Author: G.Naray- Naray-Szabo
Publisher: CRC Press
ISBN: 1351085344
Category : Science
Languages : en
Pages : 273
Book Description
The present volume deals with the application of the following techniques; computational chemistry, X-ray diffraction, and two-dimensional nuclear magnetic resonance. The book will discuss how these methods can be used to study steric aspects of biomolecular interactions.
Steric Aspects Of Biomolecular Interactions
Author: G.Naray- Naray-Szabo
Publisher: CRC Press
ISBN: 1351085344
Category : Science
Languages : en
Pages : 273
Book Description
The present volume deals with the application of the following techniques; computational chemistry, X-ray diffraction, and two-dimensional nuclear magnetic resonance. The book will discuss how these methods can be used to study steric aspects of biomolecular interactions.
Publisher: CRC Press
ISBN: 1351085344
Category : Science
Languages : en
Pages : 273
Book Description
The present volume deals with the application of the following techniques; computational chemistry, X-ray diffraction, and two-dimensional nuclear magnetic resonance. The book will discuss how these methods can be used to study steric aspects of biomolecular interactions.
Molecular Aspects of Biotechnology: Computational Models and Theories
Author: Juan Bertrán
Publisher: Springer Science & Business Media
ISBN: 9401125384
Category : Science
Languages : en
Pages : 343
Book Description
Although biotechnology emerged from the genetic engineering revolution of the '70s, the knowledge of the structure of genes revealed its molecular aspects. Molecular biotechnology is a multidisciplinary domain of research in which experiments, simulations, and theories interact. At present, the huge increase in computer power allows us to carry out numerical simulations of biochemical systems. However, a fundamental question appears concerning the sophistication of the model utilized to capture the main features of biomolecules and biochemical processes. In the present book a group of leading specialists in molecular biotechnology provides an answer to this question. This book is thus an excellent tool for those researchers wishing to know the state-of-the-art in this domain. The book spans the range from molecular conformations through protein folding, and from chemical reactivity through enzymatic action. Furthermore, it formulates recommendations for future research in molecular biotechnology.
Publisher: Springer Science & Business Media
ISBN: 9401125384
Category : Science
Languages : en
Pages : 343
Book Description
Although biotechnology emerged from the genetic engineering revolution of the '70s, the knowledge of the structure of genes revealed its molecular aspects. Molecular biotechnology is a multidisciplinary domain of research in which experiments, simulations, and theories interact. At present, the huge increase in computer power allows us to carry out numerical simulations of biochemical systems. However, a fundamental question appears concerning the sophistication of the model utilized to capture the main features of biomolecules and biochemical processes. In the present book a group of leading specialists in molecular biotechnology provides an answer to this question. This book is thus an excellent tool for those researchers wishing to know the state-of-the-art in this domain. The book spans the range from molecular conformations through protein folding, and from chemical reactivity through enzymatic action. Furthermore, it formulates recommendations for future research in molecular biotechnology.
NIDA Research Monograph
Author:
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 592
Book Description
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 592
Book Description
Current Catalog
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1060
Book Description
First multi-year cumulation covers six years: 1965-70.
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1060
Book Description
First multi-year cumulation covers six years: 1965-70.
Computational Approaches to Biochemical Reactivity
Author: Gábor Náray-Szabó
Publisher: Springer Science & Business Media
ISBN: 9781402004155
Category : Science
Languages : en
Pages : 396
Book Description
A quantitative description of the action of enzymes and other biological systems is both a challenge and a fundamental requirement for further progress in our und- standing of biochemical processes. This can help in practical design of new drugs and in the development of artificial enzymes as well as in fundamental understanding of the factors that control the activity of biological systems. Structural and biochemical st- ies have yielded major insights about the action of biological molecules and the mechanism of enzymatic reactions. However it is not entirely clear how to use this - portant information in a consistent and quantitative analysis of the factors that are - sponsible for rate acceleration in enzyme active sites. The problem is associated with the fact that reaction rates are determined by energetics (i. e. activation energies) and the available experimental methods by themselves cannot provide a correlation - tween structure and energy. Even mutations of specific active site residues, which are extremely useful, cannot tell us about the totality of the interaction between the active site and the substrate. In fact, short of inventing experiments that allow one to measure the forces in enzyme active sites it is hard to see how can one use a direct experimental approach to unambiguously correlate the structure and function of enzymes. In fact, in view of the complexity of biological systems it seems that only computers can handle the task of providing a quantitative structure-function correlation.
