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Author: David G. Kleinbaum
Publisher: Springer Science & Business Media
ISBN: 1475725558
Category : Medical
Languages : en
Pages : 332
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Book Description
A straightforward and easy-to-follow introduction to the main concepts and techniques of the subject. It is based on numerous courses given by the author to students and researchers in the health sciences and is written with such readers in mind. A "user-friendly" layout includes numerous illustrations and exercises and the book is written in such a way so as to enable readers learn directly without the assistance of a classroom instructor. Throughout, there is an emphasis on presenting each new topic backed by real examples of a survival analysis investigation, followed up with thorough analyses of real data sets. Each chapter concludes with practice exercises to help readers reinforce their understanding of the concepts covered, before going on to a more comprehensive test. Answers to both are included. Readers will enjoy David Kleinbaums style of presentation, making this an excellent introduction for all those coming to the subject for the first time.
Author: David G. Kleinbaum
Publisher: Springer Science & Business Media
ISBN: 1475725558
Category : Medical
Languages : en
Pages : 332
Get Book Here
Book Description
A straightforward and easy-to-follow introduction to the main concepts and techniques of the subject. It is based on numerous courses given by the author to students and researchers in the health sciences and is written with such readers in mind. A "user-friendly" layout includes numerous illustrations and exercises and the book is written in such a way so as to enable readers learn directly without the assistance of a classroom instructor. Throughout, there is an emphasis on presenting each new topic backed by real examples of a survival analysis investigation, followed up with thorough analyses of real data sets. Each chapter concludes with practice exercises to help readers reinforce their understanding of the concepts covered, before going on to a more comprehensive test. Answers to both are included. Readers will enjoy David Kleinbaums style of presentation, making this an excellent introduction for all those coming to the subject for the first time.
Author: Dirk F. Moore
Publisher: Springer
ISBN: 3319312456
Category : Medical
Languages : en
Pages : 245
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Book Description
Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Many survival methods are extensions of techniques used in linear regression and categorical data, while other aspects of this field are unique to survival data. This text employs numerous actual examples to illustrate survival curve estimation, comparison of survivals of different groups, proper accounting for censoring and truncation, model variable selection, and residual analysis. Because explaining survival analysis requires more advanced mathematics than many other statistical topics, this book is organized with basic concepts and most frequently used procedures covered in earlier chapters, with more advanced topics near the end and in the appendices. A background in basic linear regression and categorical data analysis, as well as a basic knowledge of calculus and the R system, will help the reader to fully appreciate the information presented. Examples are simple and straightforward while still illustrating key points, shedding light on the application of survival analysis in a way that is useful for graduate students, researchers, and practitioners in biostatistics.
Author: Joseph G. Ibrahim
Publisher: Springer Science & Business Media
ISBN: 1475734476
Category : Medical
Languages : en
Pages : 494
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Book Description
Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. It presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all from the health sciences, including cancer, AIDS, and the environment.
Author: John O'Quigley
Publisher: Springer Nature
ISBN: 3030334392
Category : Mathematics
Languages : en
Pages : 476
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Book Description
This book provides an extensive coverage of the methodology of survival analysis, ranging from introductory level material to deeper more advanced topics. The framework is that of proportional and non-proportional hazards models; a structure that is broad enough to enable the recovery of a large number of established results as well as to open the way to many new developments. The emphasis is on concepts and guiding principles, logical and graphical. Formal proofs of theorems, propositions and lemmas are gathered together at the end of each chapter separate from the main presentation. The intended audience includes academic statisticians, biostatisticians, epidemiologists and also researchers in these fields whose focus may be more on the applications than on the theory. The text could provide the basis for a two semester course on survival analysis and, with this goal in mind, each chapter includes a section with a range of exercises as a teaching aid for instructors.
Author: John P. Klein
Publisher: Springer Science & Business Media
ISBN: 1475727283
Category : Medical
Languages : en
Pages : 508
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Book Description
Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Author: David W. Hosmer, Jr.
Publisher: John Wiley & Sons
ISBN: 1118211588
Category : Mathematics
Languages : en
Pages : 285
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Book Description
THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.
Author: Odd Aalen
Publisher: Springer Science & Business Media
ISBN: 038768560X
Category : Mathematics
Languages : en
Pages : 550
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Book Description
The aim of this book is to bridge the gap between standard textbook models and a range of models where the dynamic structure of the data manifests itself fully. The common denominator of such models is stochastic processes. The authors show how counting processes, martingales, and stochastic integrals fit very nicely with censored data. Beginning with standard analyses such as Kaplan-Meier plots and Cox regression, the presentation progresses to the additive hazard model and recurrent event data. Stochastic processes are also used as natural models for individual frailty; they allow sensible interpretations of a number of surprising artifacts seen in population data. The stochastic process framework is naturally connected to causality. The authors show how dynamic path analyses can incorporate many modern causality ideas in a framework that takes the time aspect seriously. To make the material accessible to the reader, a large number of practical examples, mainly from medicine, are developed in detail. Stochastic processes are introduced in an intuitive and non-technical manner. The book is aimed at investigators who use event history methods and want a better understanding of the statistical concepts. It is suitable as a textbook for graduate courses in statistics and biostatistics.
Author: Andreas Wienke
Publisher: CRC Press
ISBN: 9781420073911
Category : Mathematics
Languages : en
Pages : 324
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Book Description
The concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals. Frailty Models in Survival Analysis presents a comprehensive overview of the fundamental approaches in the area of frailty models. The book extensively explores how univariate frailty models can represent unobserved heterogeneity. It also emphasizes correlated frailty models as extensions of univariate and shared frailty models. The author analyzes similarities and differences between frailty and copula models; discusses problems related to frailty models, such as tests for homogeneity; and describes parametric and semiparametric models using both frequentist and Bayesian approaches. He also shows how to apply the models to real data using the statistical packages of R, SAS, and Stata. The appendix provides the technical mathematical results used throughout. Written in nontechnical terms accessible to nonspecialists, this book explains the basic ideas in frailty modeling and statistical techniques, with a focus on real-world data application and interpretation of the results. By applying several models to the same data, it allows for the comparison of their advantages and limitations under varying model assumptions. The book also employs simulations to analyze the finite sample size performance of the models.
Author: John P. Klein
Publisher: CRC Press
ISBN: 146655567X
Category : Mathematics
Languages : en
Pages : 635
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Book Description
Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians
Author: Xian Liu
Publisher: John Wiley & Sons
ISBN: 1118307674
Category : Mathematics
Languages : en
Pages : 433
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Book Description
Survival analysis concerns sequential occurrences of events governed by probabilistic laws. Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis. Assumes only a minimal knowledge of SAS whilst enabling more experienced users to learn new techniques of data input and manipulation. Provides numerous examples of SAS code to illustrate each of the methods, along with step-by-step instructions to perform each technique. Highlights the strengths and limitations of each technique covered. Covering a wide scope of survival techniques and methods, from the introductory to the advanced, this book can be used as a useful reference book for planners, researchers, and professors who are working in settings involving various lifetime events. Scientists interested in survival analysis should find it a useful guidebook for the incorporation of survival data and methods into their projects.
