Synthesis, Characterization and Antimicrobial Studies of "click" 2-pyridyl-1,2,3-triazole Metal Complexes

Synthesis, Characterization and Antimicrobial Studies of Author: Sreedhar Kumar Vellas
Publisher:
ISBN:
Category :
Languages : en
Pages : 374

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Book Description
The rapid emergence of drug resistant bacterial strains poses serious challenges to human society. The increased mortality rates caused by drug resistant bacterial infections and the depleted rate of new antibacterial drugs indicates a pressing need to focus on feasible therapeutic alternatives to counter this problem. Metal complexes offer a different steric and electronic profile which could be useful in the generation of new and effective antibacterial agents. Additionally, the unique metal specific mode of action of metal based antimicrobial agents makes them less prone to bacterial resistance and encourages the development of these complexes as clinically relevant antibacterial agents. The work presented in this thesis was undertaken with the aim of developing functionalized metal complexes using the "click" chemistry approach, with a view towards investigating the application of these complexes as potential antimicrobial agents.

Synthesis, Characterization and Antimicrobial Studies of "click" 2-pyridyl-1,2,3-triazole Metal Complexes

Synthesis, Characterization and Antimicrobial Studies of Author: Sreedhar Kumar Vellas
Publisher:
ISBN:
Category :
Languages : en
Pages : 374

Get Book Here

Book Description
The rapid emergence of drug resistant bacterial strains poses serious challenges to human society. The increased mortality rates caused by drug resistant bacterial infections and the depleted rate of new antibacterial drugs indicates a pressing need to focus on feasible therapeutic alternatives to counter this problem. Metal complexes offer a different steric and electronic profile which could be useful in the generation of new and effective antibacterial agents. Additionally, the unique metal specific mode of action of metal based antimicrobial agents makes them less prone to bacterial resistance and encourages the development of these complexes as clinically relevant antibacterial agents. The work presented in this thesis was undertaken with the aim of developing functionalized metal complexes using the "click" chemistry approach, with a view towards investigating the application of these complexes as potential antimicrobial agents.

Synthesis, Characterisation and Antimicrobial Studies of Click 2,6-bis(1,2,3-triazol-4yl)pyridine Ruthenium(II) Complexes

Synthesis, Characterisation and Antimicrobial Studies of Click 2,6-bis(1,2,3-triazol-4yl)pyridine Ruthenium(II) Complexes PDF Author: Quinn Vernon Charle van Hilst
Publisher:
ISBN:
Category :
Languages : en
Pages : 176

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Book Description


Radically Different—A Themed Issue in Honor of Professor Bernd Giese on the Occasion of His 80th Birthday

Radically Different—A Themed Issue in Honor of Professor Bernd Giese on the Occasion of His 80th Birthday PDF Author: Katharina M. Fromm
Publisher: MDPI
ISBN: 3039363085
Category : Science
Languages : en
Pages : 284

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Book Description
This Special Issue came together thanks to contributions from friends and colleagues of Prof. Bernd Giese on behalf of his 80th birthday on 2 June 2020. Reflecting on the varied interests of Bernd in all areas of chemistry, this issue contains work, including historical work, on inorganic coordination chemistry, nanomaterials, theory, and organic and radical chemistry—Bernd’s core expertise. It is wonderful that so many different publications came together from all over the world, as both review articles and original contributions, making this Special Issue worthwhile reading.

