Synthesis of Bioactive Scaffolds

Synthesis of Bioactive Scaffolds PDF Author: Rakesh Kumar Sharma
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110797429
Category : Science
Languages : en
Pages : 414

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Book Description
Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of synthetic organic chemistry. Scientists are constantly developing and improving these techniques in order to maximize the diversity of synthetically available molecules. These techniques must be developed in a sustainable manner in order to limit their environmental impact. This book highlights green bond forming reactions for bioactive scaffolds.

Synthesis of Bioactive Scaffolds

Synthesis of Bioactive Scaffolds PDF Author: Rakesh Kumar Sharma
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110797429
Category : Science
Languages : en
Pages : 414

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Book Description
Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of synthetic organic chemistry. Scientists are constantly developing and improving these techniques in order to maximize the diversity of synthetically available molecules. These techniques must be developed in a sustainable manner in order to limit their environmental impact. This book highlights green bond forming reactions for bioactive scaffolds.

Bioactive Glasses

Bioactive Glasses PDF Author: Heimo Ylänen
Publisher: Woodhead Publishing
ISBN: 0081009372
Category : Technology & Engineering
Languages : en
Pages : 428

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Book Description
Bioactive Glasses: Materials, Properties and Applications, Second Edition provides revised, expanded and updated content on the current status of this unique material, including its properties, technologies and applications. The book is suitable for those active in the biomaterials and bioengineering field, and includes eight new chapters that cover material types, computational modeling, coatings and applications. Chapters deal with the materials and mechanical properties of bioactive glass and the applications of bioactive glasses, covering their uses in wound healing, maxillofacial surgery and bone tissue engineering, among other topics. With its distinguished editor and expert team of international contributors, the book is an invaluable reference for researchers and scientists in the field of biomaterials, both in academia and industry. - Provides a detailed review of bioactive glasses, their properties, technologies and applications - Comprehensively covers the materials and mechanical properties of bioactive glass and their further applications, including wound healing, maxillofacial surgery and bone tissue engineering - Suitable for those active in the biomaterials and bioengineering field

Green Chemistry: Synthesis of Bioactive Heterocycles

Green Chemistry: Synthesis of Bioactive Heterocycles PDF Author: K. L. Ameta
Publisher: Springer
ISBN: 8132218507
Category : Science
Languages : en
Pages : 418

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Book Description
The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.

Privileged Scaffolds in Medicinal Chemistry

Privileged Scaffolds in Medicinal Chemistry PDF Author: Stefan Bräse
Publisher: Royal Society of Chemistry
ISBN: 1782620303
Category : Medical
Languages : en
Pages : 486

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Book Description
This book addresses the various classes of privileged scaffolds and covers the history of their discovery and use.

Electrospinning for Tissue Regeneration

Electrospinning for Tissue Regeneration PDF Author: L Bosworth
Publisher: Elsevier
ISBN: 085709291X
Category : Technology & Engineering
Languages : en
Pages : 425

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Book Description
Electrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector.The book opens with an introduction to the fundamentals of electrospinning. Chapters go on to discuss polymer chemistry, the electrospinning process, conditions, control and regulatory issues. Part two focuses specifically on electrospinning for tissue regeneration and investigates its uses in bone, cartilage, muscle, tendon, nerve, heart valve, bladder, tracheal, dental and skin tissue regeneration before concluding with a chapter on wound dressings. Part three explores electrospinning for in vitro applications. Chapters discuss cell culture systems for kidney, pancreatic and stem cell research.With its distinguished editors and international team of expert contributors, Electrospinning for tissue regeneration is a valuable reference tool for those in academia and industry concerned with research and development in the field of tissue repair and regeneration. - Provides a comprehensive overview of this innovative approach to tissue repair and regeneration covering issues from polymer chemistry to the regulatory process - Examines employment within the biomaterials sector, reviewing extensive applications in areas such as uses in bone, muscle tendon, heart valve and tissue regeneration - Explores electrospinning for in vitro applications and discusses cell culture systems for kidney, pancreatic and stem cell research

Diversity-Oriented Synthesis

Diversity-Oriented Synthesis PDF Author: Andrea Trabocchi
Publisher: John Wiley & Sons
ISBN: 1118618149
Category : Science
Languages : en
Pages : 550

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Book Description
Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

Magnetic Nanoparticles in Human Health and Medicine

Magnetic Nanoparticles in Human Health and Medicine PDF Author: Costica Caizer
Publisher: John Wiley & Sons
ISBN: 1119754747
Category : Science
Languages : en
Pages : 512

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Book Description
Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.

Bone Tissue Engineering

Bone Tissue Engineering PDF Author: Jeffrey O. Hollinger
Publisher: CRC Press
ISBN: 1135501912
Category : Medical
Languages : en
Pages : 462

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Book Description
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine

Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine PDF Author: Gilson Khang
Publisher: CRC Press
ISBN: 1315341026
Category : Medical
Languages : en
Pages : 872

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Book Description
Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application

The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application PDF Author: Shunsheng Cao
Publisher: Bentham Science Publishers
ISBN: 160805876X
Category : Medical
Languages : en
Pages : 355

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Book Description
Frontiers in Biomaterials: The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application, Volume 1 highlights the importance of biomaterials and their interaction with biological system. The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. This eBook covers the latest challenges on the biocompatibility of scaffold overtime after implantation and discusses the requirement of innovative technologies and strategies for the development of materials with long-lasting scaffold and biocompatibility functions. The contents of this eBook include chapters on cell-scaffold interactions in three dimensions, nanocrystalline diamond films for biomedical applications, bioceramics-design, synthesis and biological applications, polyester biomaterials for regenerative medicine, nanomaterials for skin regeneration and many more. This book is a valuable resource for MSc and PhD students , academic personnel and researchers seeking updated and critically important information on biomaterials and biomedical applications.