Malignant Pleural Mesothelioma PDF Download
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Author: Ken O'Byrne
Publisher:
ISBN: 0198529309
Category : Medical
Languages : en
Pages : 475
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Book Description
This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.
Author: Ken O'Byrne
Publisher:
ISBN: 0198529309
Category : Medical
Languages : en
Pages : 475
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Book Description
This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.
Author: Lung Cancer Disease Site Group
Publisher:
ISBN:
Category :
Languages : en
Pages : 46
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Book Description
Author: D. E. Maziak
Publisher:
ISBN:
Category :
Languages : en
Pages : 35
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Book Description
Author: Christoper Cao
Publisher:
ISBN:
Category : Mesothelioma
Languages : en
Pages :
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Book Description
Author: Cancer Care Ontario. Lung Cancer Disease Site Group
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 44
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Book Description
"Question: What is the role of surgery (pleurectomy or extrapleural pneumonectomy) in the treatment of adults with malignant pleural mesothelioma?"--Page 1.
Author: Giovanni Luca Ceresoli
Publisher: Springer
ISBN: 3030168840
Category : Medical
Languages : en
Pages : 341
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Book Description
This book offers an updated review of malignant mesothelioma, including the latest advances in our understanding of its genetic control and molecular biology, as well as pre-clinical and clinical research. It also presents state-of-the-art diagnostic approaches and therapeutic options, and an open discussion on the future prospects for patient management. Malignant mesothelioma is an enormous global health problem related to asbestos exposure. Despite the best efforts of scientists and oncologists, the prognosis for those affected remains poor. Due to anatomical characteristics and non-specific symptoms, the diagnosis of mesothelioma at an early stage is often difficult, while surgery and radiotherapy are only of limited use, even if some multimodality approaches seem promising. In turn, medical treatments are sometimes successful in tumor control, but have little impact on overall survival. However, advances in our understanding of the disease’s biology, together with the availability of new drugs and combinations, make mesothelioma an essential and highly topical field for pre-clinical and clinical studies. This book is subdivided into four parts: epidemiology and preclinical data, diagnosis, therapy, and extrathoracic mesothelioma. It highlights the progress made in a variety of areas – e.g. in vitro and in vivo experimental models, genetics, environment, biomarkers, targeting agents, immunotherapy, metabolic imaging and ongoing clinical trials – and describes the standard clinical management of mesothelioma patients, including those with extra-thoracic localizations. Given its scope, the book offers an invaluable tool for researchers, oncologists and clinicians alike.
Author:
Publisher:
ISBN:
Category : Lungs
Languages : en
Pages :
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Recommendations Because of the lack of sufficient high-quality evidence on the surgical management of mesothelioma, the Lung Cancer Disease Site Group opinion is that: • The role of surgery in the management of malignant pleural mesothelioma cannot be precisely defined. [...] Specifically, the lack of randomised controlled clinical trials makes it impossible to determine whether the use of extrapleural pneumonectomy or pleurectomy improves the survival of patients with malignant pleural mesothelioma or effectively palliates the symptoms of the disease. [...] Pleural fluid control improved in 98% of 50 patients and 96% of 54 patients; the recurrence of pleural effusion was prevented in 80% of 20 patients; dyspnea improved in 47% of 20 patients and 100% of 37 patients; and pain improved in 21% of 19 patients and 85% of 71 patients. [...] The former procedure generally involves the excision of sections of the pleura, and the latter, more aggressive approach involves the removal of all or part of a lung as well as the parietal pleura and ipsilateral pericardium and diaphragm. [...] Synthesizing the Evidence A statistical synthesis of the evidence was not conducted because no randomized trials involving surgical treatment for mesothelioma were identified and the prospective and retrospective studies included a variety of adjuvant treatments.
Author: Alice Bellini
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
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Book Description
Malignant pleural mesothelioma (MPM) is an aggressive malignancy with a poor prognosis, principally caused by a prior asbestos exposure. Up to the present, multimodality protocols including surgery with chemotherapy (CT) and/or radiotherapy (RT) represent the therapeutic gold standard for selected patients (epithelial and early-stage MPM). In this context, the aim of surgery is to accomplish the macroscopic complete resection (MCR). There are two main surgical options to obtain MCR,Äîextrapleural pneumonectomy (EPP) and pleurectomy/decortication (PD). The superiority of one surgical approach over the other is still discussed. To date, the decision to carry out one or the other in a multimodal setting is established on surgeons,Äô preference more than on strong scientific evidence. Due to the high morbidity, both surgical techniques should be achieved in tertiary referral centres. In summary, surgery, CT, and RT have failed as single modality therapies with no effects on patients survival. This aspect may be justified by the lack of randomized trials. Thus, novel therapeutic strategies, such as multimodality treatment and targeted agents, seem to prolong the survival and the quality of life. The aim of this chapter is to provide a complete overview of the current surgical approaches to MPM, discussing within the frameworks of pre-operative diagnostic evaluation and multimodality oncological treatments.
Author: Bryan M. Burt
Publisher: Elsevier Health Sciences
ISBN: 0323759653
Category : Medical
Languages : en
Pages : 137
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Book Description
This issue of Thoracic Surgery Clinics, guest edited by Dr. Bryan M. Burt, is devoted to Malignant Pleural Mesothelioma. Dr. Burt has assembled expert authors to review the following topics: Biomarkers for the Diagnosis and Monitoring of Malignant Pleural Mesothelioma; Taken Together: Effective Multimodal Approaches for Malignant Pleural Mesothelioma; Pleurectomy/Decortication for Malignant Pleural Mesothelioma; Preoperative Identification of Benefit from Surgery for Malignant Pleural Mesothelioma; The Role of Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma; The Molecular Basis of Malignant Pleural Mesothelioma; Radiation Therapy for Malignant Pleural Mesothelioma; The Staging of Malignant Pleural Mesothelioma; Intraoperative Adjuncts for Malignant Pleural Mesothelioma: The Fourth Dimension; The Pathology of Malignant Pleural Mesothelioma; and more!
