Temperature and Species Comparisons of Benzocaine Pharmacokinetics, Metabolism and Physiologically Based Pharmacokinetic Model Within Channel Catfish, Ictalurus Punctatus, and Yellow Perch, Perca Flavescens PDF Download
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Author: Kelli J. Clark
Publisher:
ISBN:
Category :
Languages : en
Pages : 520
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Book Description
Abstract: Benzocaine, a local anesthetic for mammals, has potential for use as a general anesthetic in finfish. Its pharmacokinetics, metabolism, and residue profiles were characterized to support its approval in fish. To compare interspecies and temperature differences of these parameters channel catfish were studied at 16, 21, and 260C and yellow perch at 160C. The feasibility of "crop grouping" was investigated with a physiologically based pharmacokinetic (PBPK) model as a means to reduce the amount of testing required for aquaculture drug registration.
Author: Kelli J. Clark
Publisher:
ISBN:
Category :
Languages : en
Pages : 520
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Book Description
Abstract: Benzocaine, a local anesthetic for mammals, has potential for use as a general anesthetic in finfish. Its pharmacokinetics, metabolism, and residue profiles were characterized to support its approval in fish. To compare interspecies and temperature differences of these parameters channel catfish were studied at 16, 21, and 260C and yellow perch at 160C. The feasibility of "crop grouping" was investigated with a physiologically based pharmacokinetic (PBPK) model as a means to reduce the amount of testing required for aquaculture drug registration.
Author: Heidi S. Erickson
Publisher:
ISBN:
Category : Animal welfare
Languages : en
Pages : 460
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Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 992
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Book Description
Author: Øyvind Lie
Publisher: Elsevier
ISBN: 1845694929
Category : Technology & Engineering
Languages : en
Pages : 646
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Book Description
Global aquaculture production has grown rapidly over the last 50 years. It is generally accepted that there is limited potential to increase traditional fisheries since most fish stocks are well or fully exploited. Consequently increased aquaculture production is required in order to maintain global per capita fish consumption at the present level. Fish farming enables greater control of product quality and safety, and presents the possibility of tailoring products according to consumer demands. This important collection reviews safety and quality issues in farmed fish and presents methods to improve product characteristics.The first part of the book focuses on chemical contaminants, chemical use in aquaculture and farmed fish safety. After an opening chapter discussing the risks and benefits of consumption of farmed fish, subsequent contributions consider environmental contaminants, pesticides, drug use and antibiotic resistance in aquaculture. Part two addresses important quality issues, such as selective breeding to improve flesh quality, the effects of dietary factors including alternative lipids and proteins sources on eating quality, microbial safety of farmed products, parasites, flesh colouration and off-flavours. Welfare issues and the ethical quality of farmed products are also covered. The final part discusses ways of managing of product quality, with chapters on HACCP, monitoring and surveillance, authenticity and product labelling.With its distinguished editor and international team of contributors, Improving farmed fish quality and safety is a standard reference for aquaculture industry professionals and academics in the field. Reviews safety and quality issues in farmed fish and presents methods to improve product characteristics Discusses contaminants, persistent organic pollutants and veterinary drug residues and methods for their reduction and control Addresses important quality issues, genetic control of flesh characteristics and the effects of feed on product nutritional and sensory quality
Author: Richard T. Di Giulio
Publisher: CRC Press
ISBN: 0203647297
Category : Science
Languages : en
Pages : 1102
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Book Description
When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on
Author: D.J. Smith
Publisher: Springer Science & Business Media
ISBN: 1461547032
Category : Science
Languages : en
Pages : 226
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Book Description
Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation of environmental contaminants and food chemicals and researchers investigating the metabolism and disposition of foreign chemicals (xenobiotics) in fish species.
Author: William H. Clements
Publisher: John Wiley & Sons
ISBN: 0470855142
Category : Medical
Languages : en
Pages : 354
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Book Description
Ecotoxicology is the study of the effects of toxicants on ecological systems. Ecological effects of contaminants may occur at several levels of biological organisation, from individual organisms to the entire biosphere. Communities consist of interacting populations that overlap in time and space. Thus, community ecotoxicology is concerned with effects of contaminants on communities. This is one of a series of five books that will provide a comprehensive treatment of field ecotoxicology, it provides important insights into how contaminants affect the distribution and abundance of organisms in nature. * Both authors are well known highly respected scientists in the field. * The first book to be dedicated to 'community ecotoxicology.'
Author: Karline Soetaert
Publisher: Springer Science & Business Media
ISBN: 3642280706
Category : Computers
Languages : en
Pages : 258
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Book Description
Mathematics plays an important role in many scientific and engineering disciplines. This book deals with the numerical solution of differential equations, a very important branch of mathematics. Our aim is to give a practical and theoretical account of how to solve a large variety of differential equations, comprising ordinary differential equations, initial value problems and boundary value problems, differential algebraic equations, partial differential equations and delay differential equations. The solution of differential equations using R is the main focus of this book. It is therefore intended for the practitioner, the student and the scientist, who wants to know how to use R for solving differential equations. However, it has been our goal that non-mathematicians should at least understand the basics of the methods, while obtaining entrance into the relevant literature that provides more mathematical background. Therefore, each chapter that deals with R examples is preceded by a chapter where the theory behind the numerical methods being used is introduced. In the sections that deal with the use of R for solving differential equations, we have taken examples from a variety of disciplines, including biology, chemistry, physics, pharmacokinetics. Many examples are well-known test examples, used frequently in the field of numerical analysis.
Author: Frederick S.B. Kibenge
Publisher: Academic Press
ISBN: 0128213388
Category : Technology & Engineering
Languages : en
Pages : 250
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Book Description
Aquaculture Toxicology is an essential resource of practical information that covers mechanisms of toxicity and their responses to toxic agents, including aspects of uptake, metabolism and excretion of toxicants in fish, crustaceans and mollusks. This is a reliable, up-to-date, “all inclusive reference guide that provides an understanding of toxicology information for the aquaculture industry. Written by respected international experts recognized in specific areas of toxicology, this book covers toxins at the environmental, cellular and molecular levels. It identifies areas where more research is needed to generate more knowledge to support a sustainable aquaculture industry, including pharmaceutical pollutants and microplastics. Presents clinical information for the three major aquatic food animals (fish, crustaceans and mollusks) Discusses commonly used chemicals in aquaculture and their effects on aquatic animals and the environment Provides the latest advancements in the field of toxicity to facilitate fisheries and aquaculture research
Author: Geoffrey H. Satchell
Publisher: Cambridge University Press
ISBN: 9780521065542
Category : Science
Languages : en
Pages : 0
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Book Description
This book gives a concise account of the physiology and form of the fish circulatory system. The emphasis is primarily on function, but details of structure have been included. Following a revision of ideas on hemodynamics, attention is focused on the heart as the primary pump in the fish circulatory system. The fine structure and the electrical and ionic events of cardiac myocytes are described and the major events of the cardiac cycle are outlined. The structure of the peripheral vessels then follow and attention is devoted to the circulation in certain special areas such as the gills, the renal portal system, and the secondary blood system. There are also chapters devoted to the blood and the hemopoetic tissues and an account is given of the different types of retial systems that concentrate oxygen or heat in various parts of the body. Following a description of the autonomic nervous system, the circulatory responses to exercise and hypoxia are described. The book concludes with a discussion on the circulation of hagfish and how it illuminates our understanding of the functional and structural evolution of the circulatory system.
