Author: Albert Gossauer
Publisher: John Wiley & Sons
ISBN: 3906390721
Category : Science
Languages : en
Pages : 683
Get Book Here
Book Description
All the material needed for a modern course in organic chemistry, designed to interconnect biology and chemistry and facilitate communication between the two disciplines. Adopting a novel approach, this textbook explains the structure and reactivity of organic molecules along with simple chemical reaction mechanisms pertinent to cell metabolism, with assignments and corresponding answers for self-study in every chapter. In addition, biologically relevant substances and enzymatic reactions are described, building a bridge to biology. As opposed to textbooks in biochemistry, this book considers both primary metabolites, including their prebiotic formation, as well as important nutrients. Alongside the detailed nomenclature and etymology of the scientific terms, examples of natural and artificial products provide an insight into the wide range of materials found in everyday life, whetting the readers` appetite for a deeper study of the chemistry of biological processes. Finally, the biographies of over one hundred famous scientists illustrate the major achievements of chemistry and biology in the 20th century.
Author: Kevin Naidoo
Publisher: Royal Society of Chemistry
ISBN: 1847555373
Category : Science
Languages : en
Pages : 305
Get Book Here
Book Description
Computational and theoretical tools for understanding biological processes at the molecular level is an exciting and innovative area of science. Using these methods to study the structure, dynamics and reactivity of biomacromolecules in solution, computational chemistry is becoming an essential tool, complementing the more traditional methods for structure and reactivity determination. Modelling Molecular Structure and Reactivity in Biological Systems covers three main areas in computational chemistry; structure (conformational and electronic), reactivity and design. Initial sections focus on the link between computational and spectroscopic methods in the investigation of electronic structure. The use of Free Energy calculations for the elucidation of reaction mechanisms in enzymatic systems is also discussed. Subsequent sections focus on drug design and the use of database methods to determine ADME (absorption, distribution, metabolism, excretion) properties. This book provides a complete reference on state of the art computational chemistry practised on biological systems. It is ideal for researchers in the field of computational chemistry interested in its application to biological systems.
Author: John J. Stezowski
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 650
Get Book Here
Book Description
This volume draws together contributions from many areas of research aimed at understanding chemical reactivity and biological activity in terms of molecular structure. It provides an overview of numerous areas of current work and demonstrates the many common interests shared by investigators in this area, among them mineralogists, chemists, biologists, and physicists.
Author: Robert Austin
Publisher: Springer
ISBN: 1461247969
Category : Science
Languages : en
Pages : 515
Get Book Here
Book Description
This book is concerned with the physical aspects of molecular and electronic tunneling in biological systems, and the extent to which protein structure controls these events. The scope is very broad and this volume could almost be a textbook in biophysics. Both fundamental processes and the extrapolation to physiological events are stressed. The discussion sections are remarkably frank and offer insight into the basic problems confronting physists and chemists as they seek to apply their techniques to biological systems. This book on the physics of biomolecules reflects recent progress in understanding the biological function of the key protein molecules from detailed knowledge of their physics. New and exciting are the glasslike aspects of protein structures and the discussion of proteins as fractals. Other topics dealt with are low-temperature kinetics and reactivity, structure and charge exchange, and charge separation in photosynthetic reaction centers.
Author: Samantha Fowler
Publisher:
ISBN: 9781739015503
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Chava Lifshitz
Publisher: John Wiley & Sons
ISBN: 0470050411
Category : Science
Languages : en
Pages : 707
Get Book Here
Book Description
An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques.
Author: Gerhard Klebe
Publisher: Springer
ISBN: 9783642179068
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.
Author: G. Vergoten
Publisher: Springer Science & Business Media
ISBN: 9401154848
Category : Science
Languages : en
Pages : 327
Get Book Here
Book Description
Biomolecular Structure and Dynamics describes recent fundamental advances in the experimental and theoretical study of molecular dynamics and stochastic dynamic simulations, X-ray crystallography and NMR of biomolecules, the structure of proteins and its prediction, time resolved Fourier transform IR spectroscopy of biomolecules, the computation of free energy, applications of vibrational CD of nucleic acids, and solid state NMR. Further presentations include recent advances in UV resonance Raman spectroscopy of biomolecules, semiempirical MO methods, empirical force fields, quantitative studies of the structure of proteins in water by Fourier transform IR, and density functional theory. Metal-ligand interactions, DFT treatment of organometallic and biological systems, and simulation vs. X-ray and far IR experiments are also discussed in some detail. The book provides a broad perspective of the current theoretical aspects and recent experimental findings in the field of biomolecular dynamics, revealing future research trends, especially in areas where theoreticians and experimentalists could fruitfully collaborate.
Author: Anders Ehrenberg
Publisher: Springer Science & Business Media
ISBN: 3642717055
Category : Science
Languages : en
Pages : 316
Get Book Here
Book Description
This is a collection of papers presented and discussed at the first EBSA workshop held at Saltsj6baden outside stockholm in Sweden, July 6-10, 1986. The common theme of these papers is dynamics of biomolecules, and how the dynamics depends on the molecular structure and organi zation, and connects to and determines the biological function. This is a rapidly expanding field of research which combines many different aspects of molecular bio physics. Much material is new and presented for the first time. Even if the work so far has been of the kind that is usually called basic research, practical applications are clearly indicated in some articles, and are waiting around the corner in several other cases. At the workshop only one third of the time was used for the formal presentations and two thirds for discussion. To this should also be added discussions during the poster sessions. During these lively and unrecorded discussions fresh viewpoints emerged and new ideas were created. Ad mittedly, our knowledge at present is only fragmentary but when pieces of the puzzle are brought together at a workshop or in a publication of this kind more extended and sometimes unexpected contours and shapes become vi sible. It is our hope that this rapid publication of camera-ready manuscripts will transfer some of the spi rit at the workshop to the reader, and in his or her institute or laboratory initiate further discussions, bring forward more ideas and start new experimental ap roaches.
