Structure, Dynamics, and Biogenesis of Biomembranes

Structure, Dynamics, and Biogenesis of Biomembranes PDF Author: Ryo Sato
Publisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 196

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Book Description
Biomembranes are not only principal constituents of the cell but also a major site of biological activity. Studies on biomembranes are therefore, crucial for furthering our understanding of life processes. A special research project on biomembranes involving more than 100 in vestigators was conducted under a grant from the Ministry of Education, Science and Culture of Japan between 1978 and 1981. This has resulted in marked progress on basic biomedical studies on biomembranes in Japan. This book is a compilation of several major developments made during this project in the field of "Structure, Dynamics, and Biogenesis of Biomembranes. " Developments in other fields constitute the contents of a companion volume, "Transport and Bioenergetics in Biomembranes," edited by Sato and Kagawa. In these two volumes the authors review recent advances which have been primarily made in their own labora tories and include relevant work carried out by other investigators. Eight topics are presented in this volume. Ikegami and coworkers review molecular dynamics in lipid bilayers, reconstituted membranes and biological membranes as studied by nanosecond fluorescence spec troscopy with an emphasis on the wobbling in the cone model. The fol lowing two chapters deal with virus-induced membrane fusions. Ohnishi and Maeda describe an assay method for envelope fusion using spin labeled phospholipids and report several characteristic results obtained by this method including low pH-induced fusion of influenza virus.

Structure, Dynamics, and Biogenesis of Biomembranes

Structure, Dynamics, and Biogenesis of Biomembranes PDF Author: Ryo Sato
Publisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 196

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Book Description
Biomembranes are not only principal constituents of the cell but also a major site of biological activity. Studies on biomembranes are therefore, crucial for furthering our understanding of life processes. A special research project on biomembranes involving more than 100 in vestigators was conducted under a grant from the Ministry of Education, Science and Culture of Japan between 1978 and 1981. This has resulted in marked progress on basic biomedical studies on biomembranes in Japan. This book is a compilation of several major developments made during this project in the field of "Structure, Dynamics, and Biogenesis of Biomembranes. " Developments in other fields constitute the contents of a companion volume, "Transport and Bioenergetics in Biomembranes," edited by Sato and Kagawa. In these two volumes the authors review recent advances which have been primarily made in their own labora tories and include relevant work carried out by other investigators. Eight topics are presented in this volume. Ikegami and coworkers review molecular dynamics in lipid bilayers, reconstituted membranes and biological membranes as studied by nanosecond fluorescence spec troscopy with an emphasis on the wobbling in the cone model. The fol lowing two chapters deal with virus-induced membrane fusions. Ohnishi and Maeda describe an assay method for envelope fusion using spin labeled phospholipids and report several characteristic results obtained by this method including low pH-induced fusion of influenza virus.

Biological Membranes: Structure, Biogenesis and Dynamics

Biological Membranes: Structure, Biogenesis and Dynamics PDF Author: Jos A.F. Op den Kamp
Publisher: Springer Science & Business Media
ISBN: 3642788467
Category : Science
Languages : en
Pages : 358

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Book Description
The Advanced Study Institute on "Structure, Biogenesis and Dynamics of Biological Membranes, held in Cargese from June 14-26, 1993, has been dealing with four major topics in membrane biochemistry today: lipid dynamics and lipid-protein interactions, protein translocation and insertion, intracellular traffic aud protein structure and folding. The lecturers discussed these topics starting from several disciplines, including biochemistry, cell biology, genetics, and biophysics. This wayan interdisciplinary and very inte~sting view on biological membrane systems was obtained. At first an extensive overview of -mainly biophysical -techniques which can be used to study dynamic processes in membranes was presented. Sophisticated approaches such as ESR and NMR have been applied succesfully to unravel details of specific lipid-protein interactions. x ray analysis provides detailed structural information of several proteins and the possible implications for protein functions. Information obtained this way is complemented by studies on mechanisms and kinetics of protein folding. The latter information is indispensable when discussing protein translocation and insertion: proces:;es in which folding and unfolding play essential roles. Extensive insight was offered in the complicated machinery of phospholipid biosynthesis. In particular, the application of sophisticated genetic techniques has allowed a better understanding of the mechanisms regulating the synthetic machinery and detailed studies on a variety of mutants, lacking one or more of the essential enzymes, have resulted in the beginning of a bL!:

Dynamics and Biogenesis of Membranes

Dynamics and Biogenesis of Membranes PDF Author: Josef A.F. Op den Kamp
Publisher: Springer Science & Business Media
ISBN: 3642741940
Category : Science
Languages : en
Pages : 367

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Book Description
Membrane proteins, lipids and their glycosylated derivatives are discussed both with respect to their biosynthesis as well as regarding their mutual interaction and assembly into functional membranes. Topics cover a large variety of systems and cells: investigation on virus membranes as well as pro- and eukaryotic cells are included.

Structure and Dynamics of Membranes

Structure and Dynamics of Membranes PDF Author: R. Lipowsky
Publisher: Elsevier
ISBN: 0080541917
Category : Technology & Engineering
Languages : en
Pages : 537

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Book Description
The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Structure and Dynamics of Membranes

Structure and Dynamics of Membranes PDF Author: R. Lipowsky
Publisher: North Holland
ISBN: 9780444819758
Category : Technology & Engineering
Languages : en
Pages : 1052

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Book Description
The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateral phase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes with polymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process of contact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned about the interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Membrane Biogenesis

Membrane Biogenesis PDF Author: Jos A.F. Op den Kamp
Publisher: Springer
ISBN: 9783540185666
Category : Science
Languages : en
Pages : 477

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Book Description
Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Biomembranes

Biomembranes PDF Author: Robert B. Gennis
Publisher: Springer Science & Business Media
ISBN: 1475720653
Category : Science
Languages : en
Pages : 549

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Book Description
New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses.

Structure, Dynamics, and Biogenesis of Biomembranes

Structure, Dynamics, and Biogenesis of Biomembranes PDF Author: 佐藤了
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 196

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Book Description


The Structure of Biological Membranes

The Structure of Biological Membranes PDF Author: Philip L. Yeagle
Publisher: CRC Press
ISBN: 1439809585
Category : Medical
Languages : en
Pages : 398

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Book Description
Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro

Fluorescence Studies on Biological Membranes

Fluorescence Studies on Biological Membranes PDF Author: Herwig J. Hilderson
Publisher: Springer Science & Business Media
ISBN: 1461393590
Category : Science
Languages : en
Pages : 480

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Book Description
As stated by its first editor, Dr. D. B. Roodyn, the primary goal of the series Subcellular Biochemistry is to achieve an integrated view of the cell by bringing together results from a wide range of different techniques and disciplines. This volume deals with the applications of fluorescence spectroscopy to membrane research. It seeks to present complementary biochemical and bio physical data on both the structure and the dynamics of biological membranes. Biophysics and biochemistry are improving more and more in their ability to study biomembranes, overlapping somewhat in this area and explaining the functioning of the whole cell in terms of the properties of its individual com ponents. Therefore, we have brought together an international group of experts in order to report on and review advances in fluorescence studies on biological membranes, thereby highlighting subcellular aspects. The first chapters present a critical evaluation of the current applications of dynamic and steady-state fluorescence techniques. Subsequent chapters dis cuss more specific applications in cells, biological membranes, and their con stituents (lipids, proteins).