The Biology of the Autistic Syndromes

The Biology of the Autistic Syndromes PDF Author: Christopher Gillberg
Publisher: Cambridge University Press
ISBN: 9781898683223
Category : Medical
Languages : en
Pages : 348

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Book Description
Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.

The Biology of the Autistic Syndromes

The Biology of the Autistic Syndromes PDF Author: Christopher Gillberg
Publisher: Cambridge University Press
ISBN: 9781898683223
Category : Medical
Languages : en
Pages : 348

Get Book Here

Book Description
Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.

Biology Autistic Syndromes

Biology Autistic Syndromes PDF Author: Christopher Gillberg
Publisher:
ISBN: 9780521412780
Category :
Languages : en
Pages :

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Book Description


The Biology of the Autistic Syndromes

The Biology of the Autistic Syndromes PDF Author: Christopher Gillberg
Publisher: Mac Keith Press
ISBN: 9780901260925
Category : Medical
Languages : en
Pages : 261

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Book Description


A Time for Metabolism and Hormones

A Time for Metabolism and Hormones PDF Author: Paolo Sassone-Corsi
Publisher: Springer
ISBN: 3319270699
Category : Medical
Languages : en
Pages : 141

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Book Description
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Cellular and Molecular Biology of Autism Spectrum Disorders

Cellular and Molecular Biology of Autism Spectrum Disorders PDF Author: Anna Strunecká
Publisher: Bentham Science Publishers
ISBN: 160805196X
Category : Science
Languages : en
Pages : 232

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Book Description
"Over the past several decades the incidence of autism spectrum disorders (ASD) has increased dramatically. The etiology of ASD remains an unsolved puzzle to scientists, physicians, pediatricians, psychiatrists, and pharmacologists. Our E-book will address"

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: Andreas M. Grabrucker
Publisher:
ISBN:
Category :
Languages : en
Pages : 117

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Book Description
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.

The Neurology of Autism

The Neurology of Autism PDF Author: Mary Coleman
Publisher: Oxford University Press
ISBN: 0199728399
Category : Psychology
Languages : en
Pages : 273

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Book Description
In Neurology of Autism, Mary Coleman, Catalina Betancur, G. Robert DeLong, Christopher Gillberg, Yoshiko Nomura, Lorenzo Pavone, Martin Ruggieri, and Michele Zappella use the tools of neurological analysis to address a number of the major questions that have arisen in the study of autism. The answers they present have important implications for the direction of future autism research, diagnosis, and treatment. What are the neurological signs and symptoms of autism? The latest information is presented here in an in-depth discussion of epilepsy, cranial circumference, changes in muscle tone, stereotypies, and mutism found in children with autism. In addition, a template is provided for practitioners to follow when conducting neurological examinations of a child with autism. What are the best options for the treatment of autism? The current medical, educational, and alternative therapies are thoroughly reviewed and evaluated. Is autism reversible? The question is explored for syndromic autism, where diseases may have a transient autistic phase, and reviewed in detail for nonsyndromic autism. Is autism primarily a single disease, as originally described by Leo Kanner? Research presented here suggests that autism is, instead, a syndrome involving many disease entities. Has the incidence of autism been increasing in recent years? A sophisticated, historical review of autisms prevalence rates suggests that it has never been rare. What is the relationship between autism and Asperger syndrome? The latest evidence presented here sheds light on the degree to which both syndromes share more than clinical characteristics; they also have some similar findings in imaging, neuropathological, and genetic studies. Which components of the brains neural networks need to be impaired to cause the appearance of autistic symptoms? Although there are many candidate regions, dysfunction of the cerebellum and its circuits is noted to be of great interest. Student and professional researchers, practitioners, and parents will find this book to be a valuable resource for both the latest information from basic-science research and its application to the diagnosis and treatment of autism. "[This book] includes up-to-date genetic evidence, underlining the complexities of genetic/environmental influences...I recommend this easy and informative read." -European Journal of Pediatric Neurology "...authoritative." -The Lancet Neurology "Coleman's new book is an absolute must-read for anyone interested in the progress made in understanding the causes of autism. The field owes her a tribute worthy of someone who has transformed an area of neuroscience." -Simon Baron-Cohen in Nature Neuroscience "[I]nformative and comprehensive in its treatment of the neurologic basis of autism...well written and easy to understand...the contributing authors have done an excellent job of making complex medical concepts understandable to all. The glossary at the end of the book is extremely helpful in this regard. The book is well referenced, provides helpful tables throughout, and includes a summary of relevant points at the end of each chapter.The authors are to be commended for presenting a very balanced view of current knowledge; they also indicate what we do not yet understand about brain functioning in autism and provide an important road map for ongoing exploration." -Marshalyn Yeargin-Allsopp in The New England Journal of Medicine "At last it is recognised that developmental neurology is the appropriate context in which to explain autism. The authors of this volume, all pioneers in the field, consider new ideas on autism in this context. They succeed in making surprising and illuminating comparisons between autism and neurological disorders whose origin is already known. This work is a significant step towards understanding the causes of autistic disorders."-Uta Frith, Institute of Cognitive Neuroscience and Department of Psychology, University College London "When and if the secret of autism is teased from the myriad disease states that exhibit the syndrome, it will be through efforts such as are represented in this volume. Dr. Coleman has 'picked the brains' of recognized experts from neurology and related sciences, and has assembled a wealth of up-to-date and meticulously referenced information regarding both those diseases and the core symptoms of autism." -Peter B. Rosenberger, Massachusetts General Hospital