Click Triazoles

Click Triazoles PDF Author: Janez Košmrlj
Publisher: Springer
ISBN: 3642294294
Category : Science
Languages : en
Pages : 245

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Book Description
B. R. Buckley and H. Heaney: Mechanistic Investigations of Copper(I)- Catalyzed Alkyne–Azide Cycloaddition Reactions.- J. D. Crowley and D. A. McMorran: “Click-Triazole” Coordination Chemistry: Exploiting 1,4-Disubstituted-1,2,3-Triazoles as Ligands.- S. Lee and A. H. Flood: Binding Anions in Rigid and Reconfigurable Triazole Receptors.- M. Watkinson: Click Triazoles as Chemosensors.- H.-F. Chow, C.-M. Lo and Y. Chen: Triazole-Based Polymer Gels.- T. Zheng, S. H. Rouhanifard, A. S. Jalloh, P. Wu: Click Triazoles for Bioconjugation.- S. Mignani, Y. Zhou, T. Lecourt and L. Micouin: Recent Developments in the Synthesis 1,4,5-Trisubstituted Triazoles.

Synthesis, Characterization and Antimicrobial Activity of Transition Metal Complexes of Substituted Benzoyl (N-substituted) Thiosemicarbazones

Synthesis, Characterization and Antimicrobial Activity of Transition Metal Complexes of Substituted Benzoyl (N-substituted) Thiosemicarbazones PDF Author: Sanjay Kumar
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Supramolecular Metal-Based Entities for Biomedical and Biological Applications

Supramolecular Metal-Based Entities for Biomedical and Biological Applications PDF Author: Angela Casini
Publisher: Frontiers Media SA
ISBN: 2889458997
Category :
Languages : en
Pages : 119

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Book Description
Research in the discovery of metal supramolecular complexes, mainly formed by the self-assembly of inorganic metal compounds with either inorganic or organic molecules via coordination (or organometallic) bonds, is a rapidly developing and newly rising highlight interdisciplinary field. This Reseach Topic is aimed at providing representative examples of supramolecular metal-based entities for different biological and biomedical applications.

Suprastars of Chemistry

Suprastars of Chemistry PDF Author: Tony D. James
Publisher: Frontiers Media SA
ISBN: 2889764567
Category : Science
Languages : en
Pages : 117

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Book Description
The field of Supramolecular Chemistry has rapidly evolved over the last 2 decades to the point where it is now influences a diverse range of research areas, drives technological breakthroughs, and often results in breathtaking feats of ingenuity along the way. None of these advancements would be possible without the creativity and talent of Supramolecular Chemists throughout the world, and this Research Topic aims to celebrate those scientists leading the way - the "Suprastars." Contributors to this collection were nominated by the Editorial Board of Frontiers in Chemistry, and by showcasing their work here, we aim to provide both a snapshot of the current field and also a glimpse what the next decade might hold. We welcome Original Research and Review articles, in themes including but not limited to: · Host-guest systems and host-guest interactions · Threaded molecules and slide-ring materials · Supramolecular polymers · Metallocycles and metallocages · Molecular machines and motors · Molecular sensors (chemosensors) · Nanoreactors and nanocarriers · Supramolecular catalysts · Metal-ligand assemblies · Self-assembly and directed self-assembly · Dynamic combinatorial chemistry · Foldamers · Biological supramolecular chemistry (including DNA and enzymes) · Experimental and theoretical aspects of bonding in supramolecular chemistry · Supramolecular chemistry at surfaces · Charged (anion and cation) and small molecule receptor chemistry · Developments in theoretical and practical aspects of supramolecular chemistry

Synthesis, Characterization and Thermolysis of Triazole Metal Complexes

Synthesis, Characterization and Thermolysis of Triazole Metal Complexes PDF Author: Graylon Kirk Williams
Publisher:
ISBN:
Category :
Languages : en
Pages : 248

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Book Description


Metallomacrocycles

Metallomacrocycles PDF Author: Hai-Bo Yang
Publisher: Royal Society of Chemistry
ISBN: 1782628584
Category : Science
Languages : en
Pages : 304

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Book Description
A comprehensive overview of metallomacrocycles from designing complex functional metallosupramolecular systems to their applications.

Chemistry of 1,2,3-triazoles

Chemistry of 1,2,3-triazoles PDF Author: Wim Dehaen
Publisher: Springer
ISBN: 331907962X
Category : Science
Languages : en
Pages : 389

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Book Description
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.