Calling of the Ais

Calling of the Ais PDF Author: Cynthia Young
Publisher: Page Publishing Inc
ISBN: 1662407343
Category : Fiction
Languages : en
Pages : 290

Get Book Here

Book Description
When stylish and stunning Jemma discovers century-old Ais Indian artifacts on her oceanfront Florida property, she is compelled to know why. Incredibly, she finds herself traveling back in time over three hundred years through a tragic shipwrecked voyage back to her property and back to the savage Ais Indians.The handsome chief and his exotic princess are overwhelmed by this unexpected blonde, fair-skinned gift. Jemma is forced to live among them. What starts as a heathen tribal ritual binding the three evolves into an erotic sexual love triangle until history changes everything.

Calling of the Ais

Calling of the Ais PDF Author: Cynthia Young
Publisher: Page Publishing Inc
ISBN: 1662407343
Category : Fiction
Languages : en
Pages : 290

Get Book Here

Book Description
When stylish and stunning Jemma discovers century-old Ais Indian artifacts on her oceanfront Florida property, she is compelled to know why. Incredibly, she finds herself traveling back in time over three hundred years through a tragic shipwrecked voyage back to her property and back to the savage Ais Indians.The handsome chief and his exotic princess are overwhelmed by this unexpected blonde, fair-skinned gift. Jemma is forced to live among them. What starts as a heathen tribal ritual binding the three evolves into an erotic sexual love triangle until history changes everything.

Industrial Security Manual for Safeguarding Classified Information

Industrial Security Manual for Safeguarding Classified Information PDF Author: DIANE Publishing Company
Publisher: DIANE Publishing
ISBN: 9780788108228
Category : Technology & Engineering
Languages : en
Pages : 334

Get Book Here

Book Description


Mobility Analytics for Spatio-Temporal and Social Data

Mobility Analytics for Spatio-Temporal and Social Data PDF Author: Christos Doulkeridis
Publisher: Springer
ISBN: 3319735217
Category : Computers
Languages : en
Pages : 186

Get Book Here

Book Description
This book constitutes the refereed post-conference proceedings of the First International Workshop on Mobility Analytics for Spatio-Temporal and Social Data, MATES 2017, held in Munich, Germany, in September 2017. The 6 revised full papers and 2 short papers included in this volume were carefully reviewed and selected from 13 submissions. Also included are two keynote speeches. The papers intend to raise awareness of real-world problems in critical domains which require novel data management solutions. They are organized in two thematic sections: social network analytics and applications, and spatio-temporal mobility analytics.

BRIDGE MANAGEMENT MANUAL (FOR DECK CADETS & DECK RATINGS)

BRIDGE MANAGEMENT MANUAL (FOR DECK CADETS & DECK RATINGS) PDF Author: PHILIP JOHN DEQUINA RENDADO
Publisher: PHILIP RENDADO
ISBN:
Category : Juvenile Fiction
Languages : en
Pages : 416

Get Book Here

Book Description
DECK CADETS, DECK RATINGS &/OR INEXPERIENCED SEAFARERS THIS MANUAL IS FOR YOU My name is Philip Rendado, Author/Entrepreneur and former Third Officer. This book is a compilation of -knowledge never truly taught at school regarding being a deck officer -actual procedures on the bridge (used onboard) -actual procedures on how to do your job as a seafarer onboard the ship Remember once you go onboard the ship, the details may be slightly different from what you are going to experience, but for the most part it will be the same.

Transputer Research and Applications 5

Transputer Research and Applications 5 PDF Author: North American Transputer Users Group. Conference
Publisher: IOS Press
ISBN: 9789051990782
Category : Computers
Languages : en
Pages : 356

Get Book Here

Book Description
Parallel processing is now becoming a household word among computer researchers and designers. This work contains 29 contributions from leading experts in the field attending the 1992 NATUG conference.

NASA Technical Translation

NASA Technical Translation PDF Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 622

Get Book Here

Book Description


Future Federal Aviation Administration Telecommunications Plan

Future Federal Aviation Administration Telecommunications Plan PDF Author: United States. Federal Aviation Administration
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 860

Get Book Here

Book Description


Decisions and Orders of the National Labor Relations Board

Decisions and Orders of the National Labor Relations Board PDF Author: United States. National Labor Relations Board
Publisher:
ISBN:
Category : Labor laws and legislation
Languages : en
Pages : 1320

Get Book Here

Book Description


Functional Organization of Vertebrate Plasma Membrane

Functional Organization of Vertebrate Plasma Membrane PDF Author:
Publisher: Elsevier
ISBN: 0124171168
Category : Science
Languages : en
Pages : 393

Get Book Here

Book Description
Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume covers recent breakthroughs in understanding the molecular and cellular basis for patterning vertebrate plasma membranes. A special emphasis is placed on physiological function with chapters covering signaling in the nervous system and heart, vision, and the immune system. - consolidates subjects normally dispersed in the literature - presents in one volume a subject that has undergone a recent molecular revolution - authors are primary contributors and in some cases the founding figures in their fields

Neurobiology of the Axon in Health and Disease

Neurobiology of the Axon in Health and Disease PDF Author: Maren Engelhardt
Publisher: Frontiers Media SA
ISBN: 2889194884
Category :
Languages : en
Pages : 234

