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Author: Yi Chen
Publisher: Springer Nature
ISBN: 9819931185
Category : Science
Languages : en
Pages : 391
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Book Description
This book introduces the fundamentals, instruments, methodology, and applications of surface plasmon resonance imaging (SPRi) and related techniques. It provides an overview of SPRi development and an easy-to-understand interpretation of theory and operation principles. Some unique ideas proposed by the authors to design and set up SPRi devices and methods are disclosed for the first time. Crucial manipulation experiences are also summarized here, including chip surface functionalization, sensitivity enhancement and coupling of SPRi with other analytical techniques. The application of SPRi for molecular interaction study, featuring high throughput, label-freeness, and physiologically compatible analysis, is discussed in detail. This book is of interest and useful to a wide readership in bioanalytical chemistry, molecular biology, and many related interdisciplinary fields.
Author: Yi Chen
Publisher: Springer Nature
ISBN: 9819931185
Category : Science
Languages : en
Pages : 391
Get Book Here
Book Description
This book introduces the fundamentals, instruments, methodology, and applications of surface plasmon resonance imaging (SPRi) and related techniques. It provides an overview of SPRi development and an easy-to-understand interpretation of theory and operation principles. Some unique ideas proposed by the authors to design and set up SPRi devices and methods are disclosed for the first time. Crucial manipulation experiences are also summarized here, including chip surface functionalization, sensitivity enhancement and coupling of SPRi with other analytical techniques. The application of SPRi for molecular interaction study, featuring high throughput, label-freeness, and physiologically compatible analysis, is discussed in detail. This book is of interest and useful to a wide readership in bioanalytical chemistry, molecular biology, and many related interdisciplinary fields.
Author: Richard B. M. Schasfoort
Publisher: Royal Society of Chemistry
ISBN: 1782627308
Category : Science
Languages : en
Pages : 555
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Book Description
Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.
Author: Richard B M Schasfoort
Publisher: Royal Society of Chemistry
ISBN: 1788011392
Category : Science
Languages : en
Pages : 555
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Book Description
Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events and with the biosensor field expanding more applications are being found. In response to the market, an update to the original title which was published in 2008 is now appropriate. With over fifty percent of the material being updated, this book provides a total system description including optics, fluidics and sensor surfaces. Spanning theory, instrumentation and applications, it covers all the relevant issues for the practicing researcher. Unlocking the potential for SPR by showing highly exciting and unique opportunities for unraveling the functional relationships of complex biological processes, it is intended for a wide audience. A comprehensive and accessible source it contains expanded tutorial details to inspire students and guide them in this technology.
Author:
Publisher: Elsevier
ISBN: 0323853102
Category : Science
Languages : en
Pages : 426
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Book Description
Surface Plasmon Resonance in Bioanalysis, Volume 95 in the Comprehensive Analytical Chemistry series, contains a wide range of topics on the applications and new advances of surface plasmon resonance (SPR) in bioanalysis, including Surface plasmon resonance microscopy for single-cell based drug screening, Phase-Sensitive Surface Plasmon Resonance Sensors for Highly Sensitive Bioanalysis, SPR coupled to ambient mass spectrometry, Surface Plasmon Resonance Microscopy for activity detection and imaging of single cells, SPR for water pollutant detection and biofouling control, SPR imaging for cellular analysis and detection, Progress in detection of surface palsmon resonance for biorefinery technology, and more. Additional chapters cover Long-range surface plasmon resonance and its biological sensing applications and Critical issues in clinical and biomedical applications of Surface Plasmon Resonance sensing. - Provides updates on the latest applications of SPR microscopy in cell analysis - Covers the latest design in SPR sensing for highly sensitive bioanalysis - Presents the critical issues in clinical and biomedical applications of SPR
Author: Roman Vander
Publisher:
ISBN:
Category :
Languages : en
Pages : 116
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Book Description
Author: Pranveer Singh
Publisher: Nova Science Publishers
ISBN: 9781633218352
Category : Plasmons (Physics)
Languages : en
Pages : 0
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Book Description
SPR is real-time, label-free measurements of binding kinetics and affinity. This has distinct advantage over radioactive or fluorescent labelling methods, in terms of: 1) ligand-analyte binding kinetics, that can be probed without the costly and time-consuming labeling process that may interfere with molecular binding interactions; 2) binding rates and affinity can be measured directly and 3) low affinity interactions in high protein concentrations for can be characterized with less reagent consumption than other equilibrium measurement techniques; 4) Label-free detection of molecular interactions presents an attractive alternative. This is particularly true for protein targets where labels can compromise protein function. Label-free methods are also desirable because they are typically compatible with real-time detection, enabling the determination of rates of association. The success of SPR biosensors was indicated by the growing number of commercially available instruments. Since Biacore AB (originally Pharmacia Biosensor AB) launched the first commercial SPR biosensor on market in 1990, there have been many more competing SPR instruments including IASys (Affinity Sensors), SPR-670 (Nippon Laser Electronics), IBIS (IBIS Technology BV), TISPR (Texas Instruments), etc.
Author: Kyle J. Foley
Publisher:
ISBN:
Category : Impedance (Electricity)
Languages : en
Pages : 178
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Book Description
Author: Yi-Tao Long
Publisher: Springer Science & Business Media
ISBN: 3642547958
Category : Science
Languages : en
Pages : 123
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Book Description
This book introduces the fundamentals and applications of the localized surface plasmon resonance (LSPR) property of noble metallic nanoparticles, with an emphasis on the biosensing applications of plasmonic nanoparticles, especially in living cell imaging and photothermal therapy. It provides an overview of the different operating principles of plasmonic sensors, particularly the single-nanoparticle-based detections, and a series of creative biosensors based on the modulation of different parameters of nanoparticles (particle size, shape, composition and surrounding medium) for label-free detection. The interparticle coupling effect, plasmon resonance energy transfer, electron transfer on plasmonics surface are also covered in this book. This book is intended for graduate students and researchers working in the interdisciplinary field combining chemistry, biology, material science and nanophotonics. Yi-Tao Long is a Professor at the School of Chemistry and Molecular Engineering, East China University of Science and Technology, China.
Author: Mary S. Golden
Publisher:
ISBN:
Category :
Languages : en
Pages : 450
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Book Description
Author: Eric Le Ru
Publisher: Elsevier
ISBN: 0080931553
Category : Science
Languages : en
Pages : 688
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Book Description
SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. - Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) - Gives a comprehensive summary of the underlying physical concepts around SERS - Provides a detailed analysis of plasmons and plasmonics
