Tamoxifen for the Treatment and Prevention of Breast Cancer

Tamoxifen for the Treatment and Prevention of Breast Cancer PDF Author: Virgil Craig Jordan
Publisher: Oncology Group
ISBN: 9781891483004
Category : Breast
Languages : en
Pages : 309

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Book Description
Intended for the physician whose primary discipline is not medical oncology, but whose practice includes women at risk for breast cancer and/or women who are either taking tamoxifen to treat breast cancer, or women who are taking raloxifene to prevent osteoporosis. Also recommended for nurses in breast care centers who are responsible for the day-to-day care of women.

Tamoxifen for the Treatment and Prevention of Breast Cancer

Tamoxifen for the Treatment and Prevention of Breast Cancer PDF Author: Virgil Craig Jordan
Publisher: Oncology Group
ISBN: 9781891483004
Category : Breast
Languages : en
Pages : 309

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Book Description
Intended for the physician whose primary discipline is not medical oncology, but whose practice includes women at risk for breast cancer and/or women who are either taking tamoxifen to treat breast cancer, or women who are taking raloxifene to prevent osteoporosis. Also recommended for nurses in breast care centers who are responsible for the day-to-day care of women.

Tamoxifen and Breast Cancer

Tamoxifen and Breast Cancer PDF Author: Michael W. DeGregorio
Publisher: Yale University Press
ISBN: 9780300079517
Category : Medical
Languages : en
Pages : 132

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Book Description
A discussion of the diagnosis of breast cancer and the risks, benefits and limitations of treatment alternatives, particularly tamoxifen. This edition contains information on developments in the use of tamoxifen, especially in the results of the Breast Cancer Prevention Trial.

Tamoxifen

Tamoxifen PDF Author: Philipp Y. Maximov
Publisher: Springer Science & Business Media
ISBN: 3034806647
Category : Medical
Languages : en
Pages : 218

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Book Description
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.

Davis's Drug Guide for Rehabilitation Professionals

Davis's Drug Guide for Rehabilitation Professionals PDF Author: Charles D. Ciccone
Publisher: F.A. Davis
ISBN: 0803640048
Category : Medical
Languages : en
Pages : 1217

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Book Description
A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

SEER, Surveillance, Epidemiology, and End Results Program

SEER, Surveillance, Epidemiology, and End Results Program PDF Author: SEER Program (National Cancer Institute (U.S.))
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 16

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Book Description


Tamoxifen

Tamoxifen PDF Author: John A. Kellen
Publisher: Springer Science & Business Media
ISBN: 1461240921
Category : Medical
Languages : en
Pages : 383

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Book Description
Tamoxifen has persisted as a widely accepted and administered drug for almost 25 years. Following the many scientific papers and books on the subject, it has remained a very intriguing substance. This, perhaps, is the reason for another monograph on Tamoxifen. It is regrettably true that overviews, even when up to date after exhaustive research - the shibboleth of our cultures -, rapidly lose relevance with the passage of time. Scientists can sometimes be pictured as deep sea divers, who plunge into the unknown in search of a hitherto unknown world. Their descent is exciting, but eventually they must come up for air and integrate their experiences with others who also had to resurface. This book intends to collect and, where possible, to collate recent, but sometimes seemingly unrelated information. To quote Stephane Mallarme: "Everything in the world exists to end up in a book". Even if this is a tad cynical, it might not be far from the truth. If a little knowledge is a dangerous commodity, one can also add - tongue in cheek - that a vast amount of knowledge can be truly hazardous. It is likely that what might seem as entangled data is confusing, especially for those satisfied with the comfortable interpretation of Tamoxifen as an antiestrogen which has long been found insufficient. The complexity of its mechanisms and effects defies simple explanations and may even seem capricious, but only because of our ignorance.

Long-term Tamoxifen Treatment for Breast Cancer

Long-term Tamoxifen Treatment for Breast Cancer PDF Author: Virgil Craig Jordan
Publisher: Univ of Wisconsin Press
ISBN: 9780299140700
Category : Health & Fitness
Languages : en
Pages : 320

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Book Description
During the past twenty years tamoxifen has become the most widely prescribed and most successful drug used in the treatment of breast cancer. In this volume, editor V. Craig Jordan provides articles that trace the development, pharmacology, and clinical research surrounding this drug which, by the year 2000, could be used to treat as many as one million women annually. Drawing from research conducted by specialists in the United States, the United Kingdom, and Italy, the series of articles describes the clinical testing of tamoxifen, highlighting the benefits. Studies show that tamoxifen lowers cholesterol and can potentially protect women against osteoporosis and fatal coronary heart disease. Equally important is a discussion of side effects and possible drug interactions and how these issues relate to patient concerns. An investigation of the development of a new class of drugs for use after tamoxifen fails provides valuable insight into future treatments, as the contributers consider possible resistance to tamoxifen. This volume provides invaluable information for physicians and surgeons who care for patients with breast cancer and for women interested in exploring this therapeutic dimension.

Tamoxifen Tales

Tamoxifen Tales PDF Author: V. Craig Jordan
Publisher: Elsevier
ISBN: 0323996175
Category : Business & Economics
Languages : en
Pages : 312

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Book Description
Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan's 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women's healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career. Highlights lessons learned from the journey behind discovery science that are applicable to the scientific journey of the next generation of scientists Provides a manual on the successful mentoring of young scientists to become leaders in academia and the pharmaceutical industry Examines cancer treatment based on a personal determination to challenge at the frontiers of the science and to relate to personal life experience Includes references for further research reading

Probably Someday Cancer

Probably Someday Cancer PDF Author: Kim Horner
Publisher: University of North Texas Press
ISBN: 1574417576
Category : Biography & Autobiography
Languages : en
Pages : 209

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Book Description
After learning that she inherited a BRCA2 genetic mutation that put her at high risk for breast and ovarian cancer, Kim Horner’s doctors urged her to consider having a double mastectomy. But how do you decide whether to have a surgery to remove your breasts to reduce your risk for a disease you don’t have and may never get? Horner shares her struggle to answer that question in Probably Someday Cancer. The mother of a one-year-old boy, she wanted to do whatever would give her the best odds of being around for her son and protect her from breast cancer, which killed her grandmother and great-grandmother in their 40s. Which would give her the best chance at a long healthy life: a double mastectomy or frequent screenings to try to catch any cancer early? The answers weren’t that simple. Based on extensive research, interviews, and personal experience, Horner writes about how and why she ultimately opted for a double mastectomy—the same decision actress Angelina Jolie made for a similar genetic mutation—and the surprising diagnosis that followed. The book explores difficult truths that get overshadowed by upbeat messages about early detection and survivorship—the fact that screenings can miss cancers and that even early-stage breast cancers can spread and become fatal. Probably Someday Cancer is about the author’s efforts to push past her fear and anxiety. This book can help anyone facing hereditary risk of breast and ovarian cancer feel less alone and make informed decisions to protect their health and end the devastation that hereditary cancer has caused for generations in so many families.

Hepatotoxicity

Hepatotoxicity PDF Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850

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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.