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Author: Owen A. O'Connor
Publisher: John Wiley & Sons
ISBN: 1119671310
Category : Medical
Languages : en
Pages : 434
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Book Description
THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.
Author: Owen A. O'Connor
Publisher: John Wiley & Sons
ISBN: 1119671310
Category : Medical
Languages : en
Pages : 434
Get Book Here
Book Description
THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.
Author: P.L. Haun
Publisher: Karger Medical and Scientific Publishers
ISBN: 1912776316
Category : Medical
Languages : en
Pages : 112
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Book Description
Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient. ' Fast Facts: Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists, and oncologists to communicate effectively with pathologists in the diagnosis of this chronic condition, aided by over 100 superb clinical and pathological images, and to provide tailored long-term care for their patients. This concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology, immunophenotyping and treatment of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is essential reading for pathologists, non-specialist clinicians and dermatology and oncology trainees.
Author: Herschel S. Zackheim
Publisher: CRC Press
ISBN: 1040160883
Category : Medical
Languages : en
Pages : 155
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Book Description
Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in
Author: Foss, Francine
Publisher: Karger Medical and Scientific Publishers
ISBN: 1912776189
Category : Medical
Languages : en
Pages : 101
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Book Description
The peripheral T-cell lymphomas (PTCLs) are a heterogenous group of rare entities. Whilst cytogenetic and molecular identifiers are being identified, accurate diagnosis remains challenging, requiring careful, expert integration of the clinical and pathological findings. The treatment of PTCL is also challenging. Protocols for the different subtypes are only just beginning to emerge, hindered by the complexities of conducting trials in such uncommon and varied conditions. While first-line treatment with conventional chemotherapy is seldom curative, patients who achieve remission may be eligible for stem cell transplantation, offering the possibility of long-term disease control if not cure. Targeted biologics are also being developed as unique cytotoxic markers are identified. 'Fast Facts: Peripheral T-Cell Lymphomas' is a new title in the Fast Facts extensive hemato-oncology library, written by experts in this emerging field. This handbook will be useful to anyone involved in the care of patients with PTCL, including haematologists, oncologists, specialist nurses and primary care providers, raising awareness of these rare lymphomas and the current – and emerging – approaches to diagnosis and treatment.
Author: E. Carstens
Publisher: CRC Press
ISBN: 1466505435
Category : Science
Languages : en
Pages : 482
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Book Description
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Author: Pier Paolo Piccaluga
Publisher: BoD – Books on Demand
ISBN: 1838812253
Category : Medical
Languages : en
Pages : 134
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Book Description
In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas.
Author: Haipeng Shao
Publisher:
ISBN: 9781536118995
Category : Lymphomas
Languages : en
Pages : 0
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Book Description
Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of Non-Hodgkin lymphomas with a variety of clinical presentation and outcomes. The diagnosis and treatment of CTCLs have evolved significantly with advances in our understanding of their pathogenesis and biological behaviors through immunophenotypic, molecular, and cytogenetic analysis and clinical correlation. The diagnosis and classification of CTCLs depend on integration of clinical presentation, histology, immunophenotype, molecular and/or cytogenetic findings. Accurate diagnosis and staging are essential for proper treatment and prognosis of the patients. The book Cutaneous T-Cell Lymphoma (CTCL): Clinical Features, Diagnosis and Treatment Options aims to provide the most up-to-date knowledge of the diagnosis, prognosis and treatment strategies of CTCL. Each chapter focuses on a different aspect of CTCL: clinical presentation, pathology, therapeutic options, role of radiation therapy, and in-depth discussion of the specific subtypes of CTCL classified under the most recent World Health Organization (WHO) classification of lymphoid neoplasms. The authors are practicing physicians in major medical centers and university hospitals, and are familiar with the challenges of diagnosing and treating patients with CTCL. The book is written for the practicing physicians and provides practical information and advice for their daily practice. Residents, fellows and other trainees will also find the contents of this book useful for their education and board preparation. The authors hope that the material covered in this book will serve as a foundation for the readers to keep up with future developments in the field.
Author: Lorenzo Cerroni
Publisher: John Wiley & Sons
ISBN: 1405140267
Category : Medical
Languages : en
Pages : 194
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Book Description
Skin lymphomas are relatively rare. They may arise in the skin itself and as a by-product of HIV infection, or may arise elsewhere as a result of Hodgkin's disease, B cell lymphomas or leukaemia. Whatever the cause, they can easily be overlooked as psoriasis or dermatitis. Diagnosis of skin lymphoma is difficult and making the wrong diagnosis can prove fatal. Consequently, those in training in dermatology and pathology need to have a good understanding of the clinical presentations and the pathological correlates of this challenging disease. An Illustrated Guide to Skin Lymphoma is a beautiful full-colour illustrated text and atlas that combines pathology with clinical features and treatment. This second edition includes the latest classification systems for cutaneous lymphomas as well as brand new chapters and an expanded section on treatment.
Author: Antonio Subtil
Publisher: Springer
ISBN: 3030116549
Category : Medical
Languages : en
Pages : 320
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Book Description
This volume is the first of its kind to emphasize the visual approach in the diagnosis of cutaneous lymphoid infiltrates. Written and designed in an accessible yet highly detailed format by an expert in the field, this book bridges the knowledge gaps so often found when dealing with skin lymphomas. Complete with more than two hundred high quality images and illustrations, Diagnosis of Cutaneous Lymphoid Infiltrates offers pearls and pitfalls as well as differential diagnoses. Additionally, images are explained and decoded with the use of illustrations and analogies, proving to be an invaluable resource for pathologists, dermatologists, dermatopathologists, hematopathologists, and residents and fellows in these fields.
Author: Robert A. Norman
Publisher: Springer Science & Business Media
ISBN: 1447145798
Category : Medical
Languages : en
Pages : 334
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Book Description
This is a comprehensive, practical, densely illustrated diagnostic and therapeutic guide for all geriatric dermatology providers. The book comprises 50 chapters and over 600 color photographs on topics ranging from common conditions such as basal cell carcinoma, rosacea, and seborrheic dermatitis to unusual conditions such as angiosarcoma, dermatofibrosarcoma protuberans, and porphyria cutanea tarda. Sections include: - Inflammatory conditions (including contact dermatitis, alopecia, erythema multiforme, pemphigus, bullous pemphigoid, porphyria, pruritus, psoriasis, rosacea, seborrhea, urticaria, xerosis, and more) - Infections (fungus, herpes simplex and zoster, scabies, lice, and warts) - Skin signs in systemic disease (skin tags, cutaneous metastases, xanthomas) - Regional dermatoses (intertrigo, leg ulcers, pressure sores) - Benign tumors (chondrodermatitis, cysts, ganglion, fibrous papule, seborrheic keratoses, lentigines, and benign vascular lesions) - Pre-malignant and malignant tumors (actinic keratoses, angiosarcoma, basal cell carcinoma, dermatofibroma and dermatofibrosarcoma protuberans, intraepidermal neoplasia, Kaposi's sarcoma, keratoacanthoma, lentigo maligna, cutaneous lymphoma, Mycosis fiungoides, melanoma, nevi and moles, and squamous cell carcinoma)