Defining Autism

Defining Autism PDF Author: Emily L. Casanova
Publisher: Jessica Kingsley Publishers
ISBN: 1784503495
Category : Psychology
Languages : en
Pages : 264

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Book Description
Offering a summary of the current state of knowledge in autism research, Defining Autism looks at the different genetic, neurological and environmental causes of, and contributory factors to autism. It takes a wide-ranging view of developmental and genetic factors, and considers autism's relationship with other conditions such as epilepsy. Shedding light on the vast number of autism-related syndromes which are all too often denied adequate attention, it shows how, whilst autism refers to a single syndrome, it can be understood as many different conditions, with the common factors being biological, rather than behavioral.

Autism and Asperger Syndrome

Autism and Asperger Syndrome PDF Author: Simon Baron-Cohen
Publisher: Oxford University Press
ISBN: 019850490X
Category : Family & Relationships
Languages : en
Pages : 170

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Book Description
"In this book Simon Baron-Cohen summarizes the current understanding of autism and Asperger Syndrome. He explains the process of diagnosis, as well as the options for education and intervention for those with these conditions. Taking a lifespan approach, Professor Baron-Cohen considers how the conditions affect very young children through to adulthood. He also outlines his new Empathizing-Systemizing (ES) theory, which aims to explain all of the psychological features of autistic-spectrum conditions." "This book is designed firstly for people with these conditions and their families. It will be useful to clinicians, teachers, and other professionals involved in the care and support of people on the autistic-spectrum. The book will also provide an introduction to the topic for students in the social and biological sciences."--BOOK JACKET.

Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets

Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets PDF Author: Benjamin Gesundheit
Publisher: Frontiers Media SA
ISBN: 2889451127
Category :
Languages : en
Pages : 180

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Book Description
Autism Spectrum Disorder (ASD) is currently diagnosed based on a series of behavioral tests. The challenge for researchers is to try to uncover the biological basis for these typical behaviors in order to improve diagnosis and identify potential targets for treatment. A multidisciplinary approach is necessary in order to move forward. This includes analysis of the current animal models for ASD and their suitability, reviewing immunological, immunogenetic and epigenetic research, reassessing clinical diagnostic tools, and surveying radiological, pathological, and serological records for clues. This volume includes research from some of the leading researchers on ASD. We are hopeful that it will stimulate further dialogue and research in this challenging field.