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Author: Dr. Nilima Shukla , Mr. Shyam Wamanrao Rangari , Dr Baljinder Singh Bajwa , Dr. D. Sudhahar , Dr. Mejo Joseph
Publisher: Shashwat Publication
ISBN: 8119517431
Category : Medical
Languages : en
Pages : 177
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Book Description
The formulation development process is built upon the foundation of the pharmaceutical product development process. During the development of the product, the formulation scientist is responsible for paying attention to several parameters connected to the material (API, Excipients, and so on), the formulation process, the parameters of the formulation process, dosage forms, and so on. In this book, a variety of formulation development-related topics, including those pertaining to dosage, are broken down in a way that is clear and easy to grasp. I am hoping that both the students and the teachers will have positive reactions to this book. We are open to hearing recommendations regarding any and all aspects of the profession. We take full responsibility for any deviations or errors that may have been overlooked, and we would be extremely appreciative if readers would bring them to our attention if they did occur.
Author: V Alagarsamy
Publisher: Elsevier Health Sciences
ISBN: 813123259X
Category : Medical
Languages : en
Pages : 833
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Book Description
Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs. Salient Features Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs: Drugs acting on inflammation Drugs acting on respiratory system Drugs acting on digestive system Drugs acting on blood and blood-forming organs Drugs acting on endocrine system Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject Covers the syllabi of majority of Indian universities
Author: Marc Harrold
Publisher: ASHP
ISBN: 1585283649
Category : Medical
Languages : en
Pages : 405
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Book Description
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author: V Alagarsamy
Publisher: Elsevier Health Sciences
ISBN: 8131232581
Category : Medical
Languages : en
Pages : 1010
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Book Description
Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs. Salient Features Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs: Drugs acting on inflammation Drugs acting on respiratory system Drugs acting on digestive system Drugs acting on blood and blood-forming organs Drugs acting on endocrine system Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject Covers the syllabi of majority of Indian universities
Author: Andrew Davis
Publisher: Royal Society of Chemistry
ISBN: 1782621830
Category : Science
Languages : en
Pages : 789
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Book Description
Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
Author: Thomas Nogrady
Publisher: Oxford University Press
ISBN: 0190282967
Category : Medical
Languages : en
Pages : 664
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Book Description
Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
Author: V. ALAGARSAMY
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789385915505
Category : Medical
Languages : en
Pages :
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Book Description
This popular textbook for pharmacy students provides all the information they need to know about medicinal chemistry. The third edition features new layout and design in an attractive two-colour presentation. It contains clear classifications, synthetic schemes, modes of action, metabolism, assay, pharmacological uses with the dose and structure activity relationship (SAR) of the drugs for the various body systems. - Contains a complete section on drug design, describing the new drug development. - Includes an introduction to the physiological and pathophysiological conditions of diseases and their treatment. - Provides well-illustrated synthetic schemes and alternative synthetic routes for the majority of drugs. - Additional physico-chemical parameters have been explained.
Author: Dr. Nilima Shukla , Mr. Shyam Wamanrao Rangari , Dr Baljinder Singh Bajwa , Dr. D. Sudhahar , Dr. Mejo Joseph
Publisher: Shashwat Publication
ISBN: 8119517431
Category : Medical
Languages : en
Pages : 177
Get Book Here
Book Description
The formulation development process is built upon the foundation of the pharmaceutical product development process. During the development of the product, the formulation scientist is responsible for paying attention to several parameters connected to the material (API, Excipients, and so on), the formulation process, the parameters of the formulation process, dosage forms, and so on. In this book, a variety of formulation development-related topics, including those pertaining to dosage, are broken down in a way that is clear and easy to grasp. I am hoping that both the students and the teachers will have positive reactions to this book. We are open to hearing recommendations regarding any and all aspects of the profession. We take full responsibility for any deviations or errors that may have been overlooked, and we would be extremely appreciative if readers would bring them to our attention if they did occur.
Author: Dr. Gopi Reddy Alugubelli, Mr. Sushant Kumar Sharma, Dr. Susmita Basak, Ms. Priti. R. Shirsath, Dr. Arti Gupta
Publisher: Shashwat Publication
ISBN: 9360874000
Category : Fiction
Languages : en
Pages : 223
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Book Description
The introduction of the book "Medicinal Chemistry III" makes me incredibly happy. This book's content has been painstakingly created to conform to the Pharmacy Council of India's prescribed curriculum for students pursuing a bachelor's degree in pharmacy. To make the subject easier for students to understand, an attempt has been made to research it using as simple a vocabulary as possible. Many images throughout the book, including flowcharts and diagrams, help students understand difficult concepts. The genuine hope of the author is that readers of this book, academicians and students alike, will find something of value. The pharmaceutical product development process serves as the cornerstone for the formulation development process. The formulation scientist bears the responsibility of monitoring various material parameters (such as API and excipients), formulation process parameters, dosage forms, and other related aspects during the product development process. This book provides straightforward and understandable explanations of a wide range of formulation development-related subjects, including dose. I'm hopeful that this book will be well received by both teachers and students. We are willing to consider suggestions about any and all facets of the industry. Any faults or deviations that may have gone unnoticed are entirely our fault, and we would be very grateful if readers could point them out to us if they did.
Author: Dr. Gurinderdeep Singh, Mr. S. G. Raman , Professor Srinivasa Rao Atla , Dr. Ashish Ashok Gawai , Dr. K. Vijay Kishore
Publisher: Shashwat Publication
ISBN: 9360874450
Category : Medical
Languages : en
Pages : 256
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Book Description
Introducing the book "Medicinal Chemistry - II" is something that fills me with an incredible amount of joy. The content of this book has been meticulously crafted to adhere to the curriculum for Bachelor of Pharmacy students that has been outlined by the Pharmacy Council of India. An effort has been made to investigate the topic using terminology that is as straightforward as possible in order to make it more simply digestible for pupils. The book has a number of illustrations, such as flowcharts and diagrams that make it simple for students to comprehend complex ideas. It is the author's honest desire that both students and academicians would take something helpful away from reading this book.
Author: Mr. Sudam Gorakhnath Mule, Mr. Jagdish Atmaram Waghmare
Publisher: Shashwat Publication
ISBN: 9360876518
Category : Fiction
Languages : en
Pages : 353
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Book Description
The textbook Medicinal Chemistry – II offers a detailed exploration of various therapeutic agents and their pharmacological actions. It begins with antihistaminic agents, discussing histamine, its receptors, and a variety of H1 and H2 antagonists. It covers proton pump inhibitors and extends into antineoplastic agents, with a focus on alkylating agents, antimetabolites, and plant-derived products. Anti-anginal drugs, including vasodilators and calcium channel blockers, are examined next, followed by a section on diuretics. Other topics include antihypertensive drugs, antiarrhythmics, antihyperlipidemic agents, coagulants, anticoagulants, and drugs for treating congestive heart failure. The book also delves into endocrine system agents, with sections on sex hormones, corticosteroids, and drugs for erectile dysfunction. Antidiabetic agents, including insulin and oral hypoglycemics, are thoroughly covered. The text concludes with local anesthetics, emphasizing their structure-activity relationships and various chemical classes.
