Still Missing

Still Missing PDF Author: Chevy Stevens
Publisher: ReadHowYouWant.com
ISBN: 1459612965
Category : Fiction
Languages : en
Pages : 410

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Book Description
Grim and unsettling ... a fast-paced read that is utterly absorbing.' - Kathy Reichs On the day she was abducted, Annie O'Sullivan, a 32-year-old real estate agent, had three goals - sell a house, forget about a recent argument with her mother, and be on time for dinner with her ever-patient boyfriend. The open house is slow, but when her last v...

Still Missing

Still Missing PDF Author: Chevy Stevens
Publisher: ReadHowYouWant.com
ISBN: 1459612965
Category : Fiction
Languages : en
Pages : 410

Get Book Here

Book Description
Grim and unsettling ... a fast-paced read that is utterly absorbing.' - Kathy Reichs On the day she was abducted, Annie O'Sullivan, a 32-year-old real estate agent, had three goals - sell a house, forget about a recent argument with her mother, and be on time for dinner with her ever-patient boyfriend. The open house is slow, but when her last v...

The Ischemic Penumbra: Still the Target for Stroke Therapies?

The Ischemic Penumbra: Still the Target for Stroke Therapies? PDF Author: Argye E. Hillis
Publisher: Frontiers Media SA
ISBN: 2889196356
Category : Acute ischemic stroke
Languages : en
Pages : 71

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Book Description
The ischemic penumbra was initially defined by Symon, Lassen and colleagues in the 1970s as an area of brain tissue with inadequate blood flow to maintain electric activity of neurons but adequate blood flow to preserve the function of the ion channels. This area of tissue, receiving enough blood to survive but not enough to function, often surrounds or abuts the irreversibly damaged core in ischemic stroke. It was shown that if blood flow could be restored to this area of marginal perfusion, the tissue could survive and function again, and growth of the core could be prevented. Based on seminal PET studies, penumbra or "penumbral tissue" eventually took on a subtly different meaning - the area of brain that is destined to progress to infarct unless blood flow is restored within a particular time window. The penumbra thus became the target for all acute stroke interventions - to preserve viability of the tissue and restore function. New imaging techniques, including diffusion and perfusion MRI and CT perfusion, were developed to rapidly identify individuals with penumbra, who were thought to be the best candidates for aggressive interventions to restore blood flow, particularly beyond the licensed time-window for IV thrombolysis. However, most clinical trials have failed to establish the usefulness of identifying candidates for treatment in this way using pre-specified protocols and primary endpoints. These trials have used different and sometimes unvalidated thresholds of hypoperfusion as well as irreversible infarct and various definitions of significant penumbra (or mismatch between irreversible infarct and hypoperfused, but salvageable tissue), and reanalysis of their data using more refined image processing showed post-hoc positivity. They have also evaluated outcome in a variety of ways, with few studies measuring the direct effect of restoring blood flow on the function of the penumbral tissue. Therefore, important remaining questions include how to define, characterize, and image the penumbra in acute stroke to achieve the greatest reliability and validity for what we want to measure, and whether this concept, so defined, provides an optimal target for stroke therapy using state-of-the-art trial design.

A World Made for Money

A World Made for Money PDF Author: Bret Wallach
Publisher: U of Nebraska Press
ISBN: 080329896X
Category : Business & Economics
Languages : en
Pages : 489

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Book Description
A spirited and incisive survey of economic geography, A World Made for Money begins with the author stopped at a red light in Norman, Oklahoma. Observing the landscape of drugstores and banks, and for that matter the stoplight and roads themselves, Bret Wallach observes, “Everything I see has been built to make money” or, at the very least, to facilitate making money. This, he argues, is a global phenomenon that nonetheless has occurred only within the past hundred years or so. Although guidebooks and culture brokers often disparage these landscapes of commerce, Wallach—recipient of a MacArthur “genius grant”—argues that we would do well to pay them close attention. A World Made for Money provides a compelling, condensed tour of our world. From Silicon Valley to Sri Lanka, from post-Soviet Russia to post-apartheid South Africa, Wallach looks at how human beings are buying, manufacturing, working, growing and shipping food, and accessing the natural resources to fuel it all. These essential facets of daily life, propelled by the profit motive, represent a transnational force shaping our surroundings and environment in ways that may not always be beautiful (or even healthy) but that are fundamental to understanding how the world works in the twenty-first century. Wallach examines the relationship between acquisitiveness and landscape, reveals surprising contradictions and nuances, and provides fresh perspective on politically charged topics such as sprawl, deindustrialization, and agribusiness.

Targets of Revenge

Targets of Revenge PDF Author: Jeffrey S. Stephens
Publisher: Simon and Schuster
ISBN: 1451688741
Category : Fiction
Languages : en
Pages : 544

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Book Description
"All the bureaucratic scolding in Washington cannot stop resourceful CIA Agent Jordan Sandor when he's hungry for revenge"--Publisher description.