Publisher: Springer Science & Business Media
ISBN: 9781402004155
Category : Science
Languages : en
Pages : 396
Book Description
A quantitative description of the action of enzymes and other biological systems is both a challenge and a fundamental requirement for further progress in our und- standing of biochemical processes. This can help in practical design of new drugs and in the development of artificial enzymes as well as in fundamental understanding of the factors that control the activity of biological systems. Structural and biochemical st- ies have yielded major insights about the action of biological molecules and the mechanism of enzymatic reactions. However it is not entirely clear how to use this - portant information in a consistent and quantitative analysis of the factors that are - sponsible for rate acceleration in enzyme active sites. The problem is associated with the fact that reaction rates are determined by energetics (i. e. activation energies) and the available experimental methods by themselves cannot provide a correlation - tween structure and energy. Even mutations of specific active site residues, which are extremely useful, cannot tell us about the totality of the interaction between the active site and the substrate. In fact, short of inventing experiments that allow one to measure the forces in enzyme active sites it is hard to see how can one use a direct experimental approach to unambiguously correlate the structure and function of enzymes. In fact, in view of the complexity of biological systems it seems that only computers can handle the task of providing a quantitative structure-function correlation.
NASA Technical Memorandum
Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 468
Book Description
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 468
Book Description
Molecules in Physics, Chemistry, and Biology
Author: J. Maruani
Publisher: Springer Science & Business Media
ISBN: 9400928491
Category : Science
Languages : en
Pages : 266
Book Description
Volume 1: General Introduction to Molecular Sciences Volume 2: Physical Aspects of Molecular Systems Volume 3: Electronic Structure and Chemical Reactivity Volume 4: Molecular Phenomena in Biological Sciences
Publisher: Springer Science & Business Media
ISBN: 9400928491
Category : Science
Languages : en
Pages : 266
Book Description
Volume 1: General Introduction to Molecular Sciences Volume 2: Physical Aspects of Molecular Systems Volume 3: Electronic Structure and Chemical Reactivity Volume 4: Molecular Phenomena in Biological Sciences
Molecular Interactions
Author: Aurelia Meghea
Publisher: BoD – Books on Demand
ISBN: 9535100793
Category : Medical
Languages : en
Pages : 386
Book Description
In a classical approach materials science is mainly dealing with interatomic interactions within molecules, without paying much interest on weak intermolecular interactions. However, the variety of structures actually is the result of weak ordering because of noncovalent interactions. Indeed, for self-assembly to be possible in soft materials, it is evident that forces between molecules must be much weaker than covalent bonds between the atoms of a molecule. The weak intermolecular interactions responsible for molecular ordering in soft materials include hydrogen bonds, coordination bonds in ligands and complexes, ionic and dipolar interactions, van der Waals forces, and hydrophobic interactions. Recent evolutions in nanosciences and nanotechnologies provide strong arguments to support the opportunity and importance of the topics approached in this book, the fundamental and applicative aspects related to molecular interactions being of large interest in both research and innovative environments. We expect this book to have a strong impact at various education and research training levels, for young and experienced researchers from both academia and industry.
Publisher: BoD – Books on Demand
ISBN: 9535100793
Category : Medical
Languages : en
Pages : 386
Book Description
In a classical approach materials science is mainly dealing with interatomic interactions within molecules, without paying much interest on weak intermolecular interactions. However, the variety of structures actually is the result of weak ordering because of noncovalent interactions. Indeed, for self-assembly to be possible in soft materials, it is evident that forces between molecules must be much weaker than covalent bonds between the atoms of a molecule. The weak intermolecular interactions responsible for molecular ordering in soft materials include hydrogen bonds, coordination bonds in ligands and complexes, ionic and dipolar interactions, van der Waals forces, and hydrophobic interactions. Recent evolutions in nanosciences and nanotechnologies provide strong arguments to support the opportunity and importance of the topics approached in this book, the fundamental and applicative aspects related to molecular interactions being of large interest in both research and innovative environments. We expect this book to have a strong impact at various education and research training levels, for young and experienced researchers from both academia and industry.
Publications of the Exobiology Program for 1987
Author:
Publisher:
ISBN:
Category : Extraterrestrial anthropology
Languages : en
Pages : 84
Book Description
This report contains a listing of 1987 publications resulting from research supported by the Exobiology Program Office of Space Science and Applications of the National Aeronautics and Space Administration. Research supported by the Exobiology Program is explored in the areas of Cosmic Evolution of Biogenic Compounds, Prebiotic Evolution, Early Evolution of Life, and Evolution of Advanced Life. Pre-mission and pre-project activities supporting these areas are supported in the areas of Solar System Exploration and Search for Extraterrestrial Intelligence.
Publisher:
ISBN:
Category : Extraterrestrial anthropology
Languages : en
Pages : 84
Book Description
This report contains a listing of 1987 publications resulting from research supported by the Exobiology Program Office of Space Science and Applications of the National Aeronautics and Space Administration. Research supported by the Exobiology Program is explored in the areas of Cosmic Evolution of Biogenic Compounds, Prebiotic Evolution, Early Evolution of Life, and Evolution of Advanced Life. Pre-mission and pre-project activities supporting these areas are supported in the areas of Solar System Exploration and Search for Extraterrestrial Intelligence.
Chemical Group Theory
Author: Danail Bonchev
Publisher: Taylor & Francis
ISBN: 9782884490344
Category : Science
Languages : en
Pages : 268
Book Description
First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.
Publisher: Taylor & Francis
ISBN: 9782884490344
Category : Science
Languages : en
Pages : 268
Book Description
First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.