that he wants her back and regrets his earlier mistakes. While Imani's past is trying to interfere with the present and the threat of a war is looming, she has to decide whether to give him what he's demanding: all she has to give. Butch has always struggled to connect with people, but something about the sensual and independent Imani pulls at him until she's become an obsession that he simply can't shake. But she was with another male, and watching them together was agonizing. When that relationship ends, Butch makes his move. Now he has to convince her to take a second chance on him, and he won't leave her alone until she does. As far as he's concerned, Imani's his and has always been his. He just needs to make her see that.

Cancer Immunology and Immunotherapy

Cancer Immunology and Immunotherapy PDF Author: Mansoor M. Amiji
Publisher: Academic Press
ISBN: 012823637X
Category : Medical
Languages : en
Pages : 550

Get Book Here

Book Description
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Comprehensive treaty covering all aspects of immuno-oncology (IO) - Novel strategies for delivery of IO therapeutics and vaccines - Forecasting on the future of nanotechnology and drug delivery for IO