Trap Shooting Secrets

Trap Shooting Secrets PDF Author: James Russell
Publisher: James Russell Publishing
ISBN: 0916367096
Category : Sports & Recreation
Languages : en
Pages : 190

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Book Description
With over 132 practice tips and more than 100 illustrations, reading this guide is like having a personal shooting coach. This huge technical book teaches techniques of professional trap shooting; singles, handicap and double trap.

Brenner and Rector's The Kidney E-Book

Brenner and Rector's The Kidney E-Book PDF Author: Alan S. L. Yu
Publisher: Elsevier Health Sciences
ISBN: 0323262597
Category : Medical
Languages : en
Pages : 3585

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Book Description
Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification. Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations. Uniform terminology and nomenclature in line with emerging consensus in world kidney community. More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information. Internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors . An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields. The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.

Ramblings of a Targeted Individual (Sixth Edition)

Ramblings of a Targeted Individual (Sixth Edition) PDF Author: Sharon R. Poet
Publisher: Createspace Independent Pub
ISBN: 9781503106024
Category : Technology & Engineering
Languages : en
Pages : 420

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Book Description
A Targeted Individual's painful fight to expose criminal use of satellite surveillance systems and radio wave technologies as well as covert harassment programs. My work has become a fight to regain my freedom from covert targeting so that I can recover and do what I was born to be doing with my life. Please become aware and help bring an end to this crisis. www.targetedinamerica.com

Water and Liberalisation

Water and Liberalisation PDF Author: Matthias Finger
Publisher: IWA Publishing
ISBN: 1843391139
Category : Science
Languages : en
Pages : 238

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Book Description
In most network industries, new dynamics are leading to an unprecedented opening up to competition and private sector participation. With the development of a single European market, the in-stages liberalisation process of public utilities has spread to almost all sectors. However, the water supply and sanitation (WSS) sector is considered somehow different and it has been excluded until recently from the restructuring processes achieved in other sectors. Water and Liberalisation: European Water Scenarios presents a better understanding of the specific demands of the WSS sector. Covering the operators' strategies, the regulatory dynamics as well as their interactions on the evolution of the sector, it addresses the likelihood, the nature, and the forms the WSS sector may take in Europe in the foreseeable future. Adopting a neutral political stance, the book analyses the implications of alternative scenarios in economic, ecological, social, legal, and institutional terms. Key sections include: In depth introduction to the current situation in the WSS sector; The European water supply and sanitation markets; The institutional framework of the water supply and sanitation sector in the EU: a comparative analysis; Analysis of the EU explicit and implicit policies and approaches in the sector; Analysis of the strategies of the water operators in Europe scenarios on the evolution of the water sector in Europe; Economic, environmental, & social implications of the scenarios; Major implications per scenario.

The Success of Sanctions

The Success of Sanctions PDF Author: Francesco Giumelli
Publisher: Routledge
ISBN: 1317014642
Category : Political Science
Languages : en
Pages : 265

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Book Description
The effectiveness of sanctions cannot purely be measured by the way they change the behaviour of their intended target. The degree to which sanctions constrain a rogue state's behaviour and the signals they send to future targets should also be prime considerations. In this thought provoking book Francesco Giumelli measures the true effectiveness of EU sanctions against a range of states including Belarus, Zimbabwe, Moldova, Uzbekistan, the USA and China. He demonstrates that focussing purely on behavioural change is limiting, especially when considering the actions and motivations of an international organisation, and develops a process to evaluate the direct and indirect impact of EU sanctions. Giumelli demonstrates the many different ways sanctions have been used by the EU to produce positive direct and indirect results and provides a multi-level framework to assess the success of sanctions in the future.

Willing Target

Willing Target PDF Author: Kathleen Mix
Publisher: Entangled: Select Suspense
ISBN: 163375751X
Category : Fiction
Languages : en
Pages : 336

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Book Description
The last thing covert operative Mitch Weaver wants is to be partnered with a gorgeous, reckless newbie. Still reeling from the death of his former partner, Mitch doesn't need the responsibility of keeping anyone else alive, especially when they volunteer to be a killer's target. Not to mention, his attraction to the too-perky blonde is the kind of distraction that could get them both killed in their line of work. Andrea Carnegie's first assignment isn't going quite as she planned. Her partner might be sexy but he's completely frustrating with his determination to keep her out of danger. Masquerading as a billionaire's sister to bait a possible killer is her chance to shine. But if she wants to catch the person threatening their client, she’ll have to find a way to work together with Mitch while still keeping her distance. Even as the air between them sizzles, Andrea knows the worst possible thing she could do is fall for her partner.