Get Book Here

Book Description
Ever since Santiago Ramón y Cajal sketched his captivating panels of the microscopic structure of the brain with its vast diversity of neuronal morphology over a century ago, scientists have been drawn to this seemingly chaotic network of neurites and processes to uncover how structure relates to function. During the course of a century, we have moved from merely describing neuronal and glial morphology to furthering our understanding of such intricate processes as organelle and factor transport, cellular compartmentalization, neuronal polarity, cytoskeleton dynamics, neurite pathfinding, and the impact of pathophysiological insult on these structures and events. Yet to this day, and likely for the foreseeable future, much work remains to be done to fully grasp the exceptional role of neurites for the function of larger neuronal ensembles and networks. While the somatodendritic domain of neurons has been in the focus of attention for many years, mostly because of its great dynamic remodeling capacity during events of plasticity (e.g. learning), the axonal domain has somehow remained in the background despite the fact that especially recent comprehensive studies from various fields of research underline the axon’s contribution to dynamic plasticity processes. Consequently, this Research Topic focuses on the many exciting aspects of axonal neurobiology – ranging from membrane composition and molecular determination during development to axonal domain specialization and physiology in health and disease. In Chapter 1 “Axons in the PNS”, Bombeiro et al. use immunodeficient mice to study the role of lymphocytes during the regeneration of peripheral nerves, showing that the modulation of immune responses after injury can be an efficient approach to enhance nerve regeneration in the PNS. Using a DRG model, Berbusse et al. identify the onset of damage to mitochondrial structure and dynamics as a key event during early axon degeneration and provide evidence that Nmnat1, a member of the family of nicotinamide-nucleotide adenylyltransferases, can have protective effects by preserving normal mitochondrial integrity and dynamics. In another study of PNS nerve regeneration, Law et al. use proteomics approaches via Mass Spectrometry to provide evidence that rosovitine, a synthetic purine nucleoside analog, can successfully promote PNS axon regeneration. In Chapter 2 “Axonal development in the central nervous system”, Yoshimura et al. analyze specialized axonal domains, namely the axon initial segment and nodes of Ranvier, with regards to their expression profiles of the major scaffolding protein ßIV-spectrin. Super resolution microscopy reveals a potential developmental switch of spectrin isoforms at both axonal domains. In a related study, also using super resolution microscopy, Leterrier et al. examine a potential reciprocal role of membrane partners in ankyrin-G targeting and stabilization at the axonal membrane during development. The authors demonstrate a tight and precocious association of ankyrin-G with its membrane partners. Höfflin et al. address the question of axon initial segment morphology across different cell classes in cortical organotypic slice cultures and find a surprising heterogeneity especially between pyramidal cells and interneurons in primary visual cortex. In a major step towards establishing a successful live label of the axon initial segment, Dumitrescu et al. report the development of a genetically-encoded construct consisting of a voltage-gated sodium channel intracellular domain fused to yellow fluorescent protein (YFP-NaVII-III). Nelson and Jenkins then provide a comprehensive Review article on the axon initial segment and nodes of Ranvier with a special focus on the various scaffolding protein isoforms and their role in human disease. In Chapter 3 “Axonal physiology and plasticity”, Nikitin et al. investigate fast onset dynamics of action potentials during neuronal development in vitro, showing that encoding of high frequencies improves upon culture maturation, accompanied by the development of passive electrophysiological properties and action potential generation. Using pharmacological and RNA interference approaches, Tapia et al. provide evidence that cannabinoid receptors and their ligands can modulate dendritic morphology and thus, indirectly, also affect ankyrin-G accumulation at the axon initial segment. A Mini Review by Zbili et al. discusses the potential impact of subthreshold changes in presynaptic membrane potential before action potential initiation on neurotransmitter release, and which significant impact such mechanisms could have on information processing in neuronal circuits. Yamada and Kuba close this chapter with a Mini Review on axon initial segment plasticity with a particular focus on ion channels and the biophysics of excitability. In Chapter 4 “Axon degeneration and regeneration”, Hamada et al. investigate the often overlooked question to which extent myelin loss affects action potential propagation along distal branch points and axon collaterals. Using the cuprizone demyelination model and optical voltage-sensitive dye imaging, the authors uncover functional consequences of demyelination that reach well beyond the main axon. In a model of mild traumatic brain injury, Vascak et al. demonstrate complex aspects of this injury type on neocortical circuit function, including changes in inhibitory perisomatic input and axon initial segment-driven output in affected layer V neurons. In a Mini Review, Grosch et al. discuss recent advances in the field of Parkinson’s disease with a focus on early degeneration in dopaminergic and serotonergic neurons of the basal ganglia. The last two articles cover the topic of axonal regeneration. Li et al. investigate the role of activated astrocytes in spinal cord lesion and how their functional downregulation via an inhibitor of mitochondrial fission, Mdivi-1, could potentially have positive impact on lesion scar formation and axonal regeneration. In a final Review, Liu et al. highlight recent advances in the development of biomaterial scaffolds and cell transplantation strategies to combine two promising therapeutic approaches for spinal cord injury.