Targeting Cardiac Proteotoxicity

Targeting Cardiac Proteotoxicity PDF Author: Xuejun Wang
Publisher: Frontiers Media SA
ISBN: 2889668061
Category : Science
Languages : en
Pages : 175

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Book Description

Targeting Cardiac Proteotoxicity

Targeting Cardiac Proteotoxicity PDF Author: Xuejun Wang
Publisher: Frontiers Media SA
ISBN: 2889668061
Category : Science
Languages : en
Pages : 175

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Book Description


New Drug Targets for Proteotoxicity in Cardiometabolic Diseases

New Drug Targets for Proteotoxicity in Cardiometabolic Diseases PDF Author: Jun Ren
Publisher: Frontiers Media SA
ISBN: 2889715833
Category : Science
Languages : en
Pages : 310

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Cardiovascular Pathology

Cardiovascular Pathology PDF Author: L. Maximilian Buja
Publisher: Academic Press
ISBN: 0323912583
Category : Science
Languages : en
Pages : 996

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Book Description
Cardiovascular Pathology, Fifth Edition provides a comprehensive treatise on the pathology of cardiovascular diseases, combining presentations of detailed pathology of cardiovascular diseases coupled with contemporary insights into etiology and pathogenesis. Twenty-two chapters cover general topics, including cardiovascular genetics, heart failure, and transplantation, and specific congenital and acquired cardiovascular diseases, therapeutic interventions, and forensic aspects. New chapters address the scope of practice and training in cardiovascular pathology, with a focus on major diagnostic approaches used in contemporary practice and research in cardiovascular pathology, and a perspective on the field of cardiovascular regenerative medicine linked to the basic pathobiology of cell-based therapy. The book provides a unique combination of details of pathological anatomy essential for pathologists involved in the evaluation of cardiovascular specimens and cardiovascular diseases, and is an excellent reference for anyone interested in the natural history and therapeutic advances in the cardiovascular field. - Includes expanded coverage of diagnostic guidelines, standards and normal values - Provides a summary of cardiac catheterization laboratory and diagnostic imaging tests to guide pathologists in clinicopathological correlation - Presents a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows in pathology, cardiology, cardiac surgery, and internal medicine - Provides comprehensive coverage, including, when appropriate, Central Concept Figure, Definition, Epidemiology, Clinical Presentation, Pathogenesis, Molecular Genetics, Light and Electron Microscopy, Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications, and a Bulleted Summary

Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application

Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application PDF Author: Gianluigi Pironti
Publisher: Frontiers Media SA
ISBN: 2889665267
Category : Science
Languages : en
Pages : 164

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Post-Translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease

Post-Translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease PDF Author: Huabo Su
Publisher: Frontiers Media SA
ISBN: 2889715000
Category : Science
Languages : en
Pages : 150

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Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)

Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM) PDF Author: VijayaKumar Sukumaran
Publisher: Frontiers Media SA
ISBN: 2889764974
Category : Medical
Languages : en
Pages : 185

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Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations

Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations PDF Author: Leonardo Roever
Publisher: Frontiers Media SA
ISBN: 2889453316
Category :
Languages : en
Pages : 119

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Book Description
The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.

Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis PDF Author: Rupinder K. Sodhi
Publisher: Academic Press
ISBN: 0128157631
Category : Medical
Languages : en
Pages : 434

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Book Description
Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. - Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments - Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo - Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

Metabolic Cardiomyopathy

Metabolic Cardiomyopathy PDF Author: H. Böhles
Publisher: CRC Press
ISBN: 9783887631048
Category : Medical
Languages : en
Pages : 188

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Book Description
During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Targeted drug discovery in ectopic calcification: Mechanism, prospect, and clinical application

Targeted drug discovery in ectopic calcification: Mechanism, prospect, and clinical application PDF Author: Kang Xu
Publisher: Frontiers Media SA
ISBN: 2832524214
Category : Science
Languages : en
Pages : 173

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Book Description