Studies of Dentin Matrix Protein 1 (DMP1) Regulation and Function in Vivo PDF Download
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Author: Yongbo Lu
Publisher:
ISBN: 9780549000600
Category : Bone cells
Languages : en
Pages : 124
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Book Description
Dentin matrix protein 1 (DMP1) is a highly phosphorylated extracellular matrix protein, predominantly expressed in osteocytes in bone. Full-length DMP1 is enzymatically processed into a 37 kDa N- and a 57 kDa C-terminal fragment in vivo. The goal of this study was to identify the cis-regulatory regions that control osteoctye-specific expression of the DMP1 gene, to determine the in vivo function of the 57 kDa C-terminal fragment and to determine the role of DMP1 in control of phosphate homeostasis.
Author: Yongbo Lu
Publisher:
ISBN: 9780549000600
Category : Bone cells
Languages : en
Pages : 124
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Book Description
Dentin matrix protein 1 (DMP1) is a highly phosphorylated extracellular matrix protein, predominantly expressed in osteocytes in bone. Full-length DMP1 is enzymatically processed into a 37 kDa N- and a 57 kDa C-terminal fragment in vivo. The goal of this study was to identify the cis-regulatory regions that control osteoctye-specific expression of the DMP1 gene, to determine the in vivo function of the 57 kDa C-terminal fragment and to determine the role of DMP1 in control of phosphate homeostasis.
Author: Dayong Guo
Publisher:
ISBN:
Category :
Languages : en
Pages : 104
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Book Description
Author: Wuchen Yang
Publisher:
ISBN:
Category : Bone cells
Languages : en
Pages : 252
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Book Description
Author: Michel Goldberg
Publisher: Bentham Science Publishers
ISBN: 1608054659
Category : Medical
Languages : en
Pages : 464
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Book Description
Phosphorylated Extracellular Matrix Proteins of Bone and Dentin is the second volume of the e-book series Frontiers between Science and Clinic in Odontology. The phosphorylated proteins of the extracellular matrix of bone and teeth play a crucial structural role in the two tissues. They also act as signaling molecules. Phosphorylated extracellular matrix proteins have been implicated in nucleation and mineralization of skeletal tissues. This e-book covers research on these specific proteins, including details about the cells producing these molecules, their impact on bone and teeth pathology (osteogenesis and dentinogenesis imperfecta) and the potential of these molecules in promoting of inhibiting mineralization. This e-book also explains processes under the control of some enzymes - TNAP and metalloproteases (MMPs) - such as intracellular regulation in bone and dentine, splicing, respective roles of cleavage products, SIBLINGs, nucleation and crystal growth and regulation. This second volume serves as a valuable reference to practicing odontologists, biology and biomaterials scientists and tissue engineers interested in protein research related to tooth and bone formation.
Author: Abdullah S. Almushayt
Publisher:
ISBN:
Category :
Languages : en
Pages : 246
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Book Description
Author: Peter D. Yurchenco
Publisher: Academic Press
ISBN: 1483289427
Category : Science
Languages : en
Pages : 483
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Book Description
The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Addresses assembly of most of the known classes of extracellular matrix macromolecules Discusses higher order structures produced by ECM Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling
Author: Gregory H. Hudalla
Publisher: Royal Society of Chemistry
ISBN: 1849738335
Category : Medical
Languages : en
Pages : 422
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Book Description
Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.
Author: Ramesh S. Chaughule
Publisher: Springer Nature
ISBN: 3030522075
Category : Technology & Engineering
Languages : en
Pages : 410
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Book Description
As the name suggests this book discusses how nanotechnology has influenced the provision of implant treatment from surgery to prosthetic reconstruction and post treatment biological complications. This book is a sequel to the earlier book “Dental Applications of Nanotechnology” published by Springer. It aims to present both the nanotechnology and allied research along with the clinical concepts of almost every different aspect of implantology in one volume. These two fraternities promote the translation of the research ideas and product development into fruitful practicalities. The first section covers nanobiomaterials in implant applications, in bone regeneration, prosthetic rehabilitation, to control biofilm and peri-implantitis, bone grafting and tissue engineering. The second section explores applications of such new technologies in the field of implantology that gives this book a unique feature by bringing science and technology into clinical application. It covers implant stability, peri-implantitis, lasers, CAD/CAM technology, impressions, 3D printing, reconstruction with bone grafts and zygomatic implants. Comprehensive coverage includes both simple and complicated clinical cases, with practical guidance on how to apply the latest research, diagnostic tools, treatment planning, implant designs, materials, and techniques to provide superior patient outcomes. The book is well written and structured making it easy for experienced clinicians and those new to dental implantology as well as students, researchers, scientists and faculties of dental universities
Author: Francis H. Glorieux
Publisher: Academic Press
ISBN: 0123820405
Category : Medical
Languages : en
Pages : 885
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Book Description
Pediatric osteology, a medical specialty that has come of age, has contributed to the understanding of adult bone diseases as well. This second edition reference updates the 2003 edition with more emphasis on management as well as new and revised contributions. Thirty chapters present basic information regarding bone development, tools and techniques for evaluation (including a new chapter on radiographic imaging), and the specifics of various diseases. The three editors are affiliated as follows: Francis H. Glorieux (McGill U., Canada), John M. Pettifor (Chir Hani Baragwanath Hospital, South Africa), and Harald Juppner (Harvard Medical School, US). Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).
Author: David B. Burr
Publisher: Academic Press
ISBN: 0123914590
Category : Science
Languages : en
Pages : 390
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Book Description
This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. Presents an in-depth overview of skeletal biology from the molecular to the organ level Offers "refresher" level content for clinicians or researchers outside their areas of expertise Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